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  1. J

    Teclistamab for ME/CFS

    Thank you for this report. Sorry it wasn’t successful for you. Just to clarify, you received low dose Tecli? What were your dosages/number of injections. Any CRS? Also Habets is claiming success with this treatment—have you heard of any other of his patients who improved with Tecli? Thanks.
  2. J

    News from the USA, United States of America

    https://www.statnews.com/2025/12/27/nih-neurological-disorders-stroke-institute-director-koroshetz-ousted/ Director of NIH neurological disorders institute is ousted, adding to leadership churn Agency declines to reappoint Walter Koroshetz, who has led NINDS since 2015
  3. J

    STIMULATE-ICP: [...] Phase III, open label, adaptive platform randomised drug trial in [LC]: [Protocol], 2023, Forshaw et al

    Unbelievable. What “leading researchers” did they ask to get this p.o.s. included?
  4. J

    Proxy Praxis: How Surrogate Endpoints Can Speed Drug Development

    Haven’t read yet. https://ifp.org/proxy-praxis-how-surrogate-endpoints-can-speed-drug-development/ “ In drug development, speed is critical. Each additional year a clinical trial takes can cost hundreds of millions of dollars, due both to ongoing trial expenses and the loss of valuable market...
  5. J

    A Study to Assess Anktiva in Patients With Long Covid-19. (INTERRUPT_LC)

    Dr. Steven Alberts, MD Can you please remind us again that you are a physician?
  6. J

    Hypotheses and Research Directions for ME/CFS

    I’ll just say that if ME/CFS is an immune-mediated diseases like a variant of an autoimmune disease, then it should be relatively easy to treat since there are now so many new treatments, especially mab drugs—e.g. Daratumumab. If it is a brain disease like schizophrenia/depression or a...
  7. J

    Hypotheses and Research Directions for ME/CFS

    To make responses more manageable, would be better to ask one question per thread…….
  8. J

    Why can't good ME/CFS researchers get more funding?

    The fringe research outfits will close shop once real pharma gets involved. Does multiple myeloma/multiple sclerosis have these fringe research groups involved—no I don’t think so. JNJ loves multiple myeloma research cause it makes billions from it (Tecli and Dara). And they can spend millions...
  9. J

    A Study to Assess Anktiva in Patients With Long Covid-19. (INTERRUPT_LC)

    That Gustavo guy is zero evidence. I thought maybe he disappeared, but I guess not.
  10. J

    Why can't good ME/CFS researchers get more funding?

    This is sort of a good question, and partially the answer depends on the phrase “good quality”. I mean the research funded by a organization will reflect the biases/culture/interest of the core group. For example, AP believes LC ME/CFS is caused by viruses or other microorganisms. So she looks...
  11. J

    Why can't good ME/CFS researchers get more funding?

    This conversation has been split from Whitney Dafoe Updates How did “Polybio” become a multi million dollar research foundation “based on viral persistence”? How did David P become an overnight world expert on ME/CFS despite no background in immunology? How did AP become the scientific...
  12. J

    Works of fiction where characters have ME/CFS

    I watched this last night and thought about this also. Her character wasn’t particularly well developed. If she is a great cellist and presumably pretty well educated, why would she believe a local priest could cure her? But the plot of this movie was way too convoluted for my brain. First...
  13. J

    In vitro B cell experiments explore the role of CD24, CD38 and energy metabolism in ME/CFS, 2023, Armstrong et al

    Yes Anktiva. @ryanc97 is the expert here. https://immunitybio.com/immunitybios-anktiva-reverses-lymphopenia-and-extends-overall-survival-in-patients-with-advanced-non-small-cell-lung-cancer-resistant-to-checkpoint-therapy/ Also Blueberries.
  14. J

    The Born Free Protocol

    This Doc apparently treats patients with BF
  15. J

    The Born Free Protocol

    The host of the program is vehemently opposed to equating ME/CFS with LC.
  16. J

    The Born Free Protocol

    White lab coat comes up….
  17. J

    The Born Free Protocol

    Joshua giving a seminar on BF now.
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