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Why not classify patients according to whether or not they like Ryvita? You would then have gut-brain-Ryvita axis diseases. Very useful. Or Mac or PC users - that would produce something very interesting. You could use it in an advert.

I have added some citations and am hoping to get this in a form ready for publishing fairly soon. More thoughts welcome. I think there is still a bad paragraph at the end about ME/CFS being a 'fact' of a group of (ill) people when I have to admit that it is also a concept of a legitimate...

What a strange idea.

Many thanks for that. It shows just how much clearer the confusion was at the time and why it is time we caught up with the lesson that Acheson had already learnt thirty years ago. The irony is that they plumped for PVFS, which of course isn't any good either. It is interesting to see Acheson...

Absolutely. I think that official registration as a psychotherapist should be an immediate debarment from clinical practice.

I am putting this in this thread because it seems to be the most recent discussion of the relevant points. I was digging out references for a paper I am writing and looked back at Ramsay 1957. I was interested to find the paper attached below. Ramsay himself suggests that individual patients...

I think that is rather overestimating what she found. The levels of some rather obscure cytokines shifted a bit after about 3 years I think. Enough to be statistically significant maybe but nothing that we would normally take as relevant in clinical practice. When those data came out I was...

That is just a reflection of the NHS not being obliged to fund. When I started treating people with RA and lupus with rituximab the NICE guidelines did not approve it. So lots of people I could have treated didn't get treated. But when I managed to find some money somewhere I could treat some...

The NICE Guidelines are recommendations for best practice within the NHS. Health professionals retain the freedom to deviate from the guidelines it they consider it. in the patient's best interest. That really means two things. 1. The NHS is not obliged to fund the cost of anything outside the...

Apart from anything Garner has behaved in a totally unprofessional way. As a physician you do not malign members of the public, however pathological you may think their behaviour is. In fact the more pathological you think their behaviour is the more you should have sympathy and treat them...

It looks to me as if the climate of opinion and the policy making of specialties is at present so awful that there isn't a lot of point in hoping for a home. As Kitty says, we need a change in leadership. Maybe we have to wait for a science lead to raise physicians' interest.

There is a very important confusion going on here. Nobody will be suggesting that Garner did not experience what he experienced. What is suggested is that Garner's belief in the reason for his recovery is likely to be baseless because it does not fit even the facts in his case.

Hi @Friendswithme. I disagree with your analysis. (You are probably aware that I am a professor of medicine.) Paul Garner's behaviour has been absolutely terrible. The level of hypocrisy is astonishing. He is supposed to be an expert on evidence quality in medicine yet is prepared to tag his...

I think you might need to go to an Ann Summers shop.

Another thing that intrigues me is that Fox and Garner are Liverpool and so is Kell. Is there some local infighting involved in all this?

The thought of being intellectually inspired by Sharpe is intriguing. Almost medically unexplainable.

Maybe that is a different preparation. Their methods are not well described. But platelet aggregates would be spun out by centrifugation. Then the aggregation. would be ex vivo - however you try to play it. Why should they look bigger. I have sent years doing fluorescence microscopy. Things...

I think their argument is naive and simplistic. Thrombosis and embolisation depend both on fibrin polymerisation and platelet aggregation, and can be contributed to by bacterial material as in endocarditis and even immunoglobulin in various forms of thrombotic vasculopathy like visual loss in...

I agree. And to be honest this is a very good rate of funding in an area where there are no solid leads. Any other areas that get more like 20% funded will have well established avenues and tenured MRC fellows extending ongoing work. Putting it bluntly the figures do not such any bias - if...

Why? At least some of the bits stuff they showed were much bigger than platelets and would need to be to be of any interest in embolisation. Isn't platelet poor plasma plasma that has been spun hard enough to get rid of most of the platelets. Platelet Poor Plasma Centrifuge tube to obtain...