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Available on the CC Register on left hand column "Accounts and Annual Returns" pdf =...

The data set would have included various demographic information and the study method merely involved interrogating the data set at two time periods. Predictor in this sense is simply which column/row headings appeared against the results of running the equation "data set two, minus data set...

Cognition, emotion, and the central autonomic network Lisa Quadt, HugoCritchley, YokoNagai https://www.sciencedirect.com/science/article/pii/S1566070222000078?dgcid=coauthor Abstract The demands of both mental and physical activity are integrated with the dynamic control of internal bodily...

To quote one wife of my acquaintance, whose husband had ME/CFS - "I got fed up with him lying in bed all day so I sent him back to his mother" There aren't good stats but there's a lot of anecdotal views about the role of illness as a basis for divorce, and statistically women are more likely...

When they write "nociplastic pain and healthy anger regulation demonstrate inverse patterns of activity in the medial prefrontal cortex and amygdala" I don't think the researchers are claiming a causal link between anger and pain, the way I read it is: they are saying that the flow of activity...

Nociplastic pain: towards an understanding of prevalent pain conditions https://pubmed.ncbi.nlm.nih.gov/34062144/ Abstract Nociplastic pain is the semantic term suggested by the international community of pain researchers to describe a third category of pain that is mechanistically distinct...

The smoking link is not related to stomach acid per se but to the impact smoking has on the esophagus and the lower esophageal sphincter. There's of research on the role of collagen - the idea being that smoking causes changes in collagen which reduces the effectiveness of the sphincter so it...

Effects of aging and gastritis on gastric acid and pepsin secretion in humans: a prospective study Abstract Background & aims: Recent studies suggesting that gastric secretion does not decrease with aging included few elderly individuals and measured only acid secretion. The aims of this...

Laparoscopic Nissen Fundoplication is not without risk, though it seems pretty safe. In addition to the usual risk of complications of surgery, the operation is not always wholly successful and reflux can persist, or the tightening can be too great and remove the ability to vomit or belch, that...

The Phd award started in 2019 so NICE 2021 wouldn't apply. Still raises the question about whether patients were involved in the study design (I'd bet on No !) I usually manage to be generous in my thinking to almost any area of study (yes even psych) but this one really irritates me. The way...

The PhD candidate: Miss Tarnjit Sidhu https://www.research.manchester.ac.uk/portal/en/researchers/tarnjit-sidhu(9491d41d-e390-43cf-8af5-69e7bef36311)/publications.html "Tarnjit Sidhu is an MRC DTP PhD student within the department of Psychology and Mental Health. Her research explores the...

The PhD candidate: http://www.bris.ac.uk/cdt/digital-health/people/current-students/lauren-thompson/

https://www.mycoted.com/Assumption_Surfacing Assumption Surfacing The aim of this technique is to make underlying assumptions more visible. Identify a particular choice you have made, and ask yourself why you feel it is the best choice – i.e. what assumptions guide this choice. List the...

Yes previous connection to Cochrane probably should have been highlighted somewhere in the publicity around the NICE/CC closer ties arrangement. I guess it would have been common knowledge to all the sector insiders, nevertheless it would have been good form simply to have added a line noting...

nod to @FMMM1 https://www.s4me.info/threads/nice-and-cochrane-sign-collaborative-agreement-to-deliver-%E2%80%98living%E2%80%99-guideline-recommendations.22209/page-6#post-403075 Gill Leng is to become the Chair of Guidelines International Network (GIN) https://guidelines.ebmportal.com/

Second author also contributor to paper discussed here: https://www.s4me.info/threads/the-role-of-evidence-based-guidelines-in-the-diagnosis-and-treatment-of-functional-neurological-disorder-2021-tolchin-baslet-carson-perez-stone.23788/

Long COVID is a non specific term covering a whole raft of clinical entities. "And the rest" is a fair comment given that Long COVID means a whole lot of different things - at this stage of knowledge and perception, a whole lot of things to different people. I don't think that saying Long COVID...

Some ISPs are making it difficult to access Scihub. I don't know what other work arounds there might be but I use a VPN set to match to the specific Scihub domain. This site gives the current domains: https://sci-hub-links.com/ Actually I've just tried it on TOR - and works find. A bit of...

Added seconded of these references to the forum: https://www.s4me.info/threads/eeg-source-analysis-of-chronic-fatigue-syndrome-2010-flor-henry-et-al.24276/ Link to full article = https://sci-hub.se/10.1016/j.pscychresns.2009.10.007

Although published as psychiatry paper, this does seem to be pathophysiologically based. 5. Conclusion Thus, it would appear that dysregulation of the cortical hemispheric controls of immunological functional systems (left hemisphere) and hypothalamic–pituitary–adrenocortical axis is the...