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You may be interested to watch Alan Light's presentation from Dec 2018 Here is one of the summary slides In regard to mtDNA studies - my understanding from talking to others that just testing mtDNA is not sufficient - there are ~1000 nuclear genes that affect the mtDNA function

I promised myself I wouldn't enter BPS threads. Just a quickie here (makes me so mad) The UK has some fantastic biological research work going on with new researchers joining the fold. A good way to counter Sharpe is getting a story out about this. Here are five topics of the top of my head *...

My understanding is less than 50% of Sjogrens patients will actually test positive for SS-A or SS-B. It can take 10+ years for these to appear. Early Sjogrens antibody tests are available in the US and seem to pick up more positive tests. This article about the early antibodies is interesting as...

@Simon M @Chris Ponting Just in case you have yet to put it on your calendar Mark Davis is talking at 1:30pm EST April 4th at the NIH conference. https://custom.cvent.com/536726184EFD40129EF286585E55929F/files/b4e3acbbb5a145edae6748ffd273e744.pdf From what I remember from Ron Davis's talk there...

There was no mention of Suramin.

@FMMM1 If you go to the Agilent website you will see that the Seahorse is not approved for clinical use https://www.agilent.com/en/products/cell-analysis/seahorse-analyzers "For Research Use Only. Not for use in diagnostic procedures." In addition if you look at the raw data in Dr Cara...

Hi @Andy - are you able to remove the screenshot file uploads on my posts as Emerge don't want them shared :(. I noticed the Twitter conversation below recently posted (not me)

Last day focused on Treatments.These are the main highlights. Dr. Jarred Younger appeared in a video and talked about future PET/MRI studies looking for a cause for brain inflammation and try to identify activated microglia. Also he will decode data from large longitudinal studies looking at...

They have DNA data from 66 doctor qualified patients and ALL of them have at least one IDO2 potentially damaging mutation. Dr Phair said many patients sent him their WES/WGS genome data and 3 patients did not have one of the mutations but did have the Tyrosine pathway mutation that is the other...

Ron Davis stated yesterday that testing for RNA virus is really really hard to do so they were looking at parasites next. He spent some time explaining how they are developing tests to combine many samples while at the same time looking for multiple matches in their DNA tests. This helps with...

The second to last slide shows high PFOS levels in many patients. PFOS has been well studied and is known to affect the thyroid. e.g. Thyroid disruption by perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) .

Thanks @Andy. I still see them large on the browser I am logged in and posted with, but other windows where I am not logged in they are small. Maybe I have the images cached........ Next time I'll try and post thumbnails

Here are the glucose subset slides - 777 patients retroactively studied! 1. Glucose tolerance test n=22 split into three subsets Flat, Trunctated, Normal [Screenshot removed] 2. Retroactive analysis of 777 patient data [Screenshot removed] 3. How these 3 subsets related to other medical test...

One twitter user captured the environmental contaminants slide (because it related to previous posts by me on PFOS data in Maureen Hansons raw data)

I refreshed on two different browsers and it is there. I can try a different computer..... EDIT : I tried a computer not turned on for a few days and I see the same when I click on top right - event posts

I was blown away by Dr. Neil McGregors presentation. Identifying subsets by response to glucose, reasons for transcription changes, why amino acids are low, why the gut gets affected...... way too much to take in on one viewing. He covered soooo much in his hypothesis. Be interested in others...

For those that did not see it this was the thread for Michael Sikora's September 2018 presentation at the OMF Symposium that provided an update by the young researcher doing the actual work (posted by @Hutan) https://www.s4me.info/threads/stanford-community-symposium-2018-sikora-t-cells.6117/...

Maybe one of our New Zealand folks would like to contact Prof Tate to see if this spelling was intended or a typo. His contact detail is here https://www.otago.ac.nz/biochemistry/people/index.html#

In a 2018 video he said he was getting access to a Seahorse analyser for energy analysis - also mentioned in post #11

Oh no!!!!! Ugggghhhhhhhh. In his December video Karl Morten stated how he had no money to continue his very promising work. Ron Davis has said how hard it is to keep a team together without long term funding - people leave after you have spent time training them and them gaining knowledge...