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  1. Andy

    Two symptoms can accurately identify post-exertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome 2023 Davenport et al

    BACKGROUND: Post-exertional malaise (PEM) is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) yet its diverse manifestations make it difficult to recognize. Brief instruments for detecting PEM are critical for clinical and scientific progress. OBJECTIVE: To...
  2. Andy

    Developing a blood cell-based diagnostic test for ME/CFS using peripheral blood mononuclear cells, 2023, Xu, Morten et al

    Preprint. Paper now published, see this post Abstract A blood-based diagnostic test for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis (MS) would be of great value in both conditions, facilitating more accurate and earlier diagnosis, helping with current...
  3. Andy

    Noise cancelling devices for sleep?

    An alternate suggestion that we have been using to help with noise from other flats is a white noise generator. Lots of options out there, and perhaps might not be suitable for your situation, but we have found that it definitely helps to make noise from elsewhere less disturbing to us.
  4. Andy

    USA: National Institutes of Health (NIH) intramural ME/CFS study

    More from the post that John Mac linked to
  5. Andy

    International: Science for ME social media posts

    Published papers thread for w/c 13th March. Facebook: https://www.facebook.com/sci4me/posts/pfbid02mSFyuTg5gVhdykEj1nTTGRjodWmfyyeU7HYUYtsmcT9XQ7c3YVyvk1NsAVdXwSo7l Mastodon: https://med-mastodon.com/@s4me/110055051421628426
  6. Andy

    International: Science for ME social media posts

    News in Brief posts for w/c 13th March. Facebook: https://www.facebook.com/sci4me/posts/pfbid0CuewzMtTgxAkPSqpBLtetkbYeQ3fpHVp2cU3i4sofrnmpXv4EhEWvfGXBxVu6zDMl Mastodon: https://med-mastodon.com/@s4me/110050102951042269
  7. Andy

    Clinician-rated outcomes of patients with functional neurological disorders treated in an outpatient clinic 2023 LaFrance Jr. et al

    Highlights Limited treatment options exist for patients with functional neurological disorders. Psychotherapeutic treatments show encouraging results for FND in research settings. A limited number of published studies explore motor and seizure FND outcomes in the natural outpatient clinic...
  8. Andy

    Patient and public involvement within epidemiological studies of long COVID in the UK, 2023, Routen et al

    Several major epidemiological studies have been funded in the UK with the goal of better understanding the epidemiology of persistent symptoms following SARS-CoV-2 infection. Investigators from nine of these studies formed the National Long COVID Research Working Group in 2021 to share key...
  9. Andy

    Characterization of exhaustion disorder and identification of outcomes that matter to patients, 2023, Lindsäter et al

    "4.2 Characterization of exhaustion disorder Demographic and clinical data collected from ED-participants through closed-ended questions and symptom questionnaires in the present study indicate a clinical picture that is similar to findings from previous qualitative and quantitative inquiries...
  10. Andy

    Characterization of exhaustion disorder and identification of outcomes that matter to patients, 2023, Lindsäter et al

    "Given the substantial societal impact of chronic stress and fatigue, there is a need for further investigation into symptom presentation, diagnostic characterization, and steps towards standards regarding outcome domains to measure in clinical trials. Indeed, a recent review of all published...
  11. Andy

    Characterization of exhaustion disorder and identification of outcomes that matter to patients, 2023, Lindsäter et al

    "In response to increasing sick leave rates due to mental disorders in the late 1990's in Sweden, together with clinical observations that many sick-listed individuals reported prolonged exposure to psychosocial stressors and symptoms of fatigue, tentative criteria for a new diagnosis...
  12. Andy

    Characterization of exhaustion disorder and identification of outcomes that matter to patients, 2023, Lindsäter et al

    Diagnostic Criteria for exhaustion disorder (ED) (F43.8 A) A. Physical and mental symptoms of exhaustion during at least 2 weeks. The symptoms have developed in response to one or more identifiable stressors, which have been present for at least 6 months. B. Markedly reduced mental energy...
  13. Andy

    Endothelial dysfunction in ME/CFS patients, 2023, Sandvik, Mella, Fluge et al

    Apologies if I'm duplicating anything but I wonder if what they did in this study might have some relation to Dr Alan Moreau's new, low-stress protocol for provoking PEM.[Thoughts?], which also involves an arm pressure cuff. The thought was inspired by spotting this, Preprint: Altered Tissue...
  14. Andy

    Altered Tissue Oxygenation in Patients with Post COVID-19 Syndrome 2023 Schäfer et al

    For published version see Altered tissue oxygenation in patients with post COVID-19 syndrome (2023, Microvascular Research) ******************** Pre-Print https://www.researchgate.net/publication/369239099_Altered_Tissue_Oxygenation_in_Patients_with_Post_COVID-19_Syndrome Background: Post...
  15. Andy

    Stress, mental ill-health and functional somatic syndromes in incident and chronic sleep disturbance in a general adult population 2023 Enkvist et al

    Objective Sleep disturbance may constitute health problems for the afflicted individual, but documentation of its chronicity is sparse. The objective was to investigate the extent to which incident and chronic sleep disturbance are associated with stress, mental ill-health and functional somatic...
  16. Andy

    Understanding pediatric long COVID using a tree-based scan statistic approach: an EHR-based cohort study from the RECOVER Program 2023 Lorman et al

    Abstract Objectives Post-acute sequalae of SARS-CoV-2 infection (PASC) is not well defined in pediatrics given its heterogeneity of presentation and severity in this population. The aim of this study is to use novel methods that rely on data mining approaches rather than clinical experience to...
  17. Andy

    IVIg-induced headache: prospective study of a large cohort with neurological disorders 2023 Bayır et al

    Background Intravenous immune globulin (IVIg) is frequently used in some neurological diseases and is also the first-line therapy in Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy. We aimed to evaluate the frequency and characteristics...
  18. Andy

    Somatic symptoms in burnout in a general adult population 2023 Hammarström et al

    "Among the 3406 participants, 175 were excluded due to having responded to less than half of the items on the SMBQ, PHQ-15 and/or HADS, resulting in a study sample of 3231 participants. Of these, 687 met the criterion for burnout (global SMBQ score ≥ 3.75), and the remaining 2544 participants...
  19. Andy

    Somatic symptoms in burnout in a general adult population 2023 Hammarström et al

    Highlights • Fatigue, pain and gastrointestinal symptoms are particularly common in burnout. • These symptoms show 2- to 9-fold increased risk when adjusted for negative affect • The risk of burnout increases 1.52 times with each additional symptom Abstract Objective Burnout results in...
  20. Andy

    Functional Neurological Disorder (FND) - articles, social media and discussion

    In case anybody has the stomach to watch it. "In this Dystonia Facts video Prof Mark Edwards, St George’s University Hospital, London UK covers Functional Dystonia also known as Psychogenic Dystonia.The importance of properly diagnosing the condition and treatment plans that follow."
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