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Abstract Objective The aim of this study was to compare the measure of grip strength against other validated methods of measuring frailty. Materials and methods This was a single-center, cross-sectional study that took place at the Westchester Medical Center Pre-Procedural Testing Clinic. The...

Introduction: Mutations and misfolding of membrane proteins are associated with various disorders, hence they make suitable targets in proteomic studies. However, extraction of membrane proteins is challenging due to their low abundance, stability, and susceptibility to protease degradation...

Abstract Most COVID-19 patients recovered with low mortality; however, some patients experienced long-term symptoms described as “long-COVID” or “Post-COVID syndrome” (PCS). Patients may have persisting symptoms for weeks after acute SARS-CoV-2 infection, including dyspnea, fatigue, myalgia...

Sadly, yes. But if we, at least, don't point that out there is little counterpoint to the almost inevitable hype.

"ME/CFS patients with high HHV-6 load have a more severe course of the disease, thus confirming that the severity of the disease depends on the viral load—the course of the disease is more severe with a higher viral load." Or the immune system of someone who is less well will find it harder to...

News in Brief for w/c 3rd Oct https://www.facebook.com/sci4me/posts/pfbid02LFhfR18tQeS8qhkYBkvJjjuvu855xYMFy3AwDqz3QjfTf2kVeUAYrNLvdD7djRRCl Research papers thread https://www.facebook.com/sci4me/posts/pfbid02kYwygzbaFHw7CKALTsbEkXsGWYoKZsTx9jed4sWNNA5aXjSNfp55k7qtcECSwJJKl

Social media moves more quickly than established systems for formal trials? Of course it does, that should be no surprise to anybody. And what should not surprise anybody is that a quick Twitter poll, which will be open to all kinds of bias, on the efficacy of an alleged treatment should not be...

Then you will be delighted to know that DecodeME (sign up to the study at www.decodeme.org.uk) includes a question about course of illness in which an option is available to indicate progressive deterioration.

Who has been rattling his cage? "NICE guidance on ME/CFS is the most extraordinary corruption of the evidence-based guidelines process I have ever seen. See this article in the Lancet" https://twitter.com/PaulGarnerWoof/status/1579099446448885760

$13,074 raised, 22 days left. https://crowdfund.berkeley.edu/project/33528

Abstract The SARS-CoV-2 pandemic has added new urgency to the study of viral mechanisms of infection. But while vaccines offer a measure of protection against this specific outbreak, a new era of pandemics has been predicted. In addition to this, COVID-19 has drawn attention to post-viral...

Abstract The Coronavirus Disease 2019 (Covid-19) pandemic has profoundly affected the quality of life (QoL) and health of the general population globally over the past 2 years, with a clear impact on people with Parkinson's Disease (PwP, PD). Non-motor symptoms have been widely acknowledged to...

Abstract The Coronavirus Disease 2019 (Covid-19), caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has led to unprecedented challenges for the delivery of healthcare and has had a clear impact on people with chronic neurological conditions such as Parkinson's disease...

Full title: Sleep symptoms are essential features of long-COVID – Comparing healthy controls with COVID-19 cases of different severity in the international COVID sleep study (ICOSS-II) Summary Many people report suffering from post-acute sequelae of COVID-19 or “long-COVID”, but there are...

I'm sure they won't be..... Esther Crawley gets 'commendation' at 2017 Maddox Prize awards.

Manages not to mention ME even once. It does end with "This study advances clinical understanding of PASC symptoms and their impact on human life. Because nurses are experts in symptom management and there is no cure or treatment for PASC, nurse clinicians and researchers play a critical role...

Abstract Aims and Objectives To determine the frequency, timing, and duration of post-acute sequelae of SARS-CoV-2 infection (PASC) and their impact on health and function. Background Post-acute sequelae of SARS-CoV-2 infection is an emerging major public health problem that is poorly...

Full title: The GoodHope Exercise and Rehabilitation (GEAR) Program for People With Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders Introduction: The Ehlers-Danlos Syndromes (EDS) and Generalized Hypermobility Spectrum Disorders (G-HSD) comprise a heterogeneous group of...

Abstract Metabolic disorders or inborn errors of metabolism (IEMs) can have a wide range of neurodevelopmental and behavioral presentations. These can vary with age and/or management or stressors from common childhood/intercurrent illnesses/procedures/interventions. Collaborative care models...