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Abstract Exercise limitation in COVID-19 survivors is poorly explained. In this retrospective study, cardiopulmonary exercise testing (CPET) was coupled with an oxidative stress assessment in COVID-19 critically ill survivors (ICU group). Thirty-one patients were included in this group. At...

Abstract Background: Despite significant improvements in COVID-19 therapy, many patients still present with persistent symptoms and quality-of-life alterations. The aim of this study was to simultaneously investigate the long-term evolution of autonomy, malnutrition and long-lasting symptoms in...

Abstract COVID-19 is not only a short-term infection, as patients (pts) recovering from SARS-CoV-2 infection complain of persisting symptoms, which may lead to chronic fatigue syndrome. There is currently no evidence that nutritional supplements can assist in the recovery of pts with chronic...

[UK] 110,000 workers missing from work as a result of long COVID at a cost of £1.5 billion a year in lost earnings "The number of people with long COVID (defined as reporting symptoms more than four weeks after infection) has been on the rise – with the latest ONS figures showing that there...

My cruel teacher – Long Covid | Nisreen Alwan | TEDxSouthamptonUniversity

Update from the MEA on their communications with various parts of the NHS about the new guideline. "This is a brief update on what has happened to far East Kent NHS Trust: Information leaflet on physiotherapy for ME/CFS withdrawn within hours...

Trial By Error: Professor Chalder Reports CBT Does Not Work for Post-Stroke Fatigue, Calls for More Research https://www.virology.ws/2022/07/26/trial-by-error-professor-chalder-reports-cbt-does-not-work-for-post-stroke-fatigue-calls-for-more-research/

Abstract Background Lyme disease is a tick-borne illness that causes an estimated 476,000 infections annually in the United States. New diagnostic tests are urgently needed, as existing antibody-based assays lack sufficient sensitivity and specificity. Methods Here we perform transcriptome...

Full title: Serological Analysis Identifies Consequential B Cell Epitopes on the Flexible Linker and C-Terminus of Decorin Binding Protein A (DbpA) from Borrelia burgdorferi ABSTRACT Decorin binding protein A (DbpA) is a surface adhesin of Borrelia burgdorferi, the causative agent of Lyme...

Adam Lowe, known in some incarnations as Beyonce Holes, is a longtime ME/CFS patient and advocate in Manchester, England, served as a lay member of the committee that produced the new clinical guidance published last October by the UK’s National Institute for Health and Care Excellence. (This...

Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 condition or long COVID. We undertook a retrospective matched cohort study using a UK-based primary care...

Abstract Our body has a remarkable ability to remember its past encounters with allergens, pathogens, wounds and irritants, and to react more quickly to the next experience. This accentuated sensitivity also helps us to cope with new threats. Despite maintaining a state of readiness and...

Introduction There is growing interest in the relationship between fibromyalgia and processes related to food, such as food intolerances. In fact, different associations have been described between the control of dietary habits and the improvement of the different symptoms of fibromyalgia...

Abstract The modified 2-tier testing algorithm (MTTT) for Lyme disease (LD) has been approved by the US Food and Drug Administration. In this study, we show that the MTTT detected 28% more cases of early infection compared with the standard 2-tier algorithm while retaining high specificity in a...

Highlights • Neuropsychiatric symptoms are often reported following COVID-19 infection. • Self-reported symptoms may not be associated with objective dysfunction. • Self-reported symptoms may be associated with depression and anxiety. • Cognitive testing may overestimate clinical impairment in...

Full title: Persistent dyspnea after COVID-19 is not related to cardiopulmonary impairment; a cross-sectional study of persistently dyspneic COVID-19, non-dyspneic COVID-19 and controls Background: Up to 53% of individuals who had mild COVID-19 experience symptoms for >3-month following...

Multisystem inflammatory syndrome in children (MIS-C) is a febrile pediatric inflammatory disease that may develop weeks after initial SARS-CoV-2 infection or exposure. MIS-C involves systemic hyperinflammation and multiorgan involvement, including severe cardiovascular, gastrointestinal (GI)...

Abstract Background Prolonged recovery is common after SARs-CoV-2 infection, however the pathophysiological mechanisms underpinning Long COVID syndrome remain unknown. VWF-ADAMTS13 imbalance, dysregulated angiogenesis and immuno-thrombosis are hallmarks of acute COVID-19. We hypothesized that...

Full title: Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study Summary Background Post-COVID syndrome (PCS) is an important sequela of COVID-19, characterised by symptom persistence for >3 months...