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That has been tested and has consistently failed to deliver any real explanatory or therapeutic power.

The amount of money available seems to be falling everywhere. Prices are up here, incomes are no longer rising fast enough to keep up with them, and job security is falling.

Another acronym for the list.

Call me crazy, but have doctors considered not pretending they have an answer when they don't, and to stop dishing out psycho-drama morality-play crap as a substitute, and just making things a whole lot worse? Find a little humility. And a whole lot more than that.

Yes. :(

Especially in trials explicitly using techniques to pressure persuade patients to change their self-report responses. That is an open recipe for massive bias and confounding. Just about guarantees it, in fact, which is why the psychs are so keen on it, I guess. A reminder of this, from the...

Yes, but a non-linear one. Which is where the real problem lies, because humans are really bad at understanding and managing non-linear phenomena.

Medicine as Emoji. Discuss.

Being sicker has more adverse consequences across all measures. Who knew?

Sounds dodgy to me. Exposed warm ankles can lead to mixed dancing. :nailbiting:

That is... appalling, bordering on insane. :nailbiting: :grumpy: Even God rested on the 7th day.

Exactly. Excessive compared to what? If anything, ME patients are under reporting the situation. Partly because it is very difficult to describe, and partly because the rest of the world has makes it clear they don't want to hear it and will seriously misinterpret what you say. And that has...

Patients using accelerometers for 4 weeks strongly refutes the claim by PACE that they are an undue burden for patients.

They are utterly without shame, concern, or remorse. Anybody who thinks the criticism of them is harsh has not understood the problem. They are not only not being held to proper account, they are being actively rewarded for their wilful negligence and misconduct.

One of my greatest fears is that the symptoms of ME mask the early non-specific symptoms of other serious diseases, and hence delay diagnosis and treatment, and potentially worsen prognosis. And that is before adding in the problem of having an ME/CFS diagnosis introducing a psychosomatic bias...

Best I can tell volition/drive is not impaired or pathological in ME. What is impaired or pathological is the consequences of engaging it, of putting it into action. The urge to be active and involved in life is not diminished, but the capacity to do so is, often to the point of being...

Getting a bit tired of these kind of critiques focusing on the pharmaceutical industry. Whatever their dodgy practices might be, at least their claimed treatments have the advantage of actually being amenable to proper blinding/placebo control. e.g. Rituximab. Needs to be a lot more focus on...

Right question.

Yep. Gross and fine patterns.

Researchers need to stop making claims, and stick to reporting methods and results.