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Abstract Background Long Covid is recognised as a complex condition characterised by multiple, interacting and fluctuating symptoms which impact everyday life in diverse ways. The extent of symptom clusters and variability supports interventions that can accommodate heterogeneity, such as...

Abstract With increasing numbers infected by SARS-CoV-2, understanding long-COVID is essential to inform health and social care support. A Scottish population cohort of 33,281 laboratory-confirmed SARS-CoV-2 infections and 62,957 never-infected individuals were followed-up via 6, 12 and...

So I'm not sure how my refusal as a child to engage in the demands of late capitalism then matches with the relatively successful career I had in sales which I then had to give up as my ME got worse. I guess their view would be that in unconsciously denying my unconscious refusal led me to...

The Institute for Neuro-Immune Medicine at Nova Southeastern University, "a premier research and treatment center for ME/CFS, GWI and other related neuroimmune disorders", where Nancy Klimas is based is now offering cupping - "Cupping may look strange, but this pain-free treatment has been...

"Steve Gardner from Precision Life on the power of the =AZW4sE5GzzD-AF-sP0MbKc-i4DCvk8WS1wOn2E920_auNZ2gPj4VjSdf7XbXHOQ5YAgp7QeVttI9jBR0ZTc1odCT5JKRyxQYajgKkH84nw5UOl1eio7FyZ_ozP5WkAP7CEup--6Umm-QebOjuVlmuC_6jwp1YZTvg_fhNWOV4xOWU5w9LiQG5t1pCil1-3lmVPA&__tn__=*NK-R']#DecodeME questionnaire "The...

ABSTRACT Mental Health Practitioners (MHPs) have a unique opportunity to provide resources and support to those suffering from Long COVID (LC), the post infectious illness that often follows an acute SARS-CoV-2 infection. In working with these individuals, MHPs can learn from the experiences of...

Abstract Understanding the mechanisms of coronavirus disease 2019 (COVID-19) disease severity to efficiently design therapies for emerging virus variants remains an urgent challenge of the ongoing pandemic. Infection and immune reactions are mediated by direct contacts between viral molecules...

Key Points Question Among individuals who had symptomatic SARS-CoV-2 infection in 2020 and 2021, what proportion experienced common self-reported Long COVID symptom clusters 3 months after initial infection? Findings This observational analysis involved bayesian meta-regression and pooling...

A supporter of the study has independently produced this short film promoting the study.

Please share if you can. "Wow, 18,000 registered participants. 13,500 completed the questionnaire = a huge dataset on ME. Not everyone will be invited to provide a DNA sample so we need your help to #DecodeME. Help us now to recruit to the world’s largest study for people with #MECFS"...

No, it's not. It is encouraging desperate sick people to take something that they think is a treatment, and to report back in order to influence other people as to what the 'right' dose is. It's unethical and dangerous. We've seen it before with various 'cures', and no doubt will see it again...

We don't ask.

Abstract Objective The aim of this study was to compare the measure of grip strength against other validated methods of measuring frailty. Materials and methods This was a single-center, cross-sectional study that took place at the Westchester Medical Center Pre-Procedural Testing Clinic. The...

Introduction: Mutations and misfolding of membrane proteins are associated with various disorders, hence they make suitable targets in proteomic studies. However, extraction of membrane proteins is challenging due to their low abundance, stability, and susceptibility to protease degradation...

Abstract Most COVID-19 patients recovered with low mortality; however, some patients experienced long-term symptoms described as “long-COVID” or “Post-COVID syndrome” (PCS). Patients may have persisting symptoms for weeks after acute SARS-CoV-2 infection, including dyspnea, fatigue, myalgia...

Sadly, yes. But if we, at least, don't point that out there is little counterpoint to the almost inevitable hype.

"ME/CFS patients with high HHV-6 load have a more severe course of the disease, thus confirming that the severity of the disease depends on the viral load—the course of the disease is more severe with a higher viral load." Or the immune system of someone who is less well will find it harder to...

News in Brief for w/c 3rd Oct https://www.facebook.com/sci4me/posts/pfbid02LFhfR18tQeS8qhkYBkvJjjuvu855xYMFy3AwDqz3QjfTf2kVeUAYrNLvdD7djRRCl Research papers thread https://www.facebook.com/sci4me/posts/pfbid02kYwygzbaFHw7CKALTsbEkXsGWYoKZsTx9jed4sWNNA5aXjSNfp55k7qtcECSwJJKl

Social media moves more quickly than established systems for formal trials? Of course it does, that should be no surprise to anybody. And what should not surprise anybody is that a quick Twitter poll, which will be open to all kinds of bias, on the efficacy of an alleged treatment should not be...

Then you will be delighted to know that DecodeME (sign up to the study at www.decodeme.org.uk) includes a question about course of illness in which an option is available to indicate progressive deterioration.