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Second sentence of the abstract: Several typical symptoms of long COVID, such as fatigue, depressive symptoms and cognitive impairment, are also key features of other psychiatric disorders such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and major depressive disorder (MDD)...

Thank you, @dave30th & Ed Young. Good to hear Ed covering the biases introduced by the career selection pressures in medicine.

While the phenomenon is likely quite widespread, I think there is a very good chance that when the underlying mechanisms are finally identified it will turn out to be quite common and explain a lot of health issues currently unexplained or mis-explained. Also a good chance it will be a more...

which appears exaggerated by blood type (more pronounced with blood-type O) Interesting.

Not criticising this particular paper or its authors, but I really wish post-infection was used instead of post-viral.

The "motivated' bit is a red flag too. I have no doubt they are dedicated and motivated. Just not to serving the interests of patients.

What @Trish said. For me PEM is the increase in overall symptom expression/intensity, highly disproportionate to the preceding effort (i.e. non-linear), with a major delayed component (≈ 12-36 hours). I have learned, to some degree, how to avoid provoking it any more than necessary, but at a...

Increased risk of a FND diagnosis after [checks notes] anything and everything.

I agree that no subject should be off-limits to comedy. But how it is done is where the limits kick in.

angiogenic adaptations to hypoxia That alone could explain so much.

Worth noting that beverage alcohol contains a lot more compounds than just ethanol and water (up to several hundred, IIRC), and some of those (e.g. ethyl acetate) contribute disproportionately more to the after effects than the ethanol. So it is possible that we are not reacting to the ethanol...

@Milo Earliest I can find with a quick search are Sharpe 1992, and Wessely 2004.

Another unusual symptom in common with ME. Alcohol reactions and sensitivity are not well characterized in the literature as it relates to post-viral illness. They have been long reported in the ME literature.

Long-standing, and very hard earned. In medical science those standards are written in patients' blood.

This is why the military generally don't like conscription.

Maybe persistent difficult-to-manage pain, especially when additionally burdened with misinterpretation and misattribution and mistreatment by doctors and broader society, causes depressed mood? Long shot, I know. But just maybe.

Psychotherapy and medication adherence are challenging in patients with somatic-type delusional disorder since they do not believe they are delusional and do not see why they would need to be treated for delusional disorder. Spot the flaw in the reasoning.

Always said that the first business of those who get power is to arrange things so they are never held accountable for any adverse outcomes of wielding that power.

According to the research council, MRC and NIHR have since 2020 collectively awarded more than £50 million for research on ME/CFS and long Covid. And how much of those funds went to the psychosomatic ideologues? This. And deconditioning.

Nothing has changed. They are refusing to learn the lessons of history. :grumpy: