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  1. Andy

    Functional Neurological Disorder (FND) - articles, social media and discussion

    PODCAST: An Updated Round Table Discussion on FND: Diagnosis of FND and New Phenotypes "In this first episode of our three-part series, Prof. Jon Stone talks with Drs. Selma Aybek, David Perez, and Sarah Lidstone about FND diagnosis and exploring new phenotypes. Associated Links: FND Society...
  2. Andy

    Persistent Neurological, Dissociative, and Amnestic Symptoms Following a Mild Traumatic Brain Injury in an Adolescent: ... 2023 Leczycki et al

    Full title: Persistent Neurological, Dissociative, and Amnestic Symptoms Following a Mild Traumatic Brain Injury in an Adolescent: A Complex Case of Conversion Disorder Abstract The diagnosis of conversion disorder may be given to patients with unexplained neurological symptoms after the...
  3. Andy

    ‘She thought the same way I that I thought:’ a qualitative study of patient-provider concordance among Gulf War Veterans with GWI 2023 Lesnewich et al

    And then that trust will be lost once the patients figure out that the provider's expertise is illusionary and their theories are disguised patient blaming.
  4. Andy

    ‘She thought the same way I that I thought:’ a qualitative study of patient-provider concordance among Gulf War Veterans with GWI 2023 Lesnewich et al

    Objective: Medically unexplained symptoms (MUS), such as chronic fatigue syndrome, irritable bowel syndrome, and Gulf War Illness (GWI), are difficult to treat. Concordance—shared understanding between patient and provider about illness causes, course, and treatment—is an essential component of...
  5. Andy

    Analysis of research funded by UK bodies and assessed in the NICE guideline process?

    A thought inspired by the currently ongoing UK consultation on ME/CFS - has anybody compared the research funded by the UK funding bodies since 2013 and assessed in the NICE guideline process to see the quality of evidence provided by those studies? My immediate assumption is no. In the...
  6. Andy

    United Kingdom: ME Research UK (MERUK) News

    Latest funded project. Investigating spinal nerve cell function and the serotonin system in ME/CFS Researcher Prof. Janet Taylor Institution Edith Cowan University, Australia https://www.meresearch.org.uk/research/taylor-064/
  7. Andy

    Hypothesis Long COVID as a functional somatic symptom disorder caused by abnormally precise prior expectations during Bayesian perceptual processing, 2023, Joffe

    I wonder how the authors believe they themselves are resistant to "Pandemic-Response Syndrome", especially as in writing this piece of absurd fiction scientific paper they have exposed themselves to far more concepts of and writings about Long Covid than the average member of the public would...
  8. Andy

    Hypothesis Long COVID as a functional somatic symptom disorder caused by abnormally precise prior expectations during Bayesian perceptual processing, 2023, Joffe

    Abstract This review proposes a model of Long-COVID where the constellation of symptoms are in fact genuinely experienced persistent physical symptoms that are usually functional in nature and therefore potentially reversible, that is, Long-COVID is a somatic symptom disorder. First, we...
  9. Andy

    Short- and mid-term outcomes of multisystem inflammatory syndrome in children: a longitudinal prospective single-center cohort study 2023 Roge et al

    From the discussion. "According to our data, at the 2-week follow-up, almost half of the children (N = 10, 47.6%) experienced exercise intolerance with secondary-induced tiredness after any physical activity. Additionally, three children (14.3%) could not walk for more than 15 min or climb the...
  10. Andy

    Short- and mid-term outcomes of multisystem inflammatory syndrome in children: a longitudinal prospective single-center cohort study 2023 Roge et al

    "Two weeks outcome All children were examined 2 weeks after the MIS-c diagnosis was established. The patients were hemodynamically stable during the evaluation and showed significant clinical improvement after receiving immunomodulatory therapy. However, the most persistent complaint was...
  11. Andy

    Short- and mid-term outcomes of multisystem inflammatory syndrome in children: a longitudinal prospective single-center cohort study 2023 Roge et al

    Background: Multisystem inflammatory syndrome in children (MIS-c) emerged during the coronavirus disease 2019 pandemic and is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite the extensively studied clinical manifestation of acute condition, the short- and...
  12. Andy

    Functional Neurological Disorder Overlapping Paroxysmal Kinesigenic Dyskinesia Confirmed by Genetic Diagnosis 2023 Ohira et al

    Functional neurological disorder (FND) may mimic various kinds of neurologic diseases and may coexist with other neurologic disorders. In cases overlapped by FND, it might be challenging to distinguish symptoms induced by FND and those induced by other underlying neurological disorders...
  13. Andy

    International: Science for ME social media posts

    Reddit thread for the August News in Brief. Copy and paste https://www.reddit.com/r/cfs/comments/1671l27/news_in_brief_posts_for_august_2023_covering/
  14. Andy

    Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells 2023 Sanmarco et al

    Dendritic cells (DCs) have a role in the development and activation of self-reactive pathogenic T cells1,2. Genetic variants that are associated with the function of DCs have been linked to autoimmune disorders3,4, and DCs are therefore attractive therapeutic targets for such diseases. However...
  15. Andy

    Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection 2023 West et al

    Highlights CD4+ T cell-intrinsic arginase 1 controls Th1 induction and contraction kinetics Loss of arginase 1 in CD4+ T cells results in reduced Th1-mediated tissue pathology Th1-intrinsic arginase 1 ensures balanced glutamine vs. arginine metabolism CD4+ T cell-intrinsic arginase 1 and 2 have...
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