It would be interesting to see how informed consent was for this trial.
Given what is known about interferon , what risks were explained to participants?
Were they all aware that potentially there was a ?% chance that they would not recover?
I have not read the paper, so this may be drivel. To me it is not one thing, one expression that we should be lookong for in a systems condition. It is combinations which may be expressed more significantky in ME/ CFS.
It is a systems condition and expression will be modulated by original...
Thank you for this reassurance. However i have a feeling that the deckchairs are currently being nailed down.
There seems to be a subtle realignment underway, for which the treatment may well be CBT.
I hope that i am wrong.
I' m tagging @JaimeS as i believe that she has had issues with B12.
My aunt cannot take B12 she has had a horrendous reaction on both occasions that she tried. I don' t know which version she took - methylated versions may be an issue for some people.
This is unusual as most of the literature...
Step 1 - define area of interest
Step 2 - conduct a literature review to enable you to either build on previous findings/ explore a " gap" in knowledge
From undergraduate stats lectures- first lecture. I take it the literature review was as all encompassing as the above result would suggest...
Are actometers worn all the time? From a previous thread relative to paediatric EC studies i seem to remember that their use was intermittent ( could be wrong) . In which case what is being measured is a key question.
The link to activity and misdiagnosis is interesting and may be another...
I agree, but virtually impossible to get anyone to consider this. I' ve given up with my GP and no private providers do any other investigative processes anywhere near us. I am hoping that this gets further study.
A couple of queries
Is this the proposed study whose reviewers savaged it and was likely never to be published?
Is this a means of not providing data that can be analysed by others ?
Similar to @BeautifulDay ' s theory that some genetic mutations create a predisposition .
Link to PR thread where there are some slides
https://forums.phoenixrising.me/index.php?threads/video-mutations-in-energy-and-autoimmune-genes-cooperate-to-cause-me-cfs-with-alan-light-phd.62439/#post-1016900
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