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  1. Alvin

    Circulating leptin levels in patients with [ME], [CFS] or fibromyalgia a systematic review protocol, 2020, Musker et al

    I agree, at this point we are ahead of many of the researchers so they would actually benefit from consulting us until they get up to speed (assuming they actually want to get up to speed)
  2. Alvin

    Circulating leptin levels in patients with [ME], [CFS] or fibromyalgia a systematic review protocol, 2020, Musker et al

    I'm not that cynical, progress does happen and we do need to cast a wide net because if we only researched what we know will give the results we want we would not have to research in the first place. However adding intelligence to research will increase the odds of success.
  3. Alvin

    Circulating leptin levels in patients with [ME], [CFS] or fibromyalgia a systematic review protocol, 2020, Musker et al

    Reminds me of this, though i assume they don't believe they are doing this https://en.wikipedia.org/wiki/Streetlight_effect
  4. Alvin

    Circulating leptin levels in patients with [ME], [CFS] or fibromyalgia a systematic review protocol, 2020, Musker et al

    Basically this, they may find something but adding a change in blood chemistry by pushing the thing that burns us is more likely to show something useful. If anyone knows a way to give them this 'revolutionary' idea please go for it To be honest i don't think what they are doing is going to find...
  5. Alvin

    Anyone get root canal (either before or after ME onset)?

    The K2 will eliminate the pain (except when biting which is physical agitation like jabbing your arm with a fork), but won't easily fix them unless you can take it daily at a high enough dose and with Vitamin A & D. But wisdom teeth not erupted won't work well with K2. I suggest getting a...
  6. Alvin

    Hypothesis piece by Amy Proal, a microbiologist with ME/CFS

    I've been working on analyzing the pyruvate dehydrogenase Fluge and Mella paper, (without a medical degree and with severe neurological impairments) and i would agree, if something is causing signaling to go wrong or is somehow doing the signaling itself it would explain a lot. I do wonder if Dr...
  7. Alvin

    Documents from the SMILE trial

    Can't read the link (works but no brain power) but thats silly but not unexpected, They probably think we are being open and giving you everything, that we deem you worthy of seeing and we will argue meets relevant laws.
  8. Alvin

    Open Letter Seeking Health Equity for ME in Canada! Please sign and share

    I'm not speaking of exceptional access (typically on a case by case basis), i speak of regular approval as we have for any other prescription drug. I have some personal experience i'm not going to get into on a public forum somewhat related to this. For drugs to get approved there is a dance...
  9. Alvin

    Open Letter Seeking Health Equity for ME in Canada! Please sign and share

    Its efficacy is unproven and inconsistent and the manufacturer makes promises then ignores them. Health Canada won't approve the drug because patients ask them to without data and its a dead end at this point. That said money towards research on the disease mechanism would be easier to get...
  10. Alvin

    Tymes Trust - No reported harassment of staff at Bristol University

    This is random but that is amazing penmanship, i could not be that good on large print
  11. Alvin

    Is Cognitive Behavioral Therapy the Gold Standard for Psychotherapy?

    Edited: I don't believe in antidepressants as a cure and alcohol and marijuana are not cures either :facepalm: Very true, its hard to analyze something subjective and there is a lot of money involved. Also our "official" understanding of psychology is practically still in its infancy (with a...
  12. Alvin

    Is Cognitive Behavioral Therapy the Gold Standard for Psychotherapy?

    When they work they are making you slightly high. Peter Breggin calls it medication spellbinding, when a drug makes your problems go away its not fixing anything, its covering it up, slightly better then alcohol or marijuana because your not inebriated. For a second i thought you said...
  13. Alvin

    Microbiome testing reports discussion

    I always suspected this but have wondered why
  14. Alvin

    13th Invest in ME Research International ME Conference - 1st June 2018

    I wonder if OMF will do another symposium next year.
  15. Alvin

    Anyone get root canal (either before or after ME onset)?

    A root canal kills the tooth and eventually the tooth will completely shatter. It typically just delays removal, often by years, sometimes longer. I would get it filled and start taking Vitamin K2 (MK4). Only caveat, do you still have your wisdom teeth and are they unerupted. If the answer to...
  16. Alvin

    Are there symptoms you had in the early stages of ME that you no longer get?

    I used to be able to do more then crash hard and the PEM was more delayed up to a week (once or twice), now its far less before conking out and PEM within 24 hours (typically) :cry:
  17. Alvin

    Is Cognitive Behavioral Therapy the Gold Standard for Psychotherapy?

    I disagree, as my arthritis and painkiller example shows. If i had no idea what a painkiller does i can argue passionately that it treats the core of arthritis, some even reduce inflammation, further "proving" my wrong hypothesis. Same with antidepressants and depression, they work because they...
  18. Alvin

    Is Cognitive Behavioral Therapy the Gold Standard for Psychotherapy?

    Keep in mind you can get positive results but come to the wrong conclusion. If i take a painkiller my arthritis will hurt less but i have not treated the cause, only masked it. One could make the argument its curing it between doses (one who does not understand what a painkiller really does)...
  19. Alvin

    Is Cognitive Behavioral Therapy the Gold Standard for Psychotherapy?

    CBT is basically what an android would come up to treat emotions that it can't comprehend. Real therapy works when the clinician understands what they are doing (very rare, education today is about CBT) and when there is a good fit between counselor and client.
  20. Alvin

    Tymes Trust - No reported harassment of staff at Bristol University

    Well written. I hope it has a wide readership
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