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    The Reproducibility Movement in Psychology, 2022, Ashburn -Nardo et al

    Introduces a new notion, the "reproducibility movement", seeks to use gender as a source of victimhood for researchers - refs the case of Amy Cuddy: https://www.thecut.com/2017/04/amy-cuddy-death-threats.html and although the authors acknowledge their hypothesis falls, manage to construct an...
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    The Reproducibility Movement in Psychology, 2022, Ashburn -Nardo et al

    Frontiers Psychology, 13 June 2022 The Reproducibility Movement in Psychology: Does Researcher Gender Affect How People Perceive Scientists With a Failed Replication ? Leslie Ashburn-Nardo, Corinne A. Moss-Racusin, Jessi L. Smith, Christina M. Sanzari, Theresa K. Vescio and Peter Glick...
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    News from Doctors with ME

    The reason I said above that I though it was a clever piece of work is precisely because of the language. I may be over crediting the creators but it seems to me to be set in exactly the legal and managerial language of the NHS and therefore challenges the rule breaking as identified in...
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    News from Doctors with ME

    I think this may deserve a thread of its own. I've only listened to a small part and while the "management speak" is sometimes off putting, this looks like a very clever piece of work
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    Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci, 2022,Hajdarevic et al

    It's difficult to exclude correlation. If PEM is mediated by an elapse of time - it is classically described as occurring many hours after an assumed precipitating activity/event - then in any individual where onset of PEM is perceptible after an elapse of time which includes the usual sleep...
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    Altered Effective Connectivity of Resting-State Networks by Tai Chi Chuan in CFS Patients: A Multivariate Granger Causality Study, 2022, Li et al

    People who can take two one hour long Tai Chi lessons a week and practice at home for 30 minutes each day have an improved health related quality of life by doing Tai Chi compared to not doing Tai Chi. MRI scans showed some areas of the brain glowed a bit more after a month of Tai Chi, in people...
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    Increased risks of cancer and autoimmune disease among the first-degree relatives of patients with ME/CFS, 2022, Moslehi et al

    AD variation runs in families so looking for an association for ME/CFS in first degree relatives risks picking up familial groupings with high AD prevalence but which are only randomly associated with ME/CFS. How do autoimmune diseases cluster in families? A systematic review and meta-analysis...
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    Increased risks of cancer and autoimmune disease among the first-degree relatives of patients with ME/CFS, 2022, Moslehi et al

    A limitation of using first degree relatives is that without specific analysis it is difficult to separate social, behavioural and environmental features from purely genetic factors. Each family unit tending to have the same access to healthcare, same dietary habit, same addictive habits, same...
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    "There were sustained high levels of presentation [at emergency depts]...the majority of whom were older people who were “deconditioned”"-Health boss

    Broadly there are four domains where 'deconditioning' is a valid term - old age, prolonged immobilisation, athletic injury and space flight. In the case of athletic injury unless the athlete suffers prolonged immobilisation, deconditioning is a purely relative process and there is no...
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    "There were sustained high levels of presentation [at emergency depts]...the majority of whom were older people who were “deconditioned”"-Health boss

    No shortage of relevant papers from a Google Scholar search on "deconditioning in older people", the term has been in use for at least 20 years. Deconditioning in old age seems fairly well defined, and has a clear association with 'frailty'.
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    UK Parliament: ME/CFS Announcements: Statement by Health Secretary Sajid Javid, 12 May 2022

    Contrast and compare: Dr M C Sharpe MRCPsych Clinical Lecturer, Department of Psychiatry, University of Oxford Dr L C Archard PhD Senior Lecturer, Department of Biochemistry, Charing Cross and Westminster Medical School, London Professor J E Banatvala MD Professor of Virology, Department of...
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    Nature: A preoptic neuronal population controls fever and appetite during sickness, 2022, Osterhout et al

    A preoptic neuronal population controls fever and appetite during sickness Osterhout, Kapoor, Eichhorn, Vaughn, Moore, Ding Liu, Lee, DeNardo, Liqun Luo, Xiaowei Zhuan, Dulac Abstract During infection, animals exhibit adaptive changes in physiology and behaviour aimed at increasing...
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    UK Parliament: ME/CFS Announcements: Statement by Health Secretary Sajid Javid, 12 May 2022

    Crawley (post PACE) has received the largest total amount of NIHR ME/CFS funding (£2,832,750.28), however SMILE itself wasn't supported with NIHR funds.
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    UK Parliament: ME/CFS Announcements: Statement by Health Secretary Sajid Javid, 12 May 2022

    The post PACE NIHR funded ME/CFS studies are listed in this thread: https://www.s4me.info/threads/funding-of-me-cfs-research-in-the-uk.2533/#post-406747 I don't know if any have been subject to outcome switching. PACE of course was notable for OS, PACE was part funded by NIHR, MRC and the Dept...
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    UK Parliament: ME/CFS Announcements: Statement by Health Secretary Sajid Javid, 12 May 2022

    There is some recognition within the NHS and NIHR that it needs to change - a 2017 document pdf = 12 Actions to Support and Apply Research in the NHS from which: "Engaging with patients and charities, we will articulate more clearly what are the NHS’s national and local research priorities...
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    Mental health and alcohol use among patients attending a post-COVID-19 follow-up clinic: a cohort study, 2022, Broughan et al.

    AUDIT-C has been around since 1989 - AUDIT-C for Alcohol Use and is the basis for the current NHS Primary Care questionnaire: Alcohol Questionnaire - NHS AUDIT-C limitations: "AUDIT-C is a 3-item alcohol screen that can help identify persons who are hazardous drinkers or have active alcohol...
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    ME/CFS services in the United Kingdom

    I think in the context it means this: from: Section 10: Using health and social care information –direct care and indirect care purposes "The term ‘indirect care’ is defined as activities that contribute to the overall provision of services to a population as a whole or a group of patients...
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    UK Parliament: ME/CFS Announcements: Statement by Health Secretary Sajid Javid, 12 May 2022

    Short and unhelpful answer is "no". The difficulty is not so much around "genuine interest and understanding of ME" but what a Neurologist (or any other specialist) is paid to do. If a specialist is not contracted to see ME/CFS patients then they will not be on a referral list and there would...
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    UK Parliament: ME/CFS Announcements: Statement by Health Secretary Sajid Javid, 12 May 2022

    The problem I think is not that there would be a change of direction but that a new incumbent would simply not be interested, signaling to Civil Servants and NHS management that the priority for action on ME/CFS is reduced. Just for the record - following yesterday's vote the Government stays...
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    UK Parliament: ME/CFS Announcements: Statement by Health Secretary Sajid Javid, 12 May 2022

    I'm mindful that politics is not a subject for these forums but for those outside the UK (or those in it for whom the daily news is unbearable) who may not be aware, there is to be a no confidence vote on the UK Prime Minister by his Conservative Party colleagues Ballot win Boris Johnson doesn't...
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