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Probably needs a mountain of salt, as this review includes John Ioannidis, who has been critical of Cochrane for all the wrong reasons. Although none of this is a surprise to us, the few Cochrane reviews published on subject matters that are known to this forum all fail to meet minimal...

Full title: Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis https://www.sciencedirect.com/science/article/abs/pii/S0895435622001007 Highlights • In this large sample of 1567 interventions...

I see sporadic discussion of this. One particular way is from LC deniers who want to attribute everything to psychology and so focus obsessively on previous "mental health" worsening, but since it applies to known physical disabilities, and how so much of "mental health" labels are actually...

This obsession with linearity is weird. The idea that a disease should follow a linear script and never deviate from it has no basis in reality, that every step should either be predictable, or assumed to be a positive feature of some imagined principle is completely irrational. Medicine is...

It's boom time in the industry, they're selling the hottest (fashionable) cakes.

To clarify: the interest I see is mostly about the immune downregulation it implies and the CCR5 receptor, rather than the drug. But this is above my tiny understanding of biology.

Probably. But you probably have to be sick for that, not "sick". If it's rejected as a disease, by definition it can't be an occupational disease.

This seems excessive even in the worst case. If true, this is incredible, and unsustainable. OK this is clarified in a response: it's 40% of healthcare professionals who developed Long Covid. So 40% of healthcare workers who got LC from the first wave have been fired.

This paper is getting more noise and attention than usual.

In an exploratory trial treating “long COVID” with the CCR5-binding antibody leronlimab, we observed significantly increased blood cell surface CCR5 in treated symptomatic responders but not in nonresponders or placebo-treated participants. These findings suggest an unexpected mechanism of...

The problem with that is: what's stress? A quick look at various definitions and it's something like "the body's response to threats". It's one of the most vague concepts that's ever been put to such widespread use. It basically means anything and everything, especially as it's so commonly...

Moved post. This thread collects together several threads on the same topic. Cryptocurrency investors (well, in this case inventor) are contributing more to researching a major health crisis than all medical institutions combined. The UK's NIHR funding was mostly wasted on pet projects and the...

Oh, no "almost" there. It is as clear and blatant dereliction of duty as it gets, entirely debunked and continuing only by coercive statutory force fueled by ideology. The consequences are the same as recommending that we should end everything about Parkinson's disease and re-classify it as a...

The most annoying thing about this is that this is all stuff the patient community figured out and essentially taught to medical professionals. All this stuff was discussed in patient forums within the first months, mostly because of fellow chronically ill folks jumping in to help. All this is...

Ideology sure is a powerful drug. How does that even follow? Make any sense at all? Do they think trying twice as hard will do it? Just keep trying the same key for the wrong lock, maybe one day the lock will just give up, have pity and open up anyway. This is an infinite loop of failure. The...

How often does a response over NICE guidelines includes this line? Because it's always there for the ME guidelines, obviously admitting they are not enforcing anything. And since enforcement is 99% of any system of rules... Maybe the questions need to include the fact that the services are...

My favorite thing about papers like this is that according to the caricature invented for the biopsychosocial model, we should be all over this. "It drains the lymphatic system!" sounds medical and technical and biological and stuff. We should be gushing over this, or whatever. It validates the...

post copied to the WHO news thread COVID-19 technical lead at the WHO. Has mentioned LC a few times before. I am not aware that the WHO has actually done anything beyond thoughts and prayers. Maybe they can't, it's not clear. On this it seems more like the UN, club members can choose to listen...

Post copied from the Long Covid in the media and social media thread COVID-19 technical lead at the WHO. Has mentioned LC a few times before. I am not aware that the WHO has actually done anything beyond thoughts and prayers. Maybe they can't, it's not clear. On this it seems more like the UN...

I don't know, feels like a discredited scientist should not continue to have unearned promotions and titles. But that's just me, weird person who thinks pseudoscience is bad and charlatans should not be rewarded just because the pseudoscience he still promotes is popular. I will gladly hold an...