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  1. Valentijn

    Cellular bioenergetics is impaired in patients with CFS (2017) Tomas, Strassheim, Newton et al

    Not really ... there is impairment, regardless of cause. Fatigue is a symptom. Symptoms are caused by a disease or other states. Symptoms are not caused by symptoms, though multiple symptoms may have the same source. So I don' think it makes any sense for a state to be a symptom of a...
  2. Valentijn

    Friday 10 Nov, 7:10 pm (UK time): Livestream of Netherlands showing of Unrest Q&A with David Tuller, Charles Shepherd

    Obviously they were just accommodating the patients who had to lie down to watch :D But it got fixed after a few minutes.
  3. Valentijn

    Exercise-induced changes in cerebrospinal fluid miRNAs in Gulf War Illness, Chronic Fatigue Syndrome and sedentary control subjects, 2017, Baraniuk

    The ICC and CCC both have neurological symptoms in their diagnostic criteria, and the ICC includes GI symptoms as well. SEID includes cognitive impairment, which would probably be classified as neurological.
  4. Valentijn

    Exercise-induced changes in cerebrospinal fluid miRNAs in Gulf War Illness, Chronic Fatigue Syndrome and sedentary control subjects, 2017, Baraniuk

    Not sure why they excluded neurological and GI symptoms from the CFS group, however. Are they using Fukuda still?
  5. Valentijn

    Cellular bioenergetics is impaired in patients with CFS (2017) Tomas, Strassheim, Newton et al

    Indeed, correlation does not prove causation, and the authors address this point in the Discussion: But it's pretty well established via 2-day CPET, and listening to any patient, that onset of the disease precedes a lack of exercise. So while it's possible some abnormalities might be more...
  6. Valentijn

    Esther Crawley talk at TEDxBristol, Thurs 2nd Bristol - "Disrupting Your View Of ME"

    A lot of us have trouble watching videos. Especially ones which might induce nausea or cause us to hurl objects at the screen :-P
  7. Valentijn

    Opinion on "ME/CFS Service", UK

    I think this is a very important point, in that patients should be entitled to symptomatic treatment by the relevant specialists as a fundamental function of any health system: And a very good argument in favor of getting rid of the bullshit CFS services, even the ones which aren't actively...
  8. Valentijn

    BBC: I made a film from my bed to prove my illness is real - Jen brea

    They never allow comments on any of their articles, as far as I know.
  9. Valentijn

    Lactobacillus gasseri - miracle probiotic for weight loss?

    That would explain some of their fundamental errors involving basic scientific concepts :-P
  10. Valentijn

    Lactobacillus gasseri - miracle probiotic for weight loss?

    Unfortunately this seems to be an ad which their site has created for an affiliate which pays them revenue to promote their product. I think it would be more productive to discuss the specific research, and leave the ad (and traffic to it) out of the equation :-P
  11. Valentijn

    Esther Crawley talk at TEDxBristol, Thurs 2nd Bristol - "Disrupting Your View Of ME"

    It might indicate a wider pattern of warping reality to garner support.
  12. Valentijn

    Dare to hope... what amazingly great thing might happen in S4ME's first year?

    I hope to see the relevant BPS "researchers" face professional consequences for their active campaign against ME patients. They've said some awful things about us, and implied a lot more, and I'd like to see them held accountable, preferably unable to get a job at any reputable institution, and...
  13. Valentijn

    Question concerning XMRV

    http://iv.iiarjournals.org/content/27/2/177.full
  14. Valentijn

    What can a CPET do to diagnose ME, OI, mitochondrial disease, heart conditions, etc.?

    I don't think it's specific enough by itself. But a bad enough value on a single CPET does exclude deconditioning/sedentary lifestyle. It also could depend on what else is being measured at the same time. My specialist is also a cardiologist, so did an ECG with my CPET. Combined with tests...
  15. Valentijn

    Question concerning XMRV

    Yes, I wasn't impressed with one of the studies which claimed to disprove XMRV involvement. And the way some parties used the disproving of XMRV involvement to support their claim that ME is psychosomatic was particularly distasteful. But the other studies debunking XMRV were methodologically...
  16. Valentijn

    Pirate paper website Sci-Hub dealt another blow by US courts

    It probably won't ... US courts can't enforce their judgements in other countries. Some might opt to cooperate, but many would not. Even countries friendly with the US recognize US copyright law as being ridiculous in general. Sci-hub has domains in several countries - they'd have to all be...
  17. Valentijn

    Question concerning XMRV

    There have been a couple studies which use multiple methods to test for a retrovirus. One method indicates there is a retrovirus, but more specific methods indicate there is not. Basically viruses are strings of DNA (or RNA in the case of a retrovirus). We have tons of DNA and RNA in our...
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