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  1. Hutan

    Altered neutrophil proteomes in COVID19 patients ... associated with delayed recovery: ... PREDICT-COVID19, 2022, Long et al

    One of a small flurry of studies on neutrophils (Michael Van Elzakker and Ron Davis both have studies on neutrophils in ME/CFS underway); this one in Long Covid has results. A summary article from 2016 Neutrophil migration in infection and wound repair: going forward in reverse had this to...
  2. Hutan

    Altered neutrophil proteomes in COVID19 patients ... associated with delayed recovery: ... PREDICT-COVID19, 2022, Long et al

    https://thorax.bmj.com/content/77/Suppl_1/A2.1.abstract Abstract Introduction and Objectives Neutrophils are increasingly recognised for a role in acute COVID19, contributing to hyperinflammatory responses, immunothrombosis and tissue damage. However, less is known about the cellular changes...
  3. Hutan

    Neutrophil issues

    More on Dr Merete Long (the Dundee researcher) who was given an award for her work on neutrophils in Long Covid: https://www.dundee.ac.uk/stories/prestigious-award-university-researchers-covid-19-work PREDICT-COVID19, the study led by Merete, looked at cellular changes occurring within...
  4. Hutan

    Neutrophil issues

    :thumbup:
  5. Hutan

    Meditative-based diaphragmatic breathing vs. vagus nerve stimulation in the treatment of fibromyalgia—A randomized controlled trial 2022 Paccione

    That was interesting. I think there has been a lot of speculation about HRV's relationship with vagal activity. This trial should be a nail in the coffins of the ideas that meditation or diaphragmatic breathing help fibromyalgia. Good on the authors for devising a reasonable trial and for...
  6. Hutan

    Meditative-based diaphragmatic breathing vs. vagus nerve stimulation in the treatment of fibromyalgia—A randomized controlled trial 2022 Paccione

    This looks like a decent study - two treatments (vagus nerve stimulation and meditative breathing) each with a fairly reasonable sham version. So: None of the treatments changed heart rate variability None of the treatments performed better than the others with respect to pain Changes in heart...
  7. Hutan

    Neutrophil issues

    I'm not sure why Ron is making it sound as though a microfluidic device to assess neutrophil movement is a new thing, or why it needs to be developed. For instance, there was this 2013 paper: Measuring neutrophil speed and directionality during chemotaxis, directly from a droplet of whole blood...
  8. Hutan

    Neutrophil issues

    From what I can see, they are totally separate studies. Unfortunately Michael doesn't seem to be sharing exactly what they will be looking for, he says on twitter that he has learned to not openly share as much as he used to. He does say that some of the members of the team previously produced...
  9. Hutan

    Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian

    In the absence of any information at all, it's hard to be sure, but perhaps it is time for all of the people in the review writing group and on the IAG who want a scientifically based outcome to resign. The delay in any public progress is beyond reason and morality, as others have said...
  10. Hutan

    Blogs: Jennie Spotila - Occupy M.E.

    Nov 2022 New York Magazine Article Biased and Riddled with Errors Today I sent the following email to the Editor of New York Magazine: As a reader of New York Magazine, I have come to expect your articles to be accurate, well-researched, and fair. Unfortunately your recent piece, “Has Long...
  11. Hutan

    Paul Garner on Long Covid and ME/CFS - BMJ articles and other media.

    We also have evidence of his leaning to 'mind-body rubbish' prior to developing Long Covid. So perhaps we should see his sudden understanding that Long Covid could not be cured by positive thinking and exercise as the aberration in his thinking. When he began to naturally recover, he could...
  12. Hutan

    Susceptibility-Weighted Magnetic Resonance Imaging Highlights Brain Alterations in COVID Survivors, 2022, Mishra et al

    It's not clear from the article or the abstract how many, if any, of the study participants had Long Covid. If it's a general post-Covid effect that doesn't correlate with Long Covid symptoms, it might still be a clue, but there's a need to explain what is different about people with Long...
  13. Hutan

    Fibromyalgia and nonfibromyalgia chronic pain: Differences in psychological characteristics and treatment outcomes, 2022, Salaberria et al

    Yes, that was one good thing, the study is evidence that CBT doesn't help fibromyalgia. But of course, in the BPS world, that just means more funding is needed to tweak the CBT offering to make it more suitable and/or study the application of some other psychological treatment with a...
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