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Abstract The willingness to exert effort for reward is essential but comes at the cost of fatigue. Theories suggest fatigue increases after both physical and cognitive exertion, subsequently reducing the motivation to exert effort. Yet a mechanistic understanding of how this happens on a...

The 12th Oct webinar recording and transcript is now available, https://www.decodeme.org.uk/webinar-recording-and-transcript-initial-questionnaire-analysis-decodeme/

Chris and Sian will be speaking to Edinburgh Medical School on Instagram Live on Weds 18th, 11:30am BST.

‘My self-worth plummeted every month’: the hidden disorder that can ruin women’s lives "By the time Emily got her diagnosis, she was under 24-hour supervision by her mum, suffering with anorexia and routinely self-harming. Her suicide attempts had numbered “too many to count”. She had seen...

Introduction Major traumatic injury is associated with early hemorrhage-related and late-stage deaths due to multiple organ failure (MOF). While improvements to hemostatic resuscitation have significantly reduced hemorrhage-related deaths, the incidence of MOF among trauma patients remains high...

Highlights Fatigue is a symptom with a serious impact on patients’ quality of life. Inclusion of fatigue as an RCT outcome is crucial to understand the impact of DMTs. Limited RCTs of DMTs assessed fatigue as an outcome. The reporting of PROs of DMT trials assessing fatigue is suboptimal...

Latest forum social media posts. Facebook: https://www.facebook.com/sci4me/posts/pfbid02AvmsPRwNHWTTijWwWEZfduAoqZotN6coZDL1ARpJKeAW3HuZBW94YtuEHaU1aa8bl Mastodon: https://med-mastodon.com/@s4me/111243722241034683

8,597 signatures at time of posting. https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

Published papers from w/c 9th Oct. Facebook: https://www.facebook.com/sci4me/posts/pfbid02aVeX8nZVvPPKMHizudhW3ofJaZiYnGEYqYd8xmKxmceMtPEDUyp2KgG1Jvqtato1l Mastodon: https://med-mastodon.com/@s4me/111243588397803713

Full title: The Impact of Depression, Anxiety and Personality Disorders on the Outcome of Patients with Functional Limb Weakness – Individual Patient Data Meta-Analysis Objective Psychiatric comorbidities such as depression, anxiety, and personality disorders are common in patients with...

News in Brief posts for w/c 9th Oct. Facebook: https://www.facebook.com/sci4me/posts/pfbid0DXNisfLYG88kkDcPqFk6QM8EaBghQSNdSxP6dPrLN2tMAtAKeuAFxyxkp4tTVGuYl Mastodon: https://med-mastodon.com/@s4me/111239003056492168

Peer review record is here, https://www.mdpi.com/2624-8611/5/4/73/review_report

Abstract A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2...

Abstract Background Postacute sequelae of COVID‐19 (PASC) and HIV are both associated with reduced exercise capacity, but whether SARS‐CoV‐2 or PASC are associated with exercise capacity among people with HIV (PWH) is unknown. We hypothesized that PWH with PASC would have reduced exercise...

ABSTRACT Background and Research Question: The SARS-CoV-2 pandemic often resulted in prolonged illness courses. A particular challenge today lies in the clinical presentation resembling that of Myalgic Encephalitis/Chronic Fatigue Syndrome (ME/CFS). Method: We review selected literature...

Trial By Error: Authors of Dutch Long Covid Paper Contradict Each Other https://virology.ws/2023/10/14/trial-by-error-authors-of-dutch-long-covid-paper-contradict-each-other/

Given that a couple of authors are based at Aarhus I'm surprised that they reported the negative association.

"According to CDC-1994 criteria, 80.4% of the participating mothers have CFS (n=45), and 19.6% have not (n=11)."

"Researchers have created the largest atlas of human brain cells so far, revealing more than 3,000 cell types — many of which are new to science. The work, published in a package of 21 papers today in Science, Science Advances and Science Translational Medicine, will aid the study of diseases...

I had a quick look to see if I could find a recording, sadly I couldn't. What I did find though was a session from the recent "Cochrane London" event entitled "Building trust through co creation: re-imagining evidence".