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I think we should acknowledge the researchers who are willing to put their names to this paper and the institutions that allow them to produce this rubbish: Christina M.van der Feltz-Cornelis Department of Health Sciences, Hull York Medical School, University of York, UK Marjan Bakker...

I found myself sitting with my mouth agape, appalled at this study. Close inspection of it did not help at all. Checking out Table 4 which presents a selection of the results - presumably the best they could muster from the vast cherry orchard that was this study: IL6 was related to age...

Yes, supplementary material. One thing they did do well was provide a lot of additional information.

The beliefs these researchers hold are really rather bizarre.

Recruitment So participants had already self-selected to believe that mind-body treatments could be useful.

The Study of the Therapeutic Encounter Foundation has a website that someone forgot to finish. Here's the 'about' tab: The Psychophysiologic Disorders Society is even more intriguing. This is what they say about this study: The 'amazing' result of the trial apparently drew the attention of...

And then there's the old 'obfuscate the followup measurements, by allowing the wait list participants to do the other treatments' trick. Here, half of the 'treatment as usual' patients were allowed to have the open-label saline injection placebo after the one month treatment period had ended...

Columns are: Pain Reprocessing Trmt: Placebo: Treatment as usual So, on average, the people with the brainwashing treatment were drinking more alcohol at the end of the treatment, while people in the other two arms were drinking less. They were using more opioid pills while the people in...

This is annoying on so many levels. I started out feeling dreadfully sorry for the rats, who were put through this for no good reason. I ended up also feeling dreadfully sorry for all the people with ME/CFS who are now going to have well-meaning relatives encouraging them to try this 'cure'.

All of the illnesses that can cause ME/CFS - EBV infection, Q-fever... have a long tail of people who have ME/CFS-like symptoms for months after the illness. Most get better, but most who reach the two year mark don't. At some point in that time, people who don't recover will probably get a...

(This is a version of a post I made on this thread earlier and deleted) This is great: But this is arguable, and, even if true, tends to bolster the idea of MUS rather than diminish it.: I think the paper falls into the trap of putting up poorly evidenced biological models to counter...

I don't think so. I had what was diagnosed as euthyroid Graves eye disease a lot of years ago, and so have had my thyroid function checked most years, and it has always been fine. It was last checked a few months ago. And the chills have been a feature of my experience of PEM throughout...

That's interesting @paused_me. How credible is the test? 'Intracellular electrical capacity - in lymphocytes' - how does that work? May I ask: Did a clinician order the test? How are they proposing to use the results?

When trying to find out how long ciprofloxacin might last in the body, I came across this paper: https://www.hindawi.com/journals/isrn/2012/374212/ Accumulation and Elimination of Enrofloxacin and Ciprofloxacin in Tissues of Shrimp Litopenaeus vannamei under Laboratory and Farm Conditions It...

Very sad to hear about that situation. @Andy, re Woolie's enquiry. A long shot, but perhaps your friend might recall the name of their psychiatrist/psychologist?

I'm sure the website will make a big difference. Hungary has a population of nearly 10 million people, so that is a lot of people with ME/CFS, and families of people with ME/CFS, and doctors who have patients with ME/CFS who now have curated resources in their own language that are easy to...

For the last few days, I've been ending up in bed in the afternoons, unable to get warm, exhausted and feeling chills. I guess it's PEM, although it seems to just last a few hours and doesn't involve the body crushed pain that is my experience of full-on PEM. Chills are a frequent feature of...

A member made a typo recently (or perhaps they meant it), writing 'flowchart' as a 'flawchart'. The term is perfect for those circular diagrams with arrows that are supposed to explain everything scientifically, but are completely without evidence and inevitably involve an identification of...

Those interviews from Croatia are brilliant, and very sad. The stories of the two interviewees deserve more publicity, I think. Thanks Mike, Ivan and J.

I've done the call, there were 3 women from NICE who were , well, very nice. They do genuinely want to make guidelines more useful. I guess that could mean that they are focused on the form rather than the substance, but getting form right is still an advance, and this team seemed to be trying...