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  1. Hutan

    Petition: S4ME 2023 - Cochrane: Withdraw the harmful 2019 Exercise therapy for CFS review

    We've had a burst of signatures from Switzerland - thanks so much to whoever is responsible for promoting the petition there for that.
  2. Hutan

    Larry Weed's 1971 Internal Medicine Grand Rounds - and quality management in health care generally

    Posting on behalf of @Louie41, this video covers a lot of the same ground as the Larry Weed presentation. (And that ground is important.) It's a nice listen although slow moving to start with. If you want to get to the guts of it, start at the 10 minute mark where the presenter, Dr Donald...
  3. Hutan

    Circulating miRNAs Expression in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2023 Soffritti et al

    There's this paper (not open access): miR-448 regulates potassium voltage-gated channel subfamily A member 4 (KCNA4) in ischemia and heart failure Results: The expression of KCNA4 is diminished in ischemia and human heart failure tissues with ventricular tachycardia. Previously, we have shown...
  4. Hutan

    £622,000 grant to improve diagnosis and treatment for ME/CFS and Long Covid

    I'm thankful, I really am. I think this project is good, and it's amazing that it's been awarded so much money. But who was consulted when they came up with the project name, LOCOME? Surely it would only take a little bit of thinking to realise that it is not a great name? Edit - Maybe it's...
  5. Hutan

    CAR-T therapy

    From the video (thanks for linking it Pibee) If I'm not mistaken, the plasmablasts actually head back into the bone marrow where they turn into plasma cells, including Long Lived Plasma Cells? Maybe we need something targeting CD138 cells? It does sound very interesting, an amazing technique.
  6. Hutan

    Long term sequelae following previous coronavirus epidemics O’Sullivan November 2020

    There's detailed information in this paper, but its conviction that physical rehabilitation is the way to go limits its use in advocacy.
  7. Hutan

    The risk of Long Covid developing from Covid-19 re-infections

    I'm wanting a good reference about the risk of Long Covid in subsequent infections. I couldn't find one immediately although I think we have seen a couple of papers on that topic. If I find them, I'll post them here. But if you put your finger on them immediately, please do let me know. Of...
  8. Hutan

    News from Africa

    A new paper out on PASC in Liberia: Prevalence and determinants of post-acute sequelae of COVID-19 in Liberia, 2023, Gwaikolo et al.
  9. Hutan

    Prolonged impacts of COVID-19-associated cystitis: A study on long-term consequences 2023 Wittenberg et al

    An alternative possibility to 'overactive bladder' which, from the abstract the authors don't consider, is that people with post-Covid ME/CFS may find that they are more prone to infections. I think a number of us with ME/CFS do find that we get flares of cold sores, or infections of various...
  10. Hutan

    Long Covid in the media and social media 2023

    Posts about a useful Canadian study on Long Covid epidemiology including rates with reinfections have been moved to the dedicated thread Experiences of Canadians with long-term symptoms following COVID-19, 2023, Kuang et al
  11. Hutan

    News from Canada

    Link to the thread on this useful report: Experiences of Canadians with long-term symptoms following COVID-19, 2023, Kuang et al
  12. Hutan

    Long Covid in the media and social media 2023

    Posts about a statement on Long Covid by the German Health Minister have been moved to News from Germany
  13. Hutan

    Deriving and validating a risk prediction model for long COVID, 2023, Jeffrey et al

    It's an interesting study. 1.1 million adults with Covid-19. 1 in 16 had Long Covid - 6.2%. That sounds reasonable, not the ridiculous percentages (e.g. 50%) that we have seen reported from some studies. I don't know how they defined Long Covid. However some of those risk factors (i.e. of...
  14. Hutan

    Long Covid in the media and social media 2023

    Posts about a Scottish study on risk factors for Long Covid have been moved to a new thread: Deriving and validating a risk prediction model for long COVID, 2023, Jeffrey et al
  15. Hutan

    Mirror: Tory minister demands comedian Ricky Gervais apologises for branding ME sufferers 'lazy' in offensive joke

    Well, that was the point I made upthread, yes, he very much does. The yoga teacher character's view, very much a BPS view, was displayed and criticised.
  16. Hutan

    Mirror: Tory minister demands comedian Ricky Gervais apologises for branding ME sufferers 'lazy' in offensive joke

    For what it's worth, I see those quotes differently, but then, I am a fan of flippancy. From watching some of Gervais' tv shows, it is clear that he isn't a stupid man. I don't think he is an uncaring one either. I think his humour tends to put bad behaviour on display, so we can laugh at the...
  17. Hutan

    Preprint Did “long COVID” increase road deaths in the U.S.?, 2023, Robertson

    I didn't read the whole paper. I took 'changes in accumulated COVID-19 cases' to mean current month cases - but I guess that doesn't really make sense - they could have just said 'current month cases' if that is what they meant. Perhaps 'cases in the previous month' means the most recent...
  18. Hutan

    Post-exertional malaise in daily life and experimental exercise models in patients with [ME/CFS], 2023, Vøllestad and Mengshoel

    Yes, but that study was self-reported symptoms. And we all know that GET proponents and the people who believe them only consider reports of improvements to be worth listening to, not reports of harm. And, honestly, even I have some doubts about the accuracy of the reports in terms of them...
  19. Hutan

    Post-exertional malaise in daily life and experimental exercise models in patients with [ME/CFS], 2023, Vøllestad and Mengshoel

    I know we've had that discussion before. But many people with ME/CFS push themselves to do activities that are as exhausting and risky as a CPET in order to achieve something they think is worthwhile. Fluge and Mella found participants for the cyclophosphamide trial. I think a multiple CPET...
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