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It's great that he posted this indictment of himself from an academic colleague. And what has the "long retired" bit got to do with anything? :)

I'm not the slightest bit expert on trials nor medicine, but from what I've learned from this forum and PR, it really doesn't take too much nous to see some of the most blatant flaws that have been highlighted in PACE. And that's not at all just blind acceptance of what others have said. The...

Great news @JaimeS :)

As usual, a characteristic partial truth from MS, strongly implying an untruth. True: we reject the findings. Omission: the reason we reject the findings is because the science is dog poo. Implied untruth: we don't like the findings because we are biased.

There was a commenter responding to one of @dave30th's blogs (I think), who said they were in the GET arm of PACE, and when their heart rate went through the roof the staff tried to dismiss it as a faulty monitor because that result was not possible. Apparently annoyed when participant would not...

Surely it is mostly down to being open label with subjective self reported outcomes, compounded by what amounted to selectively applied propaganda.

OK, just suppose a PwME also has an element of deconditioning, because they are too ill to do much. So when MS says "the possibility that associated biological processes may be at least partially reversible", let's say he is talking about the deconditioning component of this person's biological...

Absolutely.

I remember a lifetime ago (almost) when us RAF apprentices had to go to a sort of "Sunday school" (cannot recall what it was called now), and someone asking "What if an all powerful being turned up who proved to be even more powerful than God?" The answer given by the vicar was along the lines...

Now wouldn't that be something. Yes, it sounds sensible that a good step will be to establish if the clonal expansion is in response to a real threat, or an autoimmune issue. Really promising line of research it would seem.

Yes I think he was trying to do that, but I don't think it worked.

"Is that what that says. Really?" Intriguing response to him seeing what was written in the very manual the PACE GET therapists followed. Almost as if MS is a bit surprised to see it out in the open himself, and not knowing how to react. My gut feeling is the PACE manuals could be their real...

As I've said in the past, I think most people model their world in terms of truths and untruths, and interact with others on that basis. But others, and MS very possibly, seem to model the world in terms of cause and effect, and interact with others primarily on that basis. I don't see his...

One thing for sure - something is definitely going on here ...

I would have thought malpractice to be a more likely thing to go for.

I think it is a reasonable and valid inference from the following quote in the article:- "Many patients with chronic fatigue syndrome are being held back by a ‘self-fulfilling prophecy’, according to a leading researcher. Oxford psychiatrist Professor Michael Sharpe said that some people with...

I would think that from our good-science perspective, it would be extremely sensible for someone very clued up from our side to talk to this person. It would either turn out that we've been wrong all along (extremely unlikely I think!), or we could get to the bottom of why these supposed success...

They got something right then :)

The shape of things to come? https://www.ncl.ac.uk/press/articles/latest/2018/05/first3dprintingofcorneas/ What will they be 3D printing next?

The link in post #2 has the info, but reproducing here: https://www.parliament.uk/edm/2017-19/1247. Still at 100.