Search results

Lactate is a glycolysis product that is produced from pyruvate by LDH (lactate dehydrogenase) and plays an important role in physiological and pathological processes. However, whether lactate regulates autophagy is still unknown. We recently reported that LDHA is phosphorylated at serine 196 by...

I did need to boost the volume a bit in order to him clearly, it was OK for me but it might be challenging for others with more sensitive hearing than me.

David Tuller: Interview about DecodeME with Professor Chris Ponting "Professor Chris Ponting is a geneticist at the University of Edinburgh. He is also the principal investigator for DecodeME, a genome wide association study. The DecodeME team recently published findings from more than 17,000...

From an email from IACFSME. 2023 IACFS/ME Conference: Video Recordings Now Available for Purchase! The cost of one pass to the online video recordings is $300 USD for Non-Members and $250 USD for IACFS/ME Members. Your purchase includes: a. Unlimited, online access to all presentations...

As Patient and Public Involvement (PPI) in research becomes more widely accepted, and expected, by funders, there already is a growing need for PPI members with lived experience of ME/CFS, Long Covid and other related conditions. This thread is intended as a space where requests for PPI members...

I assume, but could not see confirmation, that this now supersedes this review, Cochrane Review: Psychological therapies for the management of chronic pain (excluding headache) in adults, 2020, C De C Williams et al.

Background Chronic pain (pain lasting three months or more) is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Common types (excluding headache) include back pain, fibromyalgia, and neuropathic pain. Access to traditional face‐to‐face therapies...

Preprint. Now published - see post #18 This is from Maureen Hanson's group. Abstract In healthy individuals, physical exercise improves cardiovascular health and muscle strength, alleviates fatigue, and reduces risk of chronic diseases. Although exercise is suggested as a lifestyle...

From an email. "We are excited to share the findings of a research project led by disabled women and funded by the British Academy and Leverhulme Fund. In 2022 Chronic Illness Inclusion collected testimonies of healthcare encounters from women, including trans women and non-binary people, with...

BACKGROUND:Functional neurological disorder (FND) may commonly co-occur with persistent symptoms following a psychological trauma or physical injury such as concussion. OBJECTIVE:To explore the occurrence of FND in a population with persistent post-concussion symptoms (PPCS) and the...

I think this is a step in the right direction, and I think that fatigability immediately after exertion being labelled as PEM, as per Jason et als PEM assessment tools and which I don't agree with, makes this necessary. I believe that fatigability immediately after exertion in pwME should be...

But I'm sure the 'proper' diagnosis should be "parasitic infection with FND overlay"... ;)

"Woman complained of forgetfulness and depression before doctors pulled out an 8cm roundworm normally found in pythons ... The patient, a 64-year-old woman from south-eastern New South Wales, was first admitted to her local hospital in late January 2021 after suffering three weeks of abdominal...

"Funding: The study was funded by a Medical Research Council Career Development Award to SP [MR/V032771/1]. This paper represents independent research part-funded by the National Institute for Health and Care Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation...

"Regarding state dissociation, only dissociative amnesia was elevated in the FND group compared to HCs. These results conflict with elevated trait-depersonalisation scores in this sample, and contrast with previous studies reporting elevations in both detachment and compartmentalisation...

Printed papers post for w/c 21st August. Facebook: https://www.facebook.com/sci4me/posts/pfbid0deYnPLV4H2KvyvVUiXBz7kNebTB44g48QXbMwTskEpavZDbYBGwX1x6WgZ1fWJ5ul Mastodon: https://med-mastodon.com/@s4me/110966272726539538

From an email I've received. We’re pleased to invite you to the Infection-Associated Chronic Conditions Patient Advocacy Coalition (IACCPAC) national webinar, a part of the IACCPAC Initiative, led by The Long Covid Alliance, Solve ME/CFS Initiative, COVID-19 Longhauler Advocacy Project...

News in Brief posts for w/c 21st August. Facebook: https://www.facebook.com/sci4me/posts/pfbid02P113D6DsP3xLHS2QVHvxmeWucS3WPYKoUToywCdGMCMAumRSKcdBoe1byy581F71l Mastodon: https://med-mastodon.com/@s4me/110961180525354743

Abstract Post COVID-19 Syndrome (PCS) is the persistence of symptoms after an infection with SARS-CoV-2 in both hospitalized and non-hospitalized COVID-19 survivors. Exercise was proposed as a rehabilitation measure for PCS and early studies focused on patients post-hospital discharge. The...

"This study found that young children who engaged in a variety of appropriate sports, such as exercising at least three times a week, sweating for at least 30 min each time, having a regular exercise habit, and engaging in a variety of sports, were low in fatigue symptoms. In addition...