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Hmm. I got a lactic acid monitor a while back and tested how much lactic acid was in my blood, before and after exercise. It was all normal; the increase in lactic acid cleared in a normal time. My breathing rate is normal. 'Fixing chronic hyperventilation syndrome' doesn't sound like the...

I attended this zoom meeting today. There was a group of just over 20 people with a welcoming and relaxed atmosphere. All except me were based in the US. The topic for this meeting was the recent IACFS/ME Conference - talking about presentations that were thought interesting. Probably, it...

Something to consider is that not all of the participants were included in each sub-study. So, for the muscle testing in vivo, there were only 15 people with ME/CFS. For the muscle biopsy, it varied according to the different tests done, but were only between 7 to 12 people with ME/CFS.

(I worked on this this morning, before running out of energy. I agree with Snow Leopard about the fatiguability study - it looked as though there was or soon would have been a significant difference.) The authors have covered a lot in this paper. Good to see that they are referring to ME/CFS...

Sure, but why would an experienced ME/CFS researcher who understands the consequences of the various criteria use a potentially mixed cohort? Some of the Fukuda sample may not have PEM.

Does the NIH ME/CFS study include muscle biopsies? I reckon there are probably lots of biopsies that could be gathered up from gastroscopies and colonoscopies done in people with ME/CFS.

@Snow Leopard's good comments notwithstanding, I think this is an interesting study done by the Dunedin team who operate with very little funding, most of it coming from donations from people with ME/CFS and their families. It will be good when authors of biology papers about ME/CFS don't feel...

In reply to @Yessica 's query elsewhere: The HealthPathways material is owned by HealthPathways and can normally only be accessed by medical professionals. It's not ideal as far as transparency goes, but it's the system we are working in. Also, even if I was allowed to, it's quite hard to share...

Thanks Yessica. I'll post about it over on the S4ME thread about HealthPathways.