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    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    It would be interesting to see how informed consent was for this trial. Given what is known about interferon , what risks were explained to participants? Were they all aware that potentially there was a ?% chance that they would not recover?
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    Genome-epigenome interactions associated with ME/CFS, 2018, McGowan et al.

    I have not read the paper, so this may be drivel. To me it is not one thing, one expression that we should be lookong for in a systems condition. It is combinations which may be expressed more significantky in ME/ CFS. It is a systems condition and expression will be modulated by original...
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    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    Changing which format of the chalder fatigue scale you use to try and achieve a reportable p- number?
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    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    Not to mention contacting GPs who have done their CPD webinars and letting them know that the info is not pukka.
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    Dr Karl Morten - UK researcher based at Oxford University

    Thank you Norman Booth. He pestered and pestered re mitochondrial research until someone was interested. Great that it is Karl Morton
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    NICE guideline review: A list of appointees to the ME/CFS Guideline Committee has now been published

    Thank you for this reassurance. However i have a feeling that the deckchairs are currently being nailed down. There seems to be a subtle realignment underway, for which the treatment may well be CBT. I hope that i am wrong.
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    NICE guideline review: A list of appointees to the ME/CFS Guideline Committee has now been published

    "Scientifically robust" seems like an oxymoron in this context.
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    B12/Folic Acid and D3/K2 Supplementation

    I' m tagging @JaimeS as i believe that she has had issues with B12. My aunt cannot take B12 she has had a horrendous reaction on both occasions that she tried. I don' t know which version she took - methylated versions may be an issue for some people. This is unusual as most of the literature...
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    Severe posterior hypometabolism but normal perfusion in a patient with CFS/ME revealed by PET/MRI, 2018, Sahbai et al.

    So this could be helpful for a number of teenage girls who developed "CFS" following Gardisil injections ?
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    Persistent fatigue induced by interferon-alpha: A novel, inflammation-based, proxy model of Chronic Fatigue Syndrome, 2018, Pariante et al

    Step 1 - define area of interest Step 2 - conduct a literature review to enable you to either build on previous findings/ explore a " gap" in knowledge From undergraduate stats lectures- first lecture. I take it the literature review was as all encompassing as the above result would suggest...
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    Physical Activity and Sleep in CFS and Fibromyalgia Syndrome: Associations with Symptom Severity in the General Population Cohort, 2018, Joustra et al

    Are actometers worn all the time? From a previous thread relative to paediatric EC studies i seem to remember that their use was intermittent ( could be wrong) . In which case what is being measured is a key question. The link to activity and misdiagnosis is interesting and may be another...
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    A predictive algorithm to identify genes that discriminate individuals with fibromyalgia syndrome diagnosis from healthy controls, 2018, Saliqan et al

    I agree, but virtually impossible to get anyone to consider this. I' ve given up with my GP and no private providers do any other investigative processes anywhere near us. I am hoping that this gets further study.
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    Cochrane Exercise Review Withdrawn - Individual Patient Data

    A couple of queries Is this the proposed study whose reviewers savaged it and was likely never to be published? Is this a means of not providing data that can be analysed by others ?
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    Livestream Alan Light, PhD today at 6pm MST "New findings suggest that multiple mitochondrial mutations create susceptibility for ME/CFS"

    Similar to @BeautifulDay ' s theory that some genetic mutations create a predisposition . Link to PR thread where there are some slides https://forums.phoenixrising.me/index.php?threads/video-mutations-in-energy-and-autoimmune-genes-cooperate-to-cause-me-cfs-with-alan-light-phd.62439/#post-1016900
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