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Also I would argue that the MRC are not independent. They have shown themselves incapable of doing a proper assessment and instead repeat QMULs weak statements. Its not like they have investigated and come to a different conclusion they have simply not looked and hence cannot summarise and deal...

I think there is a slightly different question which is whether they got approval to drop recovery as a secondary outcome (along with the step test). I believe the consort guidelines require them to publish all secondary outcomes.

That is one graph from one country so other places could have different profiles or there could be some reporting issues in the data shown here.

I wonder if she actually read the statement and removed it but didn't bother reading the letter to the times and just signed it. The whole thing reads like the normal propaganda put out by the PACE team and the SMC - including the appeal to its ok because others found the same and Cochrane say...

Would it follow from this that adults who get ME as children have something different from adults who get ME as adults? Also when is an adult an adult, I assume the biology doesn't have a strict legal age of adulthood?

Have Fluge and Meller done an analysis of the Rituximab trial by sex - would that back up your theory?

Data won't be available to patients. We should remember that it was patients requesting and analyzing the data that exposed the spin they had put on it not academics or researchers. Also its patients that are most affected. So the MRC are essentially keeping data within a small club and...

Its not clear. The statistical analysis plan dropped the step test and the recovery criteria as secondary outcomes but it is not the protocol. I think in the plan it says something about setting out the way that the primary analysis would be done. If I remember correctly. From the TSG minutes...

Its probably a way of hiding data. I would expect it will keep it out of the hands of patients and pressure seems to be applied to those in the UK who may speak out. But then wasn't the PACE data lost?

Lets not forget that the MRC went to court for QMUL to help suppress the data that showed how much the results were spun A major element of the criticism is around the methodology that was followed in PACE and most of the other CBT and GET trials. Hence this just shows that Fiona Watt has not...

If you edit a message then you should be able to change the file that was uploaded,

I take it as she is not interested in trying. For example, you wrote to her and it seems like she just dismissed your letter without thought and certainly not looking or trying to understand the issues. This says to me that she has an eye on the politics and lobbying rather than understanding...

From the MRC perspective the accusation is that the process was followed but failed to ensure sufficient quality in the result. That should be seen as a serious issue and as a minimum lead to a review of their process.

She hasn't even got this right. The steering committee included independent members but also the PIs so it was not an independent committee.

This isn't about understanding good experimental design this is a civil servant whose job it is to ensure high research standards giving in to lobbying and backing the unbackable. Also standing by her organizations failure to act in the past. In effect this is the MRC saying it is happy with...

I'm assuming that Crawley has had to get someone like Red Whale involved because she is having problems recruiting to Fitnet.

I wonder about the legality of that disclaimer.

Its not just the adverts at the time it started there was a lot of press coverage suggesting recovery rates.

I suspect that may people with severe ME who don't get out of the house may need it (as in they get no sun).

There is a link here http://www.bacch.org.uk/about/documents/SWBACCH07.12.18prog.pdf Perhaps in her personal view she will confess to mistreating children with exercise and failing to get proper informed consent. But I suspect it is more likely that she will be telling others how to threaten...