As Wonko points out, there are some who claim to have an animal model already, but it is simply rodents exercised to exhaustion, so hardly a useful one.
Frankly, I would need to see the details before getting behind the idea of experimentation on animals for ME research. One person's "good...
ABSTRACT
Background:
Between 30-76% of COVID-19 patients have persistent physical, cognitive and/or mental symptoms, sometimes up to 9 months after acute COVID-19 infection. The expected rush of patients needing rehabilitation put pressure on primary care practices and resources, particularly...
ABSTRACT
Introduction
Fibromyalgia involves chronic pain and disrupted physical activity and sleep. Research examining the relationship between pre-bedtime physical activity, pain, and objective sleep is limited. This study examined whether objectively measured physical activity levels (via...
Abstract
Background
Symptoms of functional neurological disorder tend to be variable, yet patients often report them being present constantly and of permanently severe intensity. Furthermore, they typically worsen when they are mentioned or during clinical examination. Such phenomena are...
Abstract
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in prolonged pathologies collectively referred to as post-acute sequalae of COVID-19 (PASC) or long COVID. To better understand the mechanism underlying long COVID biology, we...
"Rehabilitation based on medical needs using a multi-disciplinary approach, freed from counterproductive administrative and financial hurdles, with sufficient support for those with little or no access to informal care."
https://longcovideurope.org/
Eggs can survive decades without signs of aging. Now, scientists may know why
"Mitochondria power the cell by taking electrons and using them to make a cellular fuel called ATP, through a process known as oxidative phosphorylation. It doesn’t happen all at once, but in a series of linked steps...
Abstract
Oocytes form before birth and remain viable for several decades before fertilization1. Although poor oocyte quality accounts for most female fertility problems, little is known about how oocytes maintain cellular fitness, or why their quality eventually declines with age2. Reactive...
Trial By Error: Mom Speaks Out About NHS “Abuse” of Daughter; Norway Approves Lightning Process Study
"I have written frequently about the Lightning Process, most recently about a proposed clinical trial in Norway. On July 13th, NEM, the Norwegian research ethics authority, announced that it...
Trial By Error: Mom Speaks Out About NHS “Abuse” of Daughter; Norway Approves Lightning Process Study
"On Monday, The Times (UK) published a story about a 17-year-old girl with ME who has experienced hospital treatment that her family has referred to as “neglect and abuse.” The details are...
"An important structural issue of relevance to the above discussion is the historical tendency in healthcare settings, notably in the UK, to recommend cognitive behavioural therapy (CBT) and/or graded exercise therapy (GET) for particular conditions that have been positioned as ‘medically...
Abstract
While critically informed approaches to medical education are increasingly advocated in literature, discussion of the potential role of disability studies in informing pedagogy and practice is largely lacking. The emergence of long Covid, alongside the strong possibility of a wave of...
Full title: Physical and psychological reconditioning in long COVID syndrome: Results of an out-of-hospital exercise and psychological - based rehabilitation program
Abstract
Background
Long Covid Syndrome (LCS) is used to describe signs and symptoms that continue or develop after acute...
Now published.
Abstract
Introduction
There is limited literature on cardiovascular manifestations of post-acute sequelae of SARS-CoV-2 infection (PASC).
Methods
This observational study aimed to describe the characteristics, diagnostic evaluations, and new cardiac diagnoses in patients...
Abstract
Aim
We aimed to describe the long-term outcome with respect to symptom persistence amongst children hospitalised for COVID-19.
Methods
This was a follow-up study of 58 children and adolescents hospitalised with COVID-19. For all patients, the data were collected in a phone call to the...
Abstract
Background
Acute Coronavirus Disease 2019 (COVID-19) has been associated with new-onset cardiovascular disease (CVD) and diabetes mellitus (DM), but it is not known whether COVID-19 has long-term impacts on cardiometabolic outcomes. This study aimed to determine whether the incidence...
"Primary outcome variable
Neuroticism was self-rated on an abridged version of The Eysenck Personality Questionnaire (EPQ-N) with six items concerning long-term personality characteristics17. Each item was rated as present (1) or absent (0). The sum score ranged from zero to six, and higher...
Abstract
Neuroticism is a basic personality trait concerning negative feelings under stressful conditions. Our purpose was to examine the rate of high neuroticism and factors associated with high neuroticism in long-term (≥ 5 years) survivors of childhood, adolescent, and young adult cancer...
Key Points
Convex membrane curvature and phosphatidylserine create discreet binding locations for lactadherin and coagulation factor V(a)
Stressed endothelial cells extend filaments with both high convexity and PS, establishing discreet sites of prothrombinase activity
Prior reports...
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