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  1. ME/CFS Science Blog

    Blog: ME/CFS Skeptic: 2022: "Looking back at a year of ME/CFS research"

    Thanks. To be honest I'm not the best at dissecting biomedical studies. Much of the biology and techniques goes over my head. But I thought an overview of the most significant studies of 2022 would be useful for others, even if we could only briefly summarise the findings without explaining them...
  2. ME/CFS Science Blog

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    This is the sample size determination as stated in the paper. "For 99% confidence interval and 0.05 significance, our sample size calculation is n = z2×p (1− p) / ε2 = 1.282×0.99 (1− 0.99) / 0.05^ 2 = 7. Z is the z score, which is 1.28 for power 0.8; p is the population proportion. For 99%...
  3. ME/CFS Science Blog

    Elevated ATG13 in serum of pwME stimulates oxidative stress response in microglial cells , 2022, Gottschalk et al

    Did anyone get a reply about this inconsistency? Below is figure 3.A as used in the paper: And this is my own plot of the data shown in table 1:
  4. ME/CFS Science Blog

    MedWatch: "We see a radicalization of the scientific debate"

    The website describes itself as follows: "The MedWatch team scans the net for dangerous and dubious promises of healing. One focus is on research from the grey area of the net, in which alleged healers offer their miracles. MedWatch reports and clarifies." https://medwatch.de/was-ist-medwatch/
  5. ME/CFS Science Blog

    MedWatch: "We see a radicalization of the scientific debate"

    The journalist conducting the interview is Martin Rücker who also tweeted about an upcoming critical commentary on the NICE guideline.
  6. ME/CFS Science Blog

    MedWatch: "We see a radicalization of the scientific debate"

    ... MedWatch: As a professor of psychiatry, how do you view the causes of Long Covid and ME/CFS? Walter: 15 years ago, I would probably have classified fatigue as psychosomatic. With today's knowledge, however, we can see that there are a high probability of organic causes. A majority of...
  7. ME/CFS Science Blog

    MedWatch: "We see a radicalization of the scientific debate"

    This interview with Professor of psychiatry Martin Walter also discusses ME/CFS and the IQWiG draft report in Germany. The title and quotes below are translated with Google Translate. At Jena University Hospital, Martin Walter, head of the Department of Psychiatry and Psychotherapy there...
  8. ME/CFS Science Blog

    Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2022, Petter, Scheibenbogen, Wirth et al

    I think they did. They write: "Healthy controls... were required to have sedentary jobs and perform less than three hours of physical activity per week." But I agree that this likely does not fully control for the inactivity and deconditioning of ME/CFS patients. EDIT: the authors write in...
  9. ME/CFS Science Blog

    European ME Coalition:Press release: EU supports research on poorly understood diseases

    The 25 million is not only for ME/CFS but for research on high-burden, under-researched medical conditions. So there will likely be fierce competition amongst these research fields. ME/CFS researchers will have to collaborate and submit a competitive proposal otherwise it could be that the funds...
  10. ME/CFS Science Blog

    Which scientists and research groups would you want to bring to the ME/CFS research field

    I think we might have one on our forum here. The bird-watching guy.
  11. ME/CFS Science Blog

    Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort... 2022 Parker et al

    No control group, only 31 participants and the authors seem to have made up the intervention and the main outcome, the Leeds PESE Questionnaire (LPQ). The questionnaire is available in the supplementary material.
  12. ME/CFS Science Blog

    Which scientists and research groups would you want to bring to the ME/CFS research field

    Suppose that you could lure research groups into studying ME/CFS, who would you like to bring to this field? Are there any top biomedical researchers who stand out or who have an expertise that might particularly suited in studying ME/CFS? Or: who are the most respected medical researchers that...
  13. ME/CFS Science Blog

    OpenAi's new ChatGPT

    I'm already using this AI over Google Search if I want information or an answer for something.
  14. ME/CFS Science Blog

    Severe myalgic encephalomyelitis/chronic fatigue syndrome in children and young people: a British Paediatric Surveillance Unit study 2022 Crawley et a

    If patients with severe ME/CFS don't see a pediatrician but another specialist instead or if the physicians don't diagnose these patients correctly, the estimate could be off by orders of magnitude.
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