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  1. M

    Gammaherpesvirus infection drives age-associated B cells toward pathogenicity in EAE and MS (2022) Mouat et al.

    Abstract While age-associated B cells (ABCs) are known to expand and persist following viral infection and during autoimmunity, their interactions are yet to be studied together in these contexts. Here, we directly compared CD11c+T-bet+ ABCs using models of Epstein-Barr virus (EBV)...
  2. M

    Covid-19 vaccination experiences

    Do they vaccinate everyone this time around? Here in Canada the new booster is offered to people 60 and over.
  3. M

    News from Canada

    No Simon Decary is a PhD in physiotherapy from Quebec and he is well versed in the ME issue. He is an ally.
  4. M

    Research news from Bhupesh Prusty

    It would create the appearance of a conflict of interest?
  5. M

    electric heat 'things' recommendations

    My heating pad is so helpful and soothing, but I have a hard time describing why. I use one as described by @hellytheelephant. The larger the better. I use it all year round, with the fan on and when it’s summer, with the AC on.
  6. M

    Protocol Faecal microbiota transplantation (FMT) in Norwegian outpatients with mild to severe ME/CFS: protocol (...), 2024, Skjevling et al. Comeback Study

    I know of someone who got a FMT and that landed them in ICU with sepsis, so I am concerned about this trial.
  7. M

    The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in ME/CFS ? 2023, Fernandez-Quiros et al

    I have done several of these computer-based, science calibre neuro-cognitive tests. They can be challenging and cause PEM. I developed a tactic over time, to get through them with the least amount of pain. Of course, knowing what test is being administered helps (say, remembering playing cards...
  8. M

    The Conners Continuous Performance Test CPT3™: Is it a reliable marker to predict neurocognitive dysfunction in ME/CFS ? 2023, Fernandez-Quiros et al

    I feel so sorry for the Barcelona patients who are being referred to a ‘central sensitization service’. It sounds like they are doomed from the get go.
  9. M

    A patient who recovered from post-COVID myalgic encephalomyelitis/chronic fatigue syndrome: a case report, 2023, Oka

    Axilla temperature is the least reliable measurement of them all. It is typically only performed on newborns.
  10. M

    EUROPEAN ME NETWORK (EUROMENE) Expert Consensus on the Diagnosis, Service Provision and Care of People with ME/CFS in Europe, 2020, Nacul et al.

    Many of us do this (rest/activity balance) intuitively, by necessity. In general we know our limits, we know when we go beyond our capacities and we know when we have gone too far. It is hard to fathom that in 2023 we are still here, reading scientific papers about activity management, CBT being...
  11. M

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    I agree we are such in a mess now because patients who have heard about the miraculous recoveries have asked for the same kind of assessment, and convinced practitioners to look into it, without much supporting evidence. This means that for at least some practitioners, there has been the lure of...
  12. M

    Editorial: Infectious and inflammatory mechanistic underpinnings of CFS/ME (2023) Burton

    There is no abstract but it is open access and quick read. Here is an excerpt: (Bolding is me adding explanation for the abbreviation)
  13. M

    Closed UK: DecodeME updates, was recruitment thread.

    People from out of country would be more than happy to submit to questionnaires and provide samples.
  14. M

    The Link Between Empty Sella Syndrome, Fibromyalgia, and CFS: The Role of Increased Cerebrospinal Fluid Pressure (2023) Hulens et al.

    Literature review papers represent the initial work to form a hypothesis, and indeed apply for funding to test it. It is also an opportunity for collaborators to work together and perhaps even include students (undergrad, masters and PhD), as it is them that do the brunt of the tedious work.
  15. M

    Digestion issue causing overexertion and severe weight loss

    Hello @cassava7, I am so very sorry you are dealing with this huge problem and have not found relief or even cause so far. I hope you can find answers in the tests that you are undergoing. I am not claiming to have answers for you, and you may already have explored these avenues, but I wonder...
  16. M

    The Link Between Empty Sella Syndrome, Fibromyalgia, and CFS: The Role of Increased Cerebrospinal Fluid Pressure (2023) Hulens et al.

    Full title: The Link Between Empty Sella Syndrome, Fibromyalgia, and Chronic Fatigue Syndrome: The Role of Increased Cerebrospinal Fluid Pressure Abstract: The etiopathogenesis of fibromyalgia (FM) and chronic fatigue syndrome (CFS) is not yet elucidated...
  17. M

    Altered Fatty Acid Oxidation in Lymphocyte Populations of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2023, Maya et al

    It's definitely labor intensive work. I believe this work was presented at IACFSME last summer, but I may be wrong. The main author presented something, I remember that.
  18. M

    Explanations for functional somatic symptoms across European treatment settings: A mixed methods study 2023 Saunders, Burton et al

    Right. The kind of collaborative relationship where the patient must accept and commit (aka ACT), must subscribe to their views of psychosomatic belief and must engage in active educative therapies to truly "believe".
  19. M

    Explanations for functional somatic symptoms across European treatment settings: A mixed methods study 2023 Saunders, Burton et al

    I would be curious to know whether the CFS services in the UK resemble these models? What is exactly happening? Also curious to know what happens in other countries.
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