Search results

I find it a bit frustrating that there may be potential with the supplements but the studies are not good enough to say anything. I see no point in doing such small open label studies especially when measured with a questionnaire.

I was assuming it related to one of the PACE supporters (and Sharpe) celebrating the Rituximab failure.

Not sure about this one as it appears to be open label and assessment via the CFQ. But it is another paper looking at supplements for mitochondria and could relate to this paper https://www.s4me.info/index.php?threads/a-novel-nutriceutical-treatment-of-me-cfs-frank-comhaire-sept-2017.1036/

It is but I think it is noticeable that F&M have a huge amount of integrity in how they have handled this especially in comparison to others.

I view their approach as hate speech and I think they should be reminded of this. I say that because it is designed to label a whole group (and a minority) with a stigmatizing label (of dangerous and aggressive). The approach to me is to remind them of that. The way they talk about people with...

I had thought that the sickness behavior theories initially came from Vets looking at the behaviour of animals when sick.

I wondered about that. The recruitment strategy may play a big part as well. If I remember correctly the phase 2 trial recruited from the neurology department.

If that is what they are measuring rather than group means. If the numbers of responders are low then there may not be sufficient power to make them statistically significant. But there could be a small number with really significant improvements. Then the question is why - it wouldn't suggest...

I think there is another issue which is the branding of actions from possibly a few individuals to a whole group. Its an action that increases prejudice and would not be acceptable for any other group. Its basically building a stereotype that PwME are aggressive and violent.

It would depend on the size of the response. If 30% improved massively that would be good but if it was just a small improvement then that would seem less interesting. What seemed interesting from the previous trial was the amount of improvement that some people got but I think the numbers for...

It will still be interesting to see their results and they seem to have done a lot of blood analysis along the way, I'm wondering if they had no real improvements or good improvements in the placebo group.

Talking to people who have worked on anti-counterfeiting there are a lot of issues with fake drugs.

Clearly there is no simple rule. But if someone has a big audience they have a duty to get things right or at least understand the issues so should be able to defend their statements and views. Sometimes I think I rely on other people to point out my wrong or impractical ideas. I value and...

I do think some people (including myself) think different amounts of criticism should be given according to the status of the person. So I think a senior academic such as a professor should be able to justify everything they do. But with a junior researcher or a PhD student I sometimes think...

I agree rather than speculating about motivations we can look at the detail of the work. I find motivations very hard to understand. As someone with no great career motivation I am constantly surprised by people who do stuff to help their career rather than because its fun, interesting or just...

But we should remember that Crawley is quick to attack work she does not agree with. I'm not sure what the 'soft' sciences are but I've seen vigourous debate between psychologists and economists. I think some academics feel threatened by questioning and transparency from those outside of their...

I was assuming that if certain foods/supplements had an effect it would be by rebalancing a process within the body. Hence, wouldn't be expected to cure but may alleviate symptoms. Which is why I was interested in the comment in the paper around the improvements being maintained and whether...

I think there have been a few approaches to this and I do wonder if they have potential. Basically looking at the cycles that appear to be going wrong and trying to support them. I thought that at one point Ron Davis and Naviaux had been suggesting such approaches although I think with no...

I was wondering if more measurements than just the FSS scale were being used. One of the issues that has been raised with other open label trials is the use of subjective measurements. It would be good to see more objective activity data being measured to get a better picture of the effects. I...