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Yup. It's OK, Wes, we have one here. And maybe try to reduce the spread of the virus and remember that the virus is probably only here because of empire-building by scientists.

Yes but does it help to divide vrooming into active vrooming, functioning vrooming and vrooming behaviour?

Probably as much as anything.

I think it is fairly unusual.

My understanding is that Hemsley is more directly in charge of the development process, although I don't know exactly how. I did not get anything back from Dr Strain when I was discussing this before.

I agree. But I have been having conversations with various people involved in charities and the patient community for nearly a year (including copying in David Strain) and so far have not had any inkling as to what the protocol might be. When I talked with Sonya I didn't;t get the impression she...

Kupffer cells (interesting to see how spellchecker handles that!) get activated through various surface receptors for immune complexes, other material attached to complement, lipopolysaccharide on bacteria (CD14 complex), other toll-like receptor ligands and probably through cytokines like TNF...

Maybe we need a Dubbo brainstorming session. I should look t it again. I am a bit occupied with other things for a bit but then that is always the case!

Maybe we just have to find a pharmacological agent that blocks the negative signal specifically and show that it makes people suddenly feel fine, like the dopamine analogs do for Parkinson's or pyridostigmine for myasthenia. I doubt it would be that easy but even if there was a clear effect with...

I don't think we know the scatter pattern. All that was said was that only a tiny percentage had levels above the chosen normal range. Things get complicated here @chillier !! Inflammation is defined as an increase in vascular calibre, permeability to water and solutes and whitecell...

Something I think we may have not twigged to is that low level inflammation might be a risk factor for developing ME/CFS, just as acute infection is. So the diagram goes: Inflammation + ?? >>> ME/CFS Not ME/CFS >>> inflammation This is my central worry with the Beentjes paper.

Younger is showing CRP in mg/L. The normal controls are not a healthy population. Almost all should be below 3 and the majority below 2. We seem to be back to an indication that people with ME/CFS may have slightly raised CRP suggestive that there probably isn't any actual inflammation (if...

Younger's description of levels are reasonable. Except that for thirty years I worked with something more like. In mg/L <1 definitely no evidence of inflammation 1-2 probably OK 2-5 a little suspicious of inflammation but for many people can be taken as normal (note that the problem is that...

Or just celibate, so they don't get exhausted.:(

Two legs good then after all I guess.

Always happy to oblige.

I doubt these results mean anything at all. I like the comment 'particularly CD4 and CD8 T cells'. That is a bit like saying something affects 'particularly men and women'.

Do you know if that is mg/Litre or mg/decilitre? Both units have been used. I think everyone maybe going over to mg/Litre - which makes a level of 10 equal to the old level of 1.

Actually, the more one thinks of this the more complicated it may get. I remember in post EBV fatigue that I thought I could try stuff and then felt feeble and wretched if I did. With post Covid fatigue I just feel there is no way that I can try stuff. Moreover, if I do, I just feel more of the...

You are being very polite @rvallee. Are there some new forum rules ?;) This seems to be a muddle of opinionation and self-congratulation by some psychologophiles. The physician is pulling all sorts of rare stuff out of a top hat to impress the therapists, who are loving the love-in atmosphere...