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  1. Jonathan Edwards

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    I don't think it is saying anything particularly unexpected or surprising. Cord damage is likely to be a mixture of pressure and tension. That does not change the way we understand the clinical picture. Also he is talking about cervical myelopathy from narrowing in the lower cervical region...
  2. Jonathan Edwards

    Psychometric properties of the PROMIS® Fatigue Short Form 7a among adults with [ME/CFS], 2019, Yang et al

    I cannot se any point in these composite score systems unless it is specified exactly what they are to be used for. Are they to judge a current state, or make diagnosis, or measure a change with time or treatment? You want different measures for each, and for treatments very likely different for...
  3. Jonathan Edwards

    Functional neurological disorder: an ethical turning point for neuroscience, 2019, Edwards

    This is the citation point: Another answer is that the available evidence indicates that specific treatments for FND coupled with careful selection of patients work well: effect sizes are often very large when judged by the standards of drug trials for similarly disabling neurological disorders...
  4. Jonathan Edwards

    Functional neurological disorder: an ethical turning point for neuroscience, 2019, Edwards

    Oh but he does - if you look at the citations. Basically he is echoing Wessely's concern that all his patients will be sent off to cheap services instead of what ought to happen - imply an expensive multidisciplinary team and get them to decide to send the patient to trudge Chalder (or her...
  5. Jonathan Edwards

    A study I want someone to do

    Yes, those sorts of things sound interesting. Failure of habituation at a low electrophysiological level would be very interesting.
  6. Jonathan Edwards

    Trial By Error: An Open Letter to Dr Godlee about BMJ’s Ethically Bankrupt Actions

    You need to multiply that be the number needed to treat though, and the amount of benefit in terms of Quality Adjusted Living Death Years
  7. Jonathan Edwards

    Elsevier investigates hundreds of peer reviewers for manipulating citations

    It is blackmail. If you refuse to cite a paper the reviewer just says he thinks that changes are not adequate and recommends rejection. A good editor can keep tabs on that sort of behaviour but the author has no way of knowing whose side the editor is on. I am now lucky that my salary does not...
  8. Jonathan Edwards

    Elsevier investigates hundreds of peer reviewers for manipulating citations

    Why don't they remove the citations and blacklist the reviewers? This practice has been going on ever since I have been in science. The easiest way to tell who has reviewed your paper is by what papers they require you to cite in order to satisfy their comments. It happened to me a couple of...
  9. Jonathan Edwards

    Dogs Are Dying Suddenly in Norway

    Maybe someone in Oslo has an auntie in Tromso.
  10. Jonathan Edwards

    Dogs Are Dying Suddenly in Norway

    Are you suggesting that viruses buried in the permafrost might with climate change be released to cause pandemics amongst populations that have no immunity?
  11. Jonathan Edwards

    A study I want someone to do

    Not the ones I know. Or the ones with small cardiac volumes in the various studies.
  12. Jonathan Edwards

    Dogs Are Dying Suddenly in Norway

    Yup. And a dog dropped dead on Hampstead Heath yesterday - no kidding. All very worrying.
  13. Jonathan Edwards

    A study I want someone to do

    It think it is very possible that signals derived from events in the rest of the body, like immune responses, could alter the ability of neurons to carry out the processes of thinking. The problem with metabolic suggestions involving oxygen or waste products is that: 1. these ought to have been...
  14. Jonathan Edwards

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    A very interesting question. So to answer it we want to know what limits toe-touching. Toe-touching, or more than that, palm to floor touching, is one of the criteria for hypermobility and is usually assumed to be a sign of lax ligaments. But toe or floor touching is, I suspect, almost...
  15. Jonathan Edwards

    UK: London GP's told to restrict specialist referrals under new NHS 'rationing' plan (The Guardian, 8 Sep 2019)

    Do you get manunsplaining and womanunsplaining? And what would that be in German or Norwegian?
  16. Jonathan Edwards

    A study I want someone to do

    I think I agree Trish, but I get stick for doing so. Ordinary people think brains think but Gilbert Ryle the philosopher said that was a category mistake, only people think. I won't go on about it but my reasoning is given in an essay called 'Giving Descartes His Due' in a monograph by Hackett...
  17. Jonathan Edwards

    A study I want someone to do

    Indeed. I said a clue! I don't remember bringing in psychological accounts - I was responding to you bringing them in with 'people'. I still don't know what that can mean in biological terms. The event domain of thinking is smaller than the brain, not larger. For sure, antecedent events in...
  18. Jonathan Edwards

    A study I want someone to do

    Hi @Woolie. I don't buy it. But I realise my disagreement is not a personal one. Asim Roy and I co-edited a volume of Frontiers in Psychology recently on representation in the brain where we tried to make the case for the neuronal level being central to understanding brain and thought, hoping...
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