Full title: Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome
Background
Post Exertional Symptom Exacerbation (PESE) is a characteristic symptom of Post-COVID Syndrome (PCS)...
I have limited context, and I'm also aware of how challenging it can be to create a good questionnaire, however my thought on all of these questions, and probably some of the others as well,
is that it's not clear whether the person answering should factor in the potential travel to the...
Well, I'm not the expert on these things but I would assume that is one of the reasons why we are using the data from the UK Biobank as our control group, thereby controlling for geography as much as is possible.
Highlights
• Disability level (assessed by six-minute walk test) in people with multiple sclerosis was estimated using the data collected from wearable devices in free-living conditions.
• Fitbit minute-level step counts were analysed from which features were extracted.
• Elastic net, gradient...
Background
As a group, individuals with functional neurological disorder (FND) report an approximately 3-fold increase in adverse life experiences (ALEs) compared to healthy controls. In patients with FND, studies have identified a positive correlation between symptom severity and the magnitude...
Full title: Psychological consequences of long COVID: comparing trajectories of depressive and anxiety symptoms before and after contracting SARS-CoV-2 between matched long- and short-COVID groups
Abstract
Background
There is a growing global awareness of the psychological consequences of long...
"Case definition
CYP with severe ME/CFS were defined using a three-stage procedure. First, paediatricians used a surveillance case definition to identify CYP (box 1). The study team then applied the exclusion criteria. Cases were then reviewed by the expert ME/CFS panel, which consisted of...
ME Research UK.
"Absolutley amazing! Unbelievable!
We realised it was a 'big ask' for the 'Big Give' but you have, our wonderful supporters, topped our fundraising target of £7000 which will be match funded by our Pledgers. Not only that but the total amount raised (including matched funds) is...
Abstract
Background
Intestinal inflammation disrupts the microbiota composition leading to an expansion of Enterobacteriaceae family members (dysbiosis). Associated with this shift in microbiota composition is a profound change in the metabolic landscape of the intestine. It is unclear how...
Abstract
Metabolites of glycolytic metabolism have been identified as signaling molecules and regulators of gene expression, in addition to their basic function as major energy and biosynthetic source. Immune cells reprogram metabolic pathways to cater to energy and biosynthesis demands upon...
Abstract
Understanding the impact of COVID-19 on muscle strength may help to elucidate the organ systems that contribute to acute and chronic COVID-19 sequelae. We questioned whether patients with postdischarge symptoms after COVID-19 had compromised muscle strength compared with a control...
Full title: STIMULATE-ICP-Delphi (Symptoms, Trajectory, Inequalities and Management: Understanding Long-COVID to Address and Transform Existing Integrated Care Pathways Delphi): Study protocol
Abstract
Introduction
As mortality rates from COVID-19 disease fall, the high prevalence of long-term...
Summary
Background
Many of the 10–20% percent of COVID-19 survivors who develop Post COVID-19 Condition (PCC, or Long COVID) describe experiences suggestive of stigmatization, a known social determinant of health. Our objective was to develop an instrument, the Post COVID-19 Condition Stigma...
Abstract
Background
To update and internally validate a model to predict children and young people (CYP) most likely to experience long COVID (i.e. at least one impairing symptom) 3 months after SARS-CoV-2 PCR testing and to determine whether the impact of predictors differed by SARS-CoV-2...
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