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Published papers thread for w/c 4th Dec Facebook: https://www.facebook.com/sci4me/posts/pfbid02Tkvdf3TLLo4WrC9ehMoNza4hA6aioa98go6nioFSQRFYiA42P49nGCtYZvUkXdbKl Mastodon: https://med-mastodon.com/@s4me/111561149320261071

Objectives This study aimed to assess the psychometric properties of two widely used fatigue scales in a sample of patients with inflammatory conditions. Methods Rasch analysis was used to examine scale reliability, item bias, unidimensionality and overall fit to the Rasch model. Sub-test...

New menopause therapy guidance will harm women’s health, say campaigners New official guidance on treating menopause will harm women’s health, experts, MPs and campaigners have warned. Last month, new draft guidelines to GPs from the National Institute for Health and Care Excellence (Nice)...

News in Brief posts for w/c 4th December. Facebook: https://www.facebook.com/sci4me/posts/pfbid02QeWZGEdegEd5dW1ozoAPAdocJWXDGdptxeo8pYceRkdQXJm1N5BJ2htMqHEFU8mql Mastodon: https://med-mastodon.com/@s4me/111555826342374409

Published as An Explainable Artificial Intelligence Model Proposed for the Prediction of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Identification of Distinctive Metabolites Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and...

Background: The lower Saint Lawrence river region (LSLRR), in Quebec, has a 10-fold higher incidence of Q fever compared to the provincial rate. This study aimed to review clinical cases and the Q fever risk exposure in this region. Methods: Data were retrieved from microbiology laboratory...

Abstract Mitochondrial dysfunction alters cellular metabolism, increases tissue oxidative stress, and may be principal to the dysregulated signaling and function of CD4+ T lymphocytes in the elderly. In this proof of principle study, we investigated whether the transfer of functional...

Moved from the general Long Covid news thread Opinion piece in the BMJ Hancock’s covid inquiry evidence offers few clues as to why long covid was sidelined Questions remain as to why long covid wasn't a political priority, writes Ondine Sherwood In the early weeks and months of the covid-19...

Copied from UK news Opinion piece in the BMJ Hancock’s covid inquiry evidence offers few clues as to why long covid was sidelined Questions remain as to why long covid wasn't a political priority, writes Ondine Sherwood In the early weeks and months of the covid-19 pandemic, it was left to...

So how do you then suggest we study it? Please could you describe how "PVFS with delayed symptoms" was different to "ME/PEM"?

So in all of this talk, of claiming to 'demystify' LC, has there been any mention of ME/CFS? And what she doesn't say is that some of her colleagues in the research and medical systems will be the ones taking advantage of the uncertainty, by making up such things as the deconditioning model for...

Full title: Implications of the quality of the doctor-patient relationship on health in adult ME/CFS patients. A qualitative public health study from a patien [sic] perspective Background: Most patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are dissatisfied with...

I'm of the opinion that basing research strategy on individual anecdotes or assumptions, especially when they run counter to the experiences of so many other people, is not what we need to do at this time. If PEM is to be researched, and it should be, then lets research PEM, then we can...

The process of measuring what ends up being up PEM when we go beyond our limits certainly could start before the patient participants experience symptoms, but without evidence that the process ends up being PEM then claiming the process is PEM could well be misleading. In most case definitions...

I think that most of us identify PEM as being something that occurs when we have gone beyond our limits, so it would be hard to study PEM without doing so.

From DecodeME social media channels. "Join us for our #DecodeME December Webinar next Thursday for project updates, 2nd questionnaire info and ‘what is happening to your data?’. Email contact@decodeme.org.uk with any questions you have for Sonya, Chris and Andy. To sign up...

9,601 signatures at time of posting. https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

Is AI leading to a reproducibility crisis in science? "During the COVID-19 pandemic in late 2020, testing kits for the viral infection were scant in some countries. So the idea of diagnosing infection with a medical technique that was already widespread — chest X-rays — sounded appealing...

I would argue that energy impairment will impact on all of that.

Sex is an exertion, just like walking, concentrating, or anything else that might require a certain level of energy. So if someone has a condition that reduces their energy levels, that will have an impact on their sexual function. So no surprises but important that is is investigated, and I'm...