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No brain power to read the study but raising dopamine is only a Dexedrine or Levodopa tablet away

Very well done :) The long version is very long, i already fried my brain on the short one so in future i'll take a stab at the long version :) Oh and something to point out, ethical scientists typically argue things based on the merits because we are right, but the other side will play dirty...

That is insanely good news :) I hope they don't price it out of reach or destroy the life savings of sufferers.

I wonder if this drug would be superior to something like Selegiline or Rasagiline.

Agreed :cry: Since it would be unethical to perform this type of experiment in humans we use animal surrogates, with the knowledge that the data may not hold species to species but in the hope there are parallels as there often are. All that said i do not condone doing torturous treatments on...

I find these likely coincidental spontaneous improvements attributed to unproven and likely sham treatment stories very annoying :emoji_face_palm:

It basically seems to come down to science is failing our ideology so disregard it :emoji_face_palm: Funny that it never comes down to science is not backing us up, why is that, lets find out why and improve our processes. :emoji_face_palm:

I don't have the energy to pick apart the multiple pieces of nonsense in that article so i'll just say its a perfect example of why the facepalm emoji is so necessary :emoji_face_palm:

Here is an example of using statistics to "prove" something, by playing with numbers one can prove opposites are correct https://projects.fivethirtyeight.com/p-hacking/

Technically i agree, and i do know a thing or two about statistics (i did in a previous life anyways), and suffice it to say 87 patients won't give you a 95% confidence interval :laugh: What i was getting at is this seems to be a ploy to make a quick buck by stacking numbers to make it so and a...

Bigger numbers are always nice but if there is no statistical significance for 87 patients i don't think 870 patients will fare much better, assuming they all have the same disease. Bigger numbers won't make something that doesn't work, work Fancy multi vitamin with a few things added. How much...

I've found its worth figuring out the mechanism, if something works can we determine why it works, because that can help us cut through any statistical questions and can hopefully lead to further treatment optimizations and hopefully even better future treatments. Hard to do for psychosomatic...

Indeed I have heard of a few instances where blood tests or genetic tests can determine if a medication will be tolerated or what doses to start with but this type of medicine is more star trek-ish then realistic so far. By the time the Enterprise is built i expect ME/CFS will have been cured :)...

I did say almost nonsense, Its near term potential is not very high except for a few niche areas. In a few generations it will be huge and the longest journey does start with a single step, so i support such research but would not direct huge amounts of resources away from other research to this...

This is almost nonsense, we do not have the technology to get to medicine at this level. That said we will one day and its not a terrible idea, but if we dump money on it now in a few generations we would get to this level. At this point there is far greater return in spending limited money...

@Liv aka Mrs Sowester comes to mind

They may be the host of the German embassy which is technically German soil? :D

We really need a disease mechanism, it will help immensely in almost every area from smashing the GET/CBT house of cards to a diagnostic test for ME/CFS to research directions to vectors to test treatments against. The fact they are focusing on T cells and genetics suggests this is what they...

If people with ME/CFS are welcome i would go, not sure how i would afford it but i would figure that out later :D