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Promising medicines for ME/CFS: call for drug repurposing Deadline: 17 March 2026, 2.00 PM The aim of this call is to fund clinical research into promising medicines for patients with ME/CFS in the Netherlands. This round focuses on drug repurposing or rediscovery. It concerns projects focused...

Discussing the trial here:

Cort Johnson's take on the study https://www.healthrising.org/blog/2025/12/21/muscle-damage-me-cfs-muscle-repair/

Ineffective or effective? Interpreting the effect of CBT on fatigue in ME/CFS. A short analysis of a meta-analysis Mark Vink Friso Vink-Niese This article is a commentary on: Cognitive behavioural therapy for the treatment of chronic fatigue syndrome in adults – a meta-analysis...

Full title: The Locus Coeruleus Norepinephrine Depletion Hypothesis of ME/CFS: A Mechanistic Model with Testable Predictions and Multimodal Study Plans(Protocol Framework) Highlights • ACEs programme the locus coeruleus into a maladaptive high-tonic/low-phasic firing mode • Chronic LC...

Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating multi-system illness with heterogeneity that complicates identifying the pathophysiology, biomarkers, and therapeutic targets. Evidence indicates the importance of immune dysregulation, including the...

From the same author https://www.preprints.org/frontend/manuscript/4bfc2405039882c1ea0ac6f0d4e55e04/download_pub

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem illness with unknown etiology. An estimated 17–24 million people representing approximately 1% of the population are afflicted worldwide. In over half of cases, ME/CFS onset is associated with...

The number of different names we have is already causing confusion in the general poulation as to what our illness is. Changing the name to another without real justification will just lead to further confusion which will be damaging to us. I think we should just stick to what we have now until...

Employment and Support Allowance: outcomes of Work Capability Assessments...

Full title: Large-scale investigation confirms TRPM3 ion channel dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a chronic disease hallmarked by multiple systemic symptoms, including neurocognitive...

Driving discovery: The ME Association invests £1.1m into pioneering research programme! Today, we are incredibly proud to unveil news of our latest investment into ground-breaking research to help world-leading scientists uncover shared pathways between ME/CFS and Long Covid. The ME Association...

Abstract Background: Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a debilitating condition characterized by persistent fatigue and multisystemic symptoms, such as cognitive impairment, musculoskeletal pain, and post-exertional malaise. Recently, parallels have...

https://eu.usatoday.com/story/life/health-wellness/2025/12/02/what-is-chronic-fatigue-syndrome/87403813007/

Abstract Defined by the World Health Organization as a neurological disorder, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disabling illness, affecting millions of people worldwide. First reported in the early nineteenth century, ME/CFS is uniquely characterized by a wide...

The ME Association's take on the debate https://meassociation.org.uk/2025/11/parliamentary-debate-on-me-cfs-i-will-hold-the-ministers-feet-to-the-fire-mp-tessa-munt/

STUDY HYPOTHESIS AND DESCRIPTION ME/CFS, a condition diagnosed by symptoms like extreme tiredness after exertion (known as post-exertional malaise), ongoing fatigue, and mental cloudiness or “brain fog,” may stem from a basic problem with how energy is made and used in the body. We hypothesize...

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic condition without a definitive aetiology, no reliable diagnostic test, and no proven effective treatment. Despite most patients reporting a post-viral onset of illness, findings to date are conflicting...

Benefits and Work newsletter CLAIMANTS TREATED MORE HARSHLY THAN CRIMINALS, REPORT FINDS Sanctions imposed on claimants who miss a single UC interview are larger than the fines handed out to most criminals and have to be repaid nine times faster than criminal courts recommend, a report by the...