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"Post exertional malaise During the development phase, the trial team were contacted by several organisations representing the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) community with concerns relating to the potential harms of unsupervised vigorous exercise for people with...

Could explain why I experience bowel movements slowing or stopping outright while in PEM.

Abstract Background: Clinical investigations of long-term effects of coronavirus disease 2019 (COVID-19) are rarely translated to objective findings. Objectives: To assess the functional capacity of individuals reported on deconditioning that hampered their return to their pre-COVID routine...

Full title: Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/coronavirus disease 2019 (COVID-19) pandemic...

Published papers thread for w/c 20th Feb. Facebook: https://www.facebook.com/sci4me/posts/pfbid03RzM1tpPB8RRow1oyMk9La3TzNrCfJJA7HXp6b1drwKEQgumDyw5ixbdH46YDhpfl Mastodon: https://med-mastodon.com/@s4me/109935875767105617

News in Brief posts for w/c 20th Feb. Facebook: https://www.facebook.com/sci4me/posts/pfbid02rvV5mtZfQMa6wyWMYZSnih4r6KRyUPQgwd8GGc8GU7uFa8NYNwyCGU97pFz6meybl Mastodon: https://med-mastodon.com/@s4me/109931142704953144

What you need to know Tachycardia on standing or minimal exertion may occur after covid-19 and may cause substantial functional impairment When assessing a patient with tachycardia, consider potential causes including autonomic dysfunction Measures to reduce tachycardia can greatly improve...

Full title: Non-pharmacological interventions for self-management of fatigue in adults: An umbrella review of potential interventions to support patients recovering from critical illness Highlights • Self-management is effective for fatigue caused by physical conditions. • Self-management for...

Abstract Long-COVID syndrome is associated with high healthcare costs, but its pathophysiology is not yet fully understood. Inflammation, renal impairment or disturbance of the NO system emerge as potential pathogenetic factors. We aimed to investigate the relationship between symptoms of...

"2.1. Patients and Controls Patients were included in the study if they met all three of the most commonly used sets of ME/CFS diagnostic criteria (Fukuda et al. (1994) CFS criteria [12], the Canadian Consensus criteria of ME/CFS (2003) [13], and US Institute of Medicine, now called the...

Abstract Recent studies provide some evidence for the contribution of antibody-mediated autoimmune mechanisms to the nature of fibromyalgia (FM) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Much attention was paid to the autoantibodies (AAb) targeting G protein-coupled...

Abstract Objective The primary objective of this article was to systematically review the prevalence of somatic symptoms in patients, healthcare workers and general population during the COVID-19 pandemic. The secondary objectives were to record the association between somatic symptoms and...

Background Residual somatic symptoms (RSS) are common in depressed patients, predicting treatment effectiveness. However, sex differences in RSS have received little systematic study. This study was conducted to compare sex differences of RSS in patients with first-episode depression (FED)...

Correction: Defining the minimally clinically important difference of the SF-36 physical function subscale for paediatric CFS/ME: triangulation using three different methods The original article [1] required an amendment to the Quantitative Data statement in the Ethics Declarations section. The...

Background and purpose: The coronavirus disease 2019 (COVID-19) has been associated with olfactory dysfunction. The persistent symptoms of anosmia or hyposmia were associated in previous studies with the development of memory impairment and mood disturbances. We aimed to investigate the...

Background: The long-term sequelae after COVID-19 constitute a challenge to public health and increased knowledge is needed. We investigated the prevalence of self-reported persistent symptoms and reduced health-related quality of life (HRQoL) in relation to functional exercise capacity, 6...

Trial By Error: An Upcoming “Biopsychosocial” Long Covid Conference in Finland "What is it with the health care establishments in northern Europe? Why are they so devoted to non-evidence-based approaches to treating serious medical conditions? Why do they trust arguably fraudulent research...

Yeah, but then their argument would be that structural changes prove the validity of the FND diagnosis. It doesn't have to make sense, they just need to repeat it often enough.

The first suggestion of it that I spotted on this thread, Coronavirus - worldwide spread and control, from Jan 26th 2020.

Abstract Paroxysmal exercise-induced movement disorders may be caused by energy metabolism disorders, such as Glut 1 deficiency, pyruvate dehydrogenase deficiency or mitochondrial respiratory chain disorders. A 4-year-old boy with a history of febrile seizures presented with paroxysmal...