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  1. ChronicallyOverIt

    Hypothesis Does Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Represent a Poly-Herpesvirus Post-Virus Infectious Disease?, 2025, Ariza et al

    Nvm I read the paper and IM250 would not effect EBV or HHV-6. Also they are saying it’s earlier than the viral replication stage which is what IM-250 stops
  2. ChronicallyOverIt

    Hypothesis Does Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Represent a Poly-Herpesvirus Post-Virus Infectious Disease?, 2025, Ariza et al

    Say this was the issue would IM250 an upcoming herpes virus drug effect this process? It seems like current viral inhibitor herpes drugs have been beat to death with null results
  3. ChronicallyOverIt

    A thread to share your experiences of orthostatic intolerance - problems being upright.

    My Orthostatic intolerance came on quite suddenly when I was already 3 years into CFS. Maybe I had a minor version before but never noticed. I stupidly was very mild at the time and decided to go mountain biking with some old friends, this was a huge huge step up in my activity, but at the...
  4. ChronicallyOverIt

    Trial Report Plasma cell targeting with the anti-CD38 antibody daratumumab in ME/CFS -a clinical pilot study, 2025, Fluge et al

    I also see the IGM vs IGG testing misconception a lot with EBV. Lots of ppl with positive IGG first read this as active and start down that path
  5. ChronicallyOverIt

    Whitney Dafoe Updates

    Thank you for pointing that out. Very confusing since OMF have sponsored this symposium in the past I can find 2017&2018: https://www.end-mecfs.org/community-symposium/ They also advertised this years that contained the borne free lecture...
  6. ChronicallyOverIt

    Whitney Dafoe Updates

    Edit: it has been noted in future posts that this symposium was not sponsored by OMF. I contacted OMF expressing my disappointment and how as a reoccurring donor this is not what I want to see promoted. They have yet to respond it being the weekend. Looking back it seems Joshua has been...
  7. ChronicallyOverIt

    Whitney Dafoe Updates

    Edit: it has been noted in future posts that this symposium was not sponsored by OMF. He can believe what ever he wants! What is upsetting is OMF is giving this a stage.
  8. ChronicallyOverIt

    Whitney Dafoe Updates

    Edit: it has been noted in future posts that this symposium was not sponsored by OMF. I’m upset, a n=1 experiment is driving a supposedly science based charitie. I don’t donate to OMF for personal pet theories to get air time. I’m going to reach out, this seems against the founding of OMF. It...
  9. ChronicallyOverIt

    Whitney Dafoe Updates

    Joshua Leisk spoke at the community symposium for OMF so to say there isn’t influence or separation is wrong. This is directly effecting OMF. I cannot remember but I believe Rengade Research has had lightning talks? Can anyone find that?
  10. ChronicallyOverIt

    The Born Free Protocol

    Interesting looking at Reddit he is the creator of the "Mr.happy Stack" this is wild hadn’t heard about that in a long time, probably one of the most prolific nootropic stacks. Guess this has been a passion for a while, I read about that in 2014ish, I think it goes back to 2011. Interesting all...
  11. ChronicallyOverIt

    The Born Free Protocol

    hair loss alone would be a multi million dollar, really just had to throw that in there too lol Interesting seems like every disease has a grifter selling a potion but instead let’s try to capture the entire market. The thing I don’t get, what is he gaining from this? Most of these guys sell...
  12. ChronicallyOverIt

    The Born Free Protocol

    List of what this protocol “treats” absolutely wild(pulled from the website borne free today): Really got every base covered don’t we! Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)Long COVID, Post-Vaccine SyndromeViral / Post-Viral Chronic Fatigue Post-Exertional Malaise...
  13. ChronicallyOverIt

    Whitney Dafoe Updates

    I’m more surprised anyone that just started eating again was able to tolerate the amount of supplements/probiotics that are given during this. I wonder if he did the full thing, parts? It’s all ambiguous. Yikes my entire feed on X is bornfree. I have worried with some of the research sponsors...
  14. ChronicallyOverIt

    Whitney Dafoe Updates

    The borne free website has crashed do to significant traffic, most likely do to the X post and the Reddit post outlining borne free and Whitney’s improvement. I’d been interested if Ron Davis’s take on the protocol. This is is causing quite a stir in my local groups, with some saying that he...
  15. ChronicallyOverIt

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    If it’s truly not the former, dextro, I would argue that anyone that donated to this study was misled by the last video. Unless this is a different study. Looking forward to Jared clearing this up.
  16. ChronicallyOverIt

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    All those videos just to land on the same drug that’s been tried a million times? The clinical trial says Low Dose naltrexone, not DEXTRO-Naltrexone??
  17. ChronicallyOverIt

    News From Jarred Younger / Neuroinflammation, Pain, and Fatigue Laboratory at UAB, From Aug 2020

    To be fair most people now start extremely small doses then work up to that. All the way to 4.5mg. That being said I had an unpleasant experience with it and didn’t help me one bit even titrating up small doses. I thought Jared wanted to try a different form of the drug? He’s just doing regular...
  18. ChronicallyOverIt

    Running FLAMES on DecodeME data

    Not going to get to work on this for a few days, but I have reached out to some old colleagues in biotech that have experience in this.... hopefully they come through
  19. ChronicallyOverIt

    Running FLAMES on DecodeME data

    Gemini is telling me this BGEN file would be nearly 2TB from UKbio bank… obviously I cannot verify that. Also it would take a insane computer to do an LD on that file size. I must be attacking this from the wrong angle. 1000 genes has premade LD file?
  20. ChronicallyOverIt

    Running FLAMES on DecodeME data

    Holy cow, step 4 fine mapping is no joke. I wouldn't even say this is programming, more like puzzle solving and plugging in the right inputs. Files needed for a FINEMAP: Master file Z file LD (Linkage disequilibrium) file. This must be created from the software LDstore LDstore requires...
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