Search results

Yes, agreed. But, in the case of people with Long Covid ME/CFS, there is a better alternative to the FND diagnosis - ME/CFS. Of course, plenty of health professionals think ME/CFS is an FND, but at least there is the NICE ME/CFS Guideline saying not to use the Lightning Process and GET. I...

From that Plasma ceramide paper - it looks as though things are more complicated than high or low. Drawing conclusions based on total ceramides might not be a good idea.

Thanks for posting this @SNT Gatchaman. It sounds as though ceramide levels in plasma might be changed by diet and exercise. Plasma Ceramides Pathophysiology, Measurements, Challenges, and Opportunities But, high levels of ceramides in the plasma sounds to be problematic, rather than lower...

Gosh, I have 13 posts that have appeared in my night that I multiquoted, wanting to respond to them. A lot of the responses I wanted to make, such as pointing out the temporal aspect of some lesions as in MS that can make them difficult to identify, other people have already made beautifully...

Member @Mike Harley will be in Serbia soon raising funds for ME/CFS Research. Here's a pre-marathon interview with a person with ME/CFS in Serbia: Mike's EU Marathons

Thank you very much Mike, the interviews are always interesting to read.

If the "clinical toolkit" was actually just a survey asking users of NHS ME/CFS services if they felt the service was useful, if they felt that they had been treated with respect and asking for ideas for improvements, that would be fine and useful. But, that would not be clinical toolkit. And...

From the above article: What's with this 'gold-standard' stuff? It's like it is from a BPS playbook - someone has said 'how can we convince people that we are really right?' and someone else has said 'keep repeating 'gold standard''. Sensitivity is the test's ability to identify an individual...

Can anyone recall that pie chart posted recently with the diagnoses that people with Long Covid were getting? From memory, there was a really small percentage of Long Covid people being diagnosed with ME/CFS - 6%? And a large percentage of people being diagnosed with FND.

But things are not as clear cut as that. There are papers that throw a lot of doubt on the accuracy of diagnoses of psychogenic seizures. And, in a post further back in this thread, I referred to a paper on neurogenic stuttering: Neurogenic Stuttering: Etiology, Symptomatology, and Treatment...

:) And yet there they are. In the industry I used to work in, we were under no illusions that some of the people who worked in the industry were inexperienced, lacked knowledge, over-worked, under the influence of drugs and/or at the best of times could not think at the level needed to work...

:laugh: You and I seem to be going through a period of disagreement Jonathan. I like the idea of this - a checklist to guide inexperienced editors checking a study. If editors had to go through a checklist and then followup on items that are red flags, then some of the shockingly bad papers we...

I'm surprised that there is nothing there about conflicts of interest of the authors. That is something we have seen a lot of on the forum - for example, the people with financial interests in a chain of hyperbaric oxygen clinics find that hyperbaric oxygen treatment solves all the problems.

A summary of the red flags suggesting further enquiry - the actual items are a bit more defined than I have summarised them as, making it easier to say 'yes' or 'no'. Governance No registration of the trial before the trial starts Discrepancy between planned and actual sample size Issues with...

This appears to be the main link with Cochrane Also one of the authors is a member of a Cochrane group.

Abstract Objectives: To propose a checklist that can be used to assess trustworthiness of randomized controlled trials (RCTs). Design: A screening tool was developed using the four-stage approach proposed by Moher et al. This included defining the scope, reviewing the evidence base, suggesting...

More from this team here: Who Cares About Publication Integrity?, 2022, Grey, Avenell & Bolland

Thanks @Deanne NZ. Great, SNT. Could also provide material about the Cochrane Exercise Review, especially given at least a couple of Cochrane Officers also work at Auckland University

It's useful to see what authorities think FND is. Mayo clinic https://www.mayoclinic.org/diseases-conditions/conversion-disorder/symptoms-causes/syc-20355197 NINDS at NIH https://www.ninds.nih.gov/health-information/disorders/functional-neurologic-disorder The entry on wikipedia is really...