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Abstract Ebola virus (EBOV) causes severe hemorrhagic fever in humans with high mortality. In Ebola virus disease (EVD) survivors, EBOV persistence in the eyes may break through the inner blood–retinal barrier (iBRB), leading to ocular complications and EVD recurrence. However, the mechanism by...

Looking at the supplemental material file available, they included ME in their search terms. Being paywalled I can't tell if it is actually mentioned in the paper.

Abstract Persistent physical symptoms (PPS) remain a challenge in the healthcare system, mainly due to time-constrained consultations, uncertainty and limited specialised care capacity. Self-help interventions may be a cost-effective way to widen the access to treatment. To make a foundation...

Abstract SARS-CoV-2 infection is clinically heterogeneous, ranging from asymptomatic to deadly. A few patients with COVID-19 appear to recover from acute viral infection but nevertheless progress in their disease and eventually die, despite persistent negativity at molecular tests for...

Kara Jane died of M.E. When will we take post-viral illness seriously? "Two days into 2023, the friends of bedbound musician Kara Jane, 32, shared the heartbreaking news that she had sadly passed away. “In the end, her body was too frail to survive,” they wrote on her website that evening...

From Patient-Led Research Collaborative Twitter thread "Attention all those who value patient-led research! In partnership with @CMSSmed & funded by @PCORI, we have developed scorecards that evaluate how effective a patient group and research partner collaboration will be at conducting truly...

Project Summary Background: While patients are increasingly engaged in clinical research and clinical registries in an advisory capacity, collaboration and patient leadership in clinical effectiveness research remains limited. Newer patient-led participatory outcomes research for Long COVID-19...

Patient and carer involvement at every decision making stage at least, and preferably within work teams on every project. Substantive monetary compensation for those representatives, and adaptation of the research workflow to the limitations of those representatives. Yes, this will mean research...

Abstract Humoral immunity after infection or after vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been attributed a key part in mitigating the further transmission of the virus. In this study, we used a commercial anti-Spike immunoglobulin G (S-IgG) assay...

Objective Neutralizing antibodies are among the factors used to measure an individual's immune status for the control of infectious diseases. We aimed to confirm the persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibody levels in patients who had...

Social media post. "Today our team members Chris Ponting, Claire Tripp and Diana Garcia visited the National Biosample Centre to meet the team processing DNA spit kits for DecodeME. We're grateful to the team there for showing such genuine interest in the lives of people with ME. Our team...

So they are claiming that diet isn't the reason for the differences found. "No enrolled subject had taken antibiotics, probiotics, prebiotics or antifungal medications for 3 months before faecal sample collection. " "Moreover, both groups had the same dietary structure. The staple food mainly...

Abstract Background Advancements in research have confirmed that gut microbiota can influence health through the microbiota–gut–brain axis. Meditation, as an inner mental exercise, can positively impact the regulation of an individual’s physical and mental health. However, few studies have...

"Disability occurs in many different forms. An invisible disability, or non-visible disability, is an impairment or health condition that is not immediately obvious. This POSTnote provides an overview of invisible disability in the UK. It outlines types of invisible disabilities and relevant...

Full title: Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway Abstract Background As the major pathophysiological feature of obstructive sleep...

A member of the community has let us know that they have had success in asking if a local, to them, newsletter would feature the poster advertising the study. Circulation of only 2,000 households but we obviously never know who might see it and all efforts like these add up.

Abstract Active episodes of inflammatory bowel disease (IBD), which include ulcerative colitis and Crohn’s disease, coincide with profound shifts in the composition of the microbiota and host metabolic energy demand. Intestinal epithelial cells (IEC) that line the small intestine and colon...

ABSTRACT Background Emerging Long COVID research indicates the condition has major population health consequence. Other chronic conditions have previously been associated with functional and mental health challenges – including depression, anxiety, post-traumatic stress disorder (PTSD), suicide...

ABSTRACT Background: Long COVID induces a substantial global burden of disease. Objective: We examined the prevalence of long COVID, its symptom patterns, and its risk factors. Methods: We performed a population-based, multi-centre survey by a representative sampling strategy via the...

Abstract Introduction Despite a growing body of research on the risks of SARS-CoV-2 infection during pregnancy, there is continued controversy given heterogeneity in the quality and design of published studies. Methods We screened ongoing studies in our sequential, prospective meta-analysis...