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Section snippets Case Report A 59-year-old woman, Mrs. A, was referred for an outpatient telemedicine psychotherapy consultation in the department of neurology at a large academic medical center. Five years earlier, she had begun experiencing neurological symptoms including gait and balance...

Now published Increased Levels of Inflammatory and Endothelial Biomarkers in Blood of Long COVID Patients Point to Thrombotic Endothelialitis The prevailing hypotheses for the persistent symptoms of Long COVID have been narrowed down to immune dysregulation and autoantibodies, widespread organ...

News in Brief posts for w/c 15th May Facebook: https://www.facebook.com/sci4me/posts/pfbid02Fnzv69LPCoT44HgumvDSxFf1As9vqMNDbPz5F24aeBYXv7GmcAZDAJvoHc5bsrZxl Mastodon: https://med-mastodon.com/@s4me/110405693381471634

Full title: A systematic literature review on the clinical efficacy of low dose naltrexone and its effect on putative pathophysiological mechanisms among patients diagnosed with fibromyalgia. Highlights There is only low grade evidence to support that LDN reduces pain and improves quality of...

Background Successful management for functional neurological disorder (FND) requires multidisciplinary involvement starting with providing a definitive diagnosis. Objectives To observe clinical management of patients with FND during hospital admission. Methods A prospective observational study...

"criteria for CFS" = Fukuda

Background: Limited published data suggests that absence of uplifts (minor pleasant events) is associated with clinical worsening in patients with chronic fatigue syndrome (CFS). The current study aimed to assess the relation of illness worsening to the trajectories of social and non-social...

"This report analyses survey responses from ten NHS Health Boards in Scotland to understand delivery of ME/CFS services, implementation of the updated ME/CFS NICE guidelines, barriers and opportunities to implementing the guidelines, and options for future ME/CFS service development."...

The funding notice. Digital Health: Innovative engineering technologies to improve the understanding and management of fatigue Fatigue is considered as a "final common pathway": a vague clinical symptom that can result from many different diseases and mechanisms. Our limited understanding of...

Exhausting search for solutions to UK’s sharp rise in tiredness "Rosalind Adam, an Aberdeen GP, and her colleagues are dealing with more people than ever reporting extreme tiredness, even taking into account their increased workload. “The thing is, we are seeing so many patients a day now,” she...

Innovative research using AI led by the University of Aberdeen aims to find better ways of managing and treating fatigue. Many people struggle with fatigue which can be the result of medical conditions like long covid, stress or simply because of modern lifestyle. This makes it difficult for...

In late 2010, an outbreak of Cryptosporidium hominis affected 27,000 inhabitants (45%) of Östersund, Sweden. Previous research shows that abdomen and joint symptoms commonly persist up to 5 years post-infection. It is unknown whether Cryptosporidium is associated with sequelae for a longer...

"Several ‘maladaptive’ cognitions and behaviors (e.g., catastrophizing cognitions and avoidance behavior) have been associated with higher symptom burden in pain syndromes and FSS such as chronic fatigue syndrome, irritable bowel syndrome and fibromyalgia" "The questionnaire was validated in...

Highlights Maladaptive cognitions and behaviors were associated with somatic symptom severity over five-year time. Associations were also found for maladaptive cognitions and behaviors and reduced physical and mental functioning. Also, within subjects cognitions and behavior may play a role...

Why is COVID life-threatening for some people? Genetics study offers clues "Baillie and his colleagues analysed data from more than 24,000 people and combined this information with data sets from around the world. They found 49 DNA sequences that are associated with becoming critically ill from...

Abstract Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown1 to be highly efficient for discovery of genetic associations2. Despite the advanced stage of illness at presentation, we have shown that host genetics in patients who...

They also looked at plasma immune molecules in that study, and many of the authors were listed for both papers, so at a quick look I don't think so.

Highlights The stress-Multiple Sclerosis (MS) relationship is controversial, with low evidence. The bidirectional hypothesis was confirmed through ecological momentary assessments. Active coping was adaptive with high stress, but counterproductive with low stress. Low-trait anxiety was...

Did what I could last night to promote this conversation.

Common viral antibodies could trigger MS, research reveals “We have discovered that certain antibodies against the Epstein-Barr virus which would normally fight the infection can mistakenly target the brain and spinal cord and cause damage.” ... "EBV is one of the most widespread viruses in...