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From "Dr. T", "If your GUT (enteric nervous system barrier) or BBB (blood-brain-barrier) is compromised you can make REALLY IMPACTFUL changes in as little as a few months. Heal leaky gut w/ BPC-157 and gut-brain axis with ProdromeGlia and ProdromeNeuro." No need to bother with expensive and...

3,250 signatures at time of posting. https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

Funnily enough I was talking with my wife about how I feel, and I was describing that, even before I do anything else, I feel a lack of a large part of my energy, which in itself is a weird thing to me - 40 years ill and I still feel as if I am missing energy, I would have thought I would have...

Abstract Objective Hypophosphatasia (HPP) is a rare disease characterized by incomplete or defective bone mineralization due to a mutation in the alkaline phosphatase (ALP) gene causing low levels of ALP. Disease presentation is heterogeneous and can present as a chronic pain syndrome like...

From the bottom of the document. "This Easy Read booklet was produced by easy-read-online.co.uk The booklet includes images licensed from Photosymbols & Shutterstock. "

Full title: Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation Abstract When high-intensity exercise is performed until exhaustion a “functional reserve” (FR) or...

Bias shown in only the second paragraph. "While some recommendations suggest that PA might reduce fatigue symptoms32,33,34,35, other studies indicate limited or no effects of exercise therapy on fatigue among adults with chronic fatigue syndrome36 and Parkinson’s disease37. Nevertheless, PA...

Well, this is a crap explanation. (Click to expand)

From an email. "Easy-read versions of the ME/CFS Interim Delivery Plan and Consultation are now available at the following link: https://www.gov.uk/government/consultations/our-plan-to-improve-the-lives-of-people-with-mecfs-easy-read The easy-read consultation is open for 8 weeks, closing 30...

New social media posts for easy sharing. Facebook: https://www.facebook.com/sci4me/posts/pfbid0bB3ujPACo4UT3Hmyi24gLaSE15cSyYqKK75QAkEuJnhLSQSHaLkFijTv8pfWD6afl Mastodon: https://med-mastodon.com/@s4me/111011589437964113

"Is there no mercy in this world for those of us forced by professional obligations to read this unceasing stream of sewage?" You absolutely have my sympathy but just think what it is like then for those of us who don't even have professional obligations, but are forced by a potentially...

2,218 signatures at time of posting. https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

Medical-evidence giant Cochrane battles funding cuts and closures "This month, more than 1,000 people will gather in London for a meeting of Cochrane, the group known for its gold-standard reviews of evidence in medicine. The conference marks the 30th anniversary of an organization that helped...

ME Research UK and Daphne Jackson Trust launch ME/CFS Fellowship "Applications are invited for a three-year Daphne Jackson Fellowship co-sponsored by ME Research UK. The Fellowship is open to talented researchers with a PhD – likely in a life science e.g. biomedical sciences, whole organismal...

Published papers thread for w/c 28th August. Facebook: https://www.facebook.com/sci4me/posts/pfbid06UUDb5rEkGXuFgdkaFAxz7unb2qHUZXXLze8s3VcQJ4rqkostVDZoH6wVhL9u1vTl Mastodon: https://med-mastodon.com/@s4me/111006223930043318

UK’s Long Covid research under threat from regulator backlog, warn scientists "Scientists are warning that delays at the UK’s medicines regulator mean an important trial looking for ways of treating Long Covid risks running out of money before it finishes. Researchers hunting for treatments...

Thanks. In the consultation the figures listed are, since 2013, MRC, £4.15 million (including £3.19 million for DecodeME), and NIHR, £3.9 million (not including DecodeME). Looking at the figures from CRG that you link to suggests that none of that spending resulted in evidence of any use in the...

News in Brief for w/c 28th August. Facebook: https://www.facebook.com/sci4me/posts/pfbid0GVuQCrRFYe144J1wzEtyBfdLrENtZYcywxfEkJYhVRv5GZV471cQskB79jGSsPt8l Mastodon: https://med-mastodon.com/@s4me/111000988997188106

Seems a bit odd that a Phase-2B Randomized Placebo-Controlled Trial of Inebilizumab in Anti-NMDA Receptor Encephalitis, https://n.neurology.org/content/98/18_Supplement/1651, is sponsoring a podcast episode about FND.

PODCAST: An Updated Round Table Discussion on FND: How and Why Does FND Occur? "In the second episode of our three-part series, Prof. Jon Stone talks with Drs. Selma Aybek, David Perez, and Sarah Lidstone about how and why FND occurs. Associated Links: FND Society at fndsociety.org FND guide...