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I think distraction might be different concepts in the two papers? In the one here, the idea seems to be that people with fatigue can think about other things and that distraction will result in less fatigue. Whereas in that linked paper about MS and LC, I think they are suggesting that...

I think that ambiguous title just means that the reported level of cognitive fatigue negatively correlates with performance on a couple of specific cognitive function tests (more reported cognitive fatigue = a reduced performance) in MS but not in Long Covid. However, I don't think it can be...

From the article: From what is written the article, I have a bit of doubt that miracle cures have been found, but at least now people are looking for them.

From the Quadram Website: As far as I can tell from an internet search, red light penetrates at most 2 mm into skin. From the picture in the tweet above, the participants are fully clothed, and there is just one light shining onto a masked face. The description of the therapy is that the...

Coming back to this, this morning, I'm still incredulous. Very nice examples @rvallee. I loved the jam one. But what these people did is actually far worse. It's like the participants in the food company test don't actually get to see and taste and smell the jams. Instead they only get a...

I haven't read the study. But the first point is the bias in the selection of respondents. 'International online' suggests a lot of self-selection. The second point is that if I had to do this and the options were A. CBT or psychotherapy B. Short or long C. Online or in a clinic I too would...

They are actually calling for more objective measurement of cognitive dysfunction: So, all up, this paper could be worse. I'd go so far to suggest it is an anomaly :) - a paper with Chalder as an author that is not dreadful. Of course, a big problem, and they acknowledge this, is that they...

Gosh, there is entertainment of the possibility of physical damage: But, of course, it could just be due to the behavioural issues: Interesting that the words 'deep phenotyping' are used: An acknowledgement that their data collection approach needs improvement:

That must have challenged Chalder's story-making ability. Somehow the young people who developed brain fog on reinfection had managed to not develop brain fog during the first Covid-19 infection. 75% of the first positives are female; 66% of the reinfected are female Index of multiple...

Out of the 163 people with a pre-pandemic sample, 82% had no post-Covid syndrome. 10/163 (6%) had fatigue at 6 months after infection; 5/163 (3%) had fatigue at 12 months after infection

That's a confusing long sentence, but there is a good point in there - that DNA sequencing of family members of the patient would be interesting. I have the feeling that mitochondrial DNA has been looked at, and nothing of significance has been found. But, perhaps it is worth looking again...

It's a clear read, so far. It's certainly not the first time that it has been proposed that problems with complex IV and complex V of the electron transport chain. The onset following a triggering EBV infection seems quite clear. That association of elevated EBV antibodies with ME/CFS crashes...

good points

Imaging glial activation in patients with post-treatment Lyme symptoms; pilot using CDPA-713 PET, Pomper et al, 2018

(paragraph breaks added for readability; it is just one paragraph) Some comments about the introductory paragraph, because papers so often mess this up, and there should be a movement towards nailing it every time. There's plenty to like about this introductory paragraph. I like the focus on...

Yes. The NIH team's story is muddled. They have reported that there was no sign that the people with ME/CFS were fatiguing at a greater rate than the controls in the EFFrT study; tapping rate did not decline over the course of the study. The supposed (average) preference for easy tasks over...

There's some discussion about the use of stem cells here: USA, Texas - Long Covid stem cell trial - Hope Biosciences I note that Ren says that the clinic where he was treated with stem cells was rapidly closed down. Also, while he attributes some improvement to the treatment, he continued to...

Some discussion about stem cells here: USA, Texas - Long Covid stem cell trial - Hope Biosciences