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  1. J

    Aripiprazole - Abilify

    Aripiprazole as a Candidate Treatment of COVID-19 Identified Through Genomic Analysis https://www.frontiersin.org/articles/10.3389/fphar.2021.646701/full?fbclid=IwAR2lNXJE2z6w8TAJf33hf9qEGsgC3Ux09818WlDc8-p5K-UB7q6py4yf7qU Background: Antipsychotics modulate expression of inflammatory...
  2. J

    BPS attempts at psychologizing Long Covid

    Remind me to stay off the Twitter......
  3. J

    BPS attempts at psychologizing Long Covid

    Merged thread. 'The Search to Explain Our Anxiety and Depression: Will ‘Long COVID’ Become the Next Gender Ideology?' https://quillette.com/2021/04/15/the-search-to-explain-our-anxiety-and-depression-will-long-covid-become-the-next-gender-ideology/ Calls CFS a contested illness. Ugh.
  4. J

    No signs of neuroinflammation in women with [CFS] or Q fever fatigue syndrome using the TSPO ligand [11C]-PK11195, 2021, Raijmakers, Knoop et al

    5 tweet thread
  5. J

    Prevalence of (ME/CFS) in three regions of England: a repeated cross-sectional study in primary care, 2011, Lacerda,Nacul

    OK--but maybe you missed these two folks from the ALS list? David Niven (1910–1983), British actor.[82] Mao Zedong (1893–1976), Chinese statesman.[112]
  6. J

    Prevalence of (ME/CFS) in three regions of England: a repeated cross-sectional study in primary care, 2011, Lacerda,Nacul

    Is it possible that MECFS is much rarer than acknowledged? For example. Prevalence of ALS is 1 out 20,000 people or 0.005%--so MECFS has ~40X the prevalence of ALS. Now look at this anecdotal "stuff" https://en.wikipedia.org/wiki/List_of_people_with_amyotrophic_lateral_sclerosis...
  7. J

    Acupuncture therapy on chronic fatigue syndrome based on radar plot..., 2021, Tang et al

    Lot of work going on here for this important contribution! Author contributions Conceptualization: Lijie Tang, TaiJun Jang, Xi Wu. Data curation: Lijie Tang, Taijun Jiang, FengYa ZHu, ZHengKang Liu. Formal analysis: Lijie Tang, TaiJun Jang. Funding acquisition: Xi Wu. Investigation: Lijie...
  8. J

    Acupuncture therapy on chronic fatigue syndrome based on radar plot..., 2021, Tang et al

    Not even a study. An article about a useless review that they plan to undertake. So basically 2nd order uselessness. Important result!
  9. J

    Brain Fog Article The Atlantic—The way out of Brain Fog

    https://www.theatlantic.com/health/archive/2021/04/brain-fog-treatments/618568/ Not a helpful article IMO...yoga, meditation yada yada yada.
  10. J

    Encephalitis lethargica - The forgotten epidemic

    Are we sure that EL isn’t just severe ME/CFS? Why hasn’t there been an big outbreak of EL in recent years?
  11. J

    A pilot study of oxidative pathways in MS fatigue: randomized trial of N‐acetyl cysteine, Krysko, 2021

    Memantine similarly doesn’t do much for MS. https://www.frontiersin.org/articles/10.3389/fneur.2020.574748/full https://www.docwirenews.com/condition-center/multiple-sclerosis-knowledge-hub/memantine-does-not-improve-ms-fatigue/
  12. J

    A pilot study of oxidative pathways in MS fatigue: randomized trial of N‐acetyl cysteine, Krysko, 2021

    https://onlinelibrary.wiley.com/doi/10.1002/acn3.51325 Interpretation NAC was well‐tolerated in progressive MS, although reduction in fatigue on NAC was similar to placebo. Antioxidant blood and MRS biomarkers were not significantly altered by NAC, which could be due to dose, route of...
  13. J

    Once-Weekly Semaglutide in Adults with Overweight or Obesity, 2021, Wilding et al

    Looks like a new phase was reported at a conference. Seems like you will need to be on this for life...or else you gain the weight back. Blockbuster drug for Novo Nordisk. https://www.healio.com/news/endocrinology/20210323/step-4-significant-weight-loss-maintained-with-weekly-semaglutide site...
  14. J

    Skewing of the B cell receptor repertoire in myalgic encephalomyelitis/chronic fatigue syndrome, 2021, Sato et al

    Hopefully @Jonathan Edwards could comment on this study.
  15. J

    Reconciling estimates of global spread and infection fatality rates of COVID‐19: an overview of systematic evaluations, 2021, Ioannidis

    Yes....that guy
  16. J

    Reconciling estimates of global spread and infection fatality rates of COVID‐19: an overview of systematic evaluations, 2021, Ioannidis

    Good thread on this topic....
  17. J

    Reconciling estimates of global spread and infection fatality rates of COVID‐19: an overview of systematic evaluations, 2021, Ioannidis

    https://onlinelibrary.wiley.com/doi/10.1111/eci.13554 Abstract Background Estimates of community spread and infection fatality rate (IFR) of COVID‐19 have varied across studies. Efforts to synthesize the evidence reach seemingly discrepant conclusions. Methods Systematic evaluations of...
  18. J

    Reconciling estimates of global spread and infection fatality rates of COVID‐19: an overview of systematic evaluations, 2021, Ioannidis

    Mods have added a first post to provide the abstract and link and changed the thread title. Original thread title: Ioannidis ad-hominem attack paper Not MECFS, but indicative of the status of peer-reviewed journals. Or maybe none of the reviewers read the appendix.
  19. J

    Open Medicine Foundation (OMF)

    Over 20,000 FDA approved meds. Hopefully something would work.... https://www.fda.gov/about-fda/fda-basics/fact-sheet-fda-glance
  20. J

    Open Medicine Foundation (OMF)

    Thread from Ben H here
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