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  1. Jonathan Edwards

    I need a good summary of the problems with mind-body theory

    I cannot think of any specific documents. It is such a huge question. But the simple answer is that it is just a theory - based on popular myths given scientific sounding names. We have no means of testing the idea that the mind influences the body beyond what is obvious - we walk to the fridge...
  2. Jonathan Edwards

    Investigating Fatigue and Exercise Intolerance in a University Immunology Clinic, 2020, Ambrus et al

    I have only read the abstract but I don't think this should be taken seriously. I have never heard of the journal which looks like a garbage bag online outfit (the blurb reads as if written by someone who knows nothing about medicine) The figures claimed for glycogen storage make no sense since...
  3. Jonathan Edwards

    News from Canada

    That does not sound like confusing CFS with fatigue? Fatigue is being used as one of many symptoms Covid-19, amongst many. That would be similar to chronic fatigue syndrome where fatigue is one of many symptoms?
  4. Jonathan Edwards

    United Kingdom: ME Association governance issues

    I think part of the problem is that MEA have for some time bought in to the idea of having a range of treatments rather than one size fits all and having services delivered by multidisciplinary teams. I have no real idea why they go for this other than that there is a widespread meme about that...
  5. Jonathan Edwards

    United Kingdom: ME Association governance issues

    That would be my impression judging by the transcript of the interview. PWME need advocates who understand the level of ignorance within the medical profession, not those who profess to know the answer.
  6. Jonathan Edwards

    Functional neurological disorder: lighting the way to a new paradigm for medicine, 2021, Edwards

    Indeed. how do we deal with the problem that, as currently constituted, these methods are not easily applicable to understanding the complex interface between biology and environment that occurs within humans who are ill, and therefore to studying the process of rehabilitation? You get on and...
  7. Jonathan Edwards

    Functional neurological disorder: lighting the way to a new paradigm for medicine, 2021, Edwards

    Not LW, although he got so cynical about philosophy that it is hard to know if he believed anything at the end. Cartesian Dualism is of course itself a category error, because, as understood by the people who own the term, it bears little relation to the thinking of Rene Descartes. I would...
  8. Jonathan Edwards

    Indeterminate pain

    I think I can get some idea of what you are experiencing, having had intangible experiences of this sort myself, if not quite this. I don't think there is a logical inconsistency. Sensations that seem to be of a certain type, devoid of any specifics to make them a case that type are not that...
  9. Jonathan Edwards

    Will it ever be reasonably safe for PwME to go back into society, post-Covid?

    I am more confident than I was. The case numbers are still much the same and deaths are falling slightly. Countries that had a recent wave earlier than us are seeing numbers drop right off. I think the current wave will be the last and will Peter out some time at the end of the year.
  10. Jonathan Edwards

    Effect of Pain Reprocessing Therapy vs Placebo and Usual Care for Patients With Chronic Back Pain an RCT, 2021, Asher, Gordon et al

    I doubt anybody does much. The prefrontal region is where higher thoughts and thoughts about self tend to be. So reduced activity in prefrontal region might indicate not thinking such complicated thoughts about how the pain was for oneself. Or it might indicate less in the way of thought about...
  11. Jonathan Edwards

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    I am struggling to see how they hope to publish a paper on two patients?
  12. Jonathan Edwards

    Evidence-based psychological interventions for adults with chronic pain: precision, control, quality, and equipoise, 2021, Williams, Eccleston et al.

    Silly me, someone is marketing CBT of course, but why would Cochrane employ a marketing executive who believes in 'pushing' treatments? You can't make it up.
  13. Jonathan Edwards

    Evidence-based psychological interventions for adults with chronic pain: precision, control, quality, and equipoise, 2021, Williams, Eccleston et al.

    What on earth is that picture about? Is somebody selling degrees in business studies at Bridlington Virtual University?
  14. Jonathan Edwards

    Cochrane Method Group: Stakeholder Engagement in Guideline Development / MuSE Consortium

    There seems to me to be something badly wrong with this whole idea. What you want to do to optimise a guideline is to make sure you get information from all groups of people who may have important information about what the reliable evidence really is on what matters to patients and what can...
  15. Jonathan Edwards

    Reducing bias in trials from reactions to measurement: the MERIT study including developmental work and expert workshop, 2021, French et al

    I suspect that they have not considered how much attempting to measure how much measuring things in trials affects measurements is likely to affect the measurements of how much measuring things affects measurements. They might need to set up a-committee to measure this.
  16. Jonathan Edwards

    Article Independent IE: Doctors urged to look out for chronic fatigue syndrome in long Covid patients (#Physios4ME)

    That sounds like quasi-physiological theorising to me. I am not sure what a positive effect on the autonomic nervous system would be. I don't want to sound picky all the time but it would be good to sweep the cupboard clean when it comes to such theorising and move on to a genuinely...
  17. Jonathan Edwards

    (Daily Telegraph) “How I became a target for the ME militants” by Dr Michael Fitzpatrick

    And of course those who build their persona and social identity out of accumulating contrarian beliefs are likely to expect everyone else to collect beliefs. The difference from their own case being that those beliefs will be wrong - since the holders do not belong to the enlightened elite.
  18. Jonathan Edwards

    (Daily Telegraph) “How I became a target for the ME militants” by Dr Michael Fitzpatrick

    As others have indicated there are many ways in which far left and far right converge - Orwell is full of it - but I think this is something unrelated. This is simply a group of people who have found solace in the idea that they belong to an elite of minds who are one step cleverer than...
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