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Abstract Objective People with functional somatic symptoms have difficulties in various stages of the emotion regulation (ER) process (1). As an adaptive and flexible use of ER strategies is a core tenet of emotional health, having difficulties in this area is often assumed to be the key...

Abstract Chikungunya fever is an arboviral illness caused by chikungunya virus (CHIKV) and transmitted by the bite of Aedes aegypti and Aedes albopictus. It is an RNA virus belonging to the genus Alphavirus and family Togaviridae. We present a case series of three patients with chikungunya...

Highlights scATAC-seq and scRNA-seq reveal expansion of an MBC subset in chronic LCMV infection A distinct chronic MBC subset is associated with increased IFN-I-associated ISG signature The chromatin landscape of MBCs is established during a critical window early in infection IFN-I dynamics...

"Perceived misdiagnoses When entering the register, participants were asked if they had received any additional psychiatric diagnoses in the past, before receiving a diagnosis of autism (“Have you received any other (psychiatric) diagnose(s) in the past before receiving your diagnosis within...

Summary Background Many autistic people, particularly women, do not receive an autism diagnosis until adulthood, delaying their access to timely support and clinical care. One possible explanation is that autistic traits may initially be misinterpreted as symptoms of other psychiatric...

Current total is 10,626 https://www.change.org/p/cochrane-withdraw-the-harmful-2019-exercise-therapy-for-cfs-review

"we wish to ... identify the barriers that are holding us back from realising the full value of patient and public partnership in healthcare" Such as only giving 21 days notice of a deadline for proposals?

"A special issue To mark 10 years of commitment to patient partnership and over 20 years since our first patient theme issue, we will publish a special issue of The BMJ led by patients on 13 July 2024. We expect that most of the content will be written by patients or led by their views...

ABSTRACT Introduction Functional neurological disorder (FND) is a neuropsychiatric disorder that manifests in a broad array of functional motor, sensory, or cognitive symptoms, which arise from complex interactions between brain, mind, body, and context. Children with FND make up 10%–20% of...

@dave30th , an 'interesting' one for you.

Introduction The classification of the so-called “functional” psychiatric disorders has long been debated. Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV; 1994) retained the “somatoform” psychological-primacy concept but had poorly devised subdivisions with...

Published papers thread for w/c 1st April. Facebook: https://www.facebook.com/sci4me/posts/pfbid0acxNpGXucCKKiGXnvnJQW3pacwHbBXxV9uPZ14sMunrNpHQMYgfsA4bqz8hLkVdTl Mastodon: https://med-mastodon.com/@s4me/112234932500952686

Abstract Nattokinase, from the Japanese fermented food natto, is a protease with fibrinolytic activity that can thus degrade conventional blood clots. In some cases, however, including in Long COVID, fibrinogen can polymerise into an anomalous amyloid form to create clots that are resistant to...

Trial By Error: My Letter to Scientific Reports about New Study of Physical Activity and Long Covid "The other day I posted a blog about yet another problematic Long Covid study published by a major journal. The study concluded that physical activity (PA) can “reduce” symptoms in young women...

'‘Health and Well-being’ self-care support sessions aim to support self-management of common symptoms and risk factors and to enhance self-management skills, including problem-solving, planning, self-monitoring and cognitive adaptation. The list of core sessions that will be delivered to...

Abstract Introduction Personalised Exercise-Rehabilitation FOR people with Multiple long-term conditions (PERFORM) is a research programme that seeks to develop and evaluate a comprehensive exercise-based rehabilitation intervention designed for people with multimorbidity, the presence of...

News in Brief posts for w/c 1st April. Facebook: https://www.facebook.com/sci4me/posts/pfbid023oqeG7sYeyP5auijB3gZo9b3HmA49zZ6X2TE5mQhAJGnxG8LyTXCGvV7t4ia23ZEl Mastodon: https://med-mastodon.com/@s4me/112229108518479720

Abstract Ehlers–Danlos syndromes (EDS) are a group of connective tissue disorders caused by mutations in collagen and collagen-interacting genes. We delineate a novel form of EDS with vascular features through clinical and histopathological phenotyping and genetic studies of a three-generation...

"The Bill & Melinda Gates Foundation, one of the world’s top biomedical research funders, will from next year require grant holders to make their research publicly available as preprints, articles that haven’t yet been accepted by a journal or gone through peer review. The foundation also said...

Yet it probably won't. The FND researchers will just point at this sort of research, proclaiming 'See, FND is actually a thing, these results prove it!', despite years of advocating for the smallest amount of investigation that can be got away with.