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The News in Brief posts from February on Reddit.

Full title: The short-chain fatty acid butyrate exerts a specific effect on VE-cadherin phosphorylation and alters the integrity of aortic endothelial cells Short-chain fatty acids (SCFAs) like butyrate (BUT) largely influence vascular integrity and are closely associated with the onset and...

Now published. Abstract Background Few prospective studies of Long COVID risk factors have been conducted. The purpose of this study was to determine whether sociodemographic factors, lifestyle, or medical history preceding COVID-19 or characteristics of acute severe acute respiratory syndrome...

Asthenia is a clinical syndrome that can be manifest in almost all somatic, infectious, and neurological diseases. Initially a protective mechanism indicating depletion of energy resources, asthenia can become a pathological and extremely disabling condition, and can even progress to an...

Brain fog is a kind of mental problem, similar to chronic fatigue syndrome, and appears about 3 months after the infection with COVID-19 and lasts up to 9 months. The maximum magnitude of the third wave of COVID-19 in Poland was in April 2021. The research referred here aimed at carrying out the...

Confusingly though "Diagnosis of ME/CFS was based on the Canadian Consensus Criteria (2003).17,18 Using the DePaul symptom questionnaire,19 patients who meet five or more of the six criteria are considered to have ME/CFS" Even more confusingly they say "The DePaul symptom questionnaire, [used]...

"Post exertional malaise During the development phase, the trial team were contacted by several organisations representing the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) community with concerns relating to the potential harms of unsupervised vigorous exercise for people with...

Could explain why I experience bowel movements slowing or stopping outright while in PEM.

Abstract Background: Clinical investigations of long-term effects of coronavirus disease 2019 (COVID-19) are rarely translated to objective findings. Objectives: To assess the functional capacity of individuals reported on deconditioning that hampered their return to their pre-COVID routine...

Full title: Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/coronavirus disease 2019 (COVID-19) pandemic...

Published papers thread for w/c 20th Feb. Facebook: https://www.facebook.com/sci4me/posts/pfbid03RzM1tpPB8RRow1oyMk9La3TzNrCfJJA7HXp6b1drwKEQgumDyw5ixbdH46YDhpfl Mastodon: https://med-mastodon.com/@s4me/109935875767105617

News in Brief posts for w/c 20th Feb. Facebook: https://www.facebook.com/sci4me/posts/pfbid02rvV5mtZfQMa6wyWMYZSnih4r6KRyUPQgwd8GGc8GU7uFa8NYNwyCGU97pFz6meybl Mastodon: https://med-mastodon.com/@s4me/109931142704953144

What you need to know Tachycardia on standing or minimal exertion may occur after covid-19 and may cause substantial functional impairment When assessing a patient with tachycardia, consider potential causes including autonomic dysfunction Measures to reduce tachycardia can greatly improve...

Full title: Non-pharmacological interventions for self-management of fatigue in adults: An umbrella review of potential interventions to support patients recovering from critical illness Highlights • Self-management is effective for fatigue caused by physical conditions. • Self-management for...

Abstract Long-COVID syndrome is associated with high healthcare costs, but its pathophysiology is not yet fully understood. Inflammation, renal impairment or disturbance of the NO system emerge as potential pathogenetic factors. We aimed to investigate the relationship between symptoms of...

"2.1. Patients and Controls Patients were included in the study if they met all three of the most commonly used sets of ME/CFS diagnostic criteria (Fukuda et al. (1994) CFS criteria [12], the Canadian Consensus criteria of ME/CFS (2003) [13], and US Institute of Medicine, now called the...

Abstract Recent studies provide some evidence for the contribution of antibody-mediated autoimmune mechanisms to the nature of fibromyalgia (FM) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Much attention was paid to the autoantibodies (AAb) targeting G protein-coupled...

Abstract Objective The primary objective of this article was to systematically review the prevalence of somatic symptoms in patients, healthcare workers and general population during the COVID-19 pandemic. The secondary objectives were to record the association between somatic symptoms and...

Background Residual somatic symptoms (RSS) are common in depressed patients, predicting treatment effectiveness. However, sex differences in RSS have received little systematic study. This study was conducted to compare sex differences of RSS in patients with first-episode depression (FED)...

Correction: Defining the minimally clinically important difference of the SF-36 physical function subscale for paediatric CFS/ME: triangulation using three different methods The original article [1] required an amendment to the Quantitative Data statement in the Ethics Declarations section. The...