Upcoming symposium in Amsterdam on October 19 :https://turncovid.nl/covid-19-symposium/.
Presenters include: Michele van Vugt, Brent Appelman, Jeroen den Dunnen, Merel Hellemons and Rene Lutter as well as a humor section by the well known Hans Knoop.
Unraveling brain fog in post-COVID syndrome: Relationship between subjective cognitive complaints and cognitive function, fatigue, and neuropsychiatric symptoms
Abstract
Background and purpose
“Brain fog” is a frequent and disabling symptom that can occur after SARS-CoV-2 infection. However...
Indeed the monoclonal antibodies were adminstered in October and September 2021. The price of the drug doesn't seem to be too high either (at least compared to some other things) at roughly $1000 per person, from what I calculated. One would think they would have tried this on more patients by...
Influence of Prior SARS-CoV-2 Infection on COVID-19 Severity: Evidence from the National COVID Cohort Collaborative
Background As SARS-CoV-2 has transitioned from a pandemic to endemic disease, the majority of new infections have been among previously infected individuals. To manage the risks...
A couple of months ago I read this news article https://www.news-medical.net/news/20230804/Genetic-reasons-behind-Raynauds-phenomenon-discovered.aspx. I suppose there would naturally be a significant overlap in the findings since there are overlaps in the biobanks. The news article also states...
Limitations and criticism of the HopeBiosciences trial can be found here: https://www.s4me.info/threads/usa-texas-long-covid-stem-cell-trial-hope-biosciences.33379/#post-475832.
Adipose-derived, autologous mesenchymal stem cell therapy for patients with post-COVID-19 syndrome: an intermediate-size expanded access program
Abstract
Background
Evolving mutations of the novel coronavirus continue to fuel up the pandemic. The virus affects the human respiratory system along...
Similar to a previous study HERV-W and HERV-K again don’t seem to play a major role in ME/CFS (here they even seem to be downregulated in ME/CFS, FM and other comobidities). On the other hand a larger role was suggested in Covid and Long Covid...
Indeed the authors are not making this claim (I also wasn't trying to suggest that they were even though my post does definitely read that way), but I doubt the media or someone reading an article on it will interpret it that way. The question for me is what is the point of studying this so...
The problem is that the above research doesn't at all even try to look at longlasting Long-Covid or even anything related to ME/CFS (it essentially just looks at predominantly older patients to see whether someone had a cough or something else 4 weeks out). Whether the viruses that causes ME/CFS...
Virtual reality for assessing stereopsis performance and eye characteristics in Post-COVID
Abstract
In 2019, we faced a pandemic due to the coronavirus disease (COVID-19), with millions of confirmed cases and reported deaths. Even in recovered patients, symptoms can be persistent over weeks...
In my eyes this study would only be interesting if they would look at those patients with a low HRQoL (or multiple severe symptoms) multiple months post infections via a follow-up. The common long cold symptoms of cough, stomach pain and diarrhoea 4 weeks out are very uninteresting and mind I...
Apparently there is now also an Austrian Biobank setup by the WE&ME Foundation (formerly TEMPI Stiftung) https://www.weandmecfs.org/research/me-cfs-biobank-austria-establishment-of-the-first-austrian-biobank-for-me-cfs-patient-samples.
Some of the other work by this group has now been added to the forum (there are more papers for instance 1, 2, 3, from this group on this topic, but I don't want to spam this forum with too much of this mishmash of results, as these papers should give the insight needed on the type of work this...
Increased insulin resistance due to long COVID is associated with depressive symptoms and partly predicted by the inflammatory response during acute infection
Objective:
Some months after the remission of acute COVID-19, some individuals show depressive symptoms, which are predicted by...
Lowered oxygen saturation and increased body temperature in acute COVID-19 largely predict chronic fatigue syndrome and affective symptoms due to Long COVID: A precision nomothetic approach
Background: Long coronavirus disease 2019 (LC) is a chronic sequel of acute COVID-19. The exact...
Brain-targeted autoimmunity is strongly associated with Long COVID and its chronic fatigue syndrome as well as its affective symptoms.
Abstract
Background:
Autoimmune responses contribute to the pathophysiology of Long COVID, affective symptoms and myalgic encephalomyelitis/chronic fatigue...
Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19
Highlights
Longitudinal proteomics reveals aberrant complement patterns in severe COVID-19
Human PSC-vascular organoid models endotheliopathy by SARS-CoV-2 infection
SARS-CoV-2 spike-ECD triggers...
Referencing Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19, which is discussed here https://www.s4me.info/threads/complement-factor-d-targeting-protects-endotheliopathy-in-organoid-and-monkey-models-of-covid-19-2023-kawakami-et-al.35564/.
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