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  1. Sean

    David Tuller: Trial By Error: Professor Sharpe’s Pre-Hearing Briefing for Monaghan

    So the red dots that vanish are the missing outcome data? Rather a lot of them. [EDIT: Yes, they are. Just seen the new thread of PACE graphs and gifs.]
  2. Sean

    David Tuller: Trial By Error: Professor Sharpe’s Pre-Hearing Briefing for Monaghan

    The subjective-objective correlation test I most want to see is the 6MWT for the GET arm. It is the only objective outcome that delivered a statistically significant result (though not clinical significance).
  3. Sean

    David Tuller: Trial By Error: Professor Sharpe’s Pre-Hearing Briefing for Monaghan

    Be an interesting exercise to keep a list of the excuses/responses they go through, to see how it changes over time as each one fails to stem the tide, and they have to move onto the next decreasingly plausible one down the list.
  4. Sean

    Michael Sharpe skewered by @JohntheJack on Twitter

    He must love being harassed and intimidated. :whistle: ;)
  5. Sean

    David Tuller: Trial By Error: Professor Sharpe’s Pre-Hearing Briefing for Monaghan

    Clinical trials are to compare treatments with each other, placebo, or no treatment at all, not to compare treatments with themselves over time. Sharpe himself says so earlier in the same document: It is a fact that the CBT & GET arms maintained their effect size at follow-up. But that is not...
  6. Sean

    MAGENTA (Managed Activity Graded Exercise iN Teenagers and pre-Adolescents) - Esther Crawley

    Patients, as usual. Oh, wait, you meant who is funding the study. ;)
  7. Sean

    Objective assessment of diverse types of MS related fatigue and fatiguability

    A question both tongue-in-cheek, and serious: How does the researcher tell the difference between the 'active' water and the 'inactive' control water? All water has been in contact with some other substance at some point, and subsequently diluted to the nth degree (thus rendering it mightily...
  8. Sean

    "The three myths of the NHS"

    My GP clinic bulk bills. I am in a semi-rural area.
  9. Sean

    United Kingdom: National Health Service (NHS) news

    Protected species, mate.
  10. Sean

    Member comments wanted: First section (Why the guideline is needed) of the NICE ME/CFS guidelines draft scope

    Not too bad. Main issue is the usual obsession with fatigue.
  11. Sean

    MAGENTA (Managed Activity Graded Exercise iN Teenagers and pre-Adolescents) - Esther Crawley

    Very disturbing stuff. All we can do is keep pointing it out, and document everything so eventually this despicable behaviour can be held to account.
  12. Sean

    Reports from participants in GET and CBT trials

    So what, in their bizzaro version of science, does count as evidence for a failed therapy? Where is the possibility for falsification? Sometimes I think they are just taking the piss.
  13. Sean

    David Tuller: Trial by Error: My exchange with Professor Bishop

    Quite apart from the sheer idiocy and danger of it, there is something profoundly disrespectful about it, isn't there.
  14. Sean

    Medscape: Chronic Fatigue Syndrome Takes Down Doctors, Too

    Sure they can. It is handwriting they have trouble with.
  15. Sean

    Application of head scraping combined with five-tone therapy in CFS of liver qi stagnation, Meiling et al, 2018

    In equal temperament the ratio between adjacent notes of the chromatic scale (i.e. a semitone apart) is the twelfth root of 2. Multiply the fundamental frequency of any note by that factor gives you the next note up the chromatic scale. [EDIT: Just noticed Bruce's post. He gave the compact...
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