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I digged deep because I was having trouble finding it, and it looked like I had indeed misremembered. They helped recruit and hosted webinars for a dodgy “stem cell” study, but they never funded it. See this thread...

Thanks for the input everyone. I’m going to go with solve ME. According to Charity Navigator, three employees of the OMF (CEO, CFO, CDO) earn a decent amount over 200’000$ (US) per year which feels slightly excessive especially when taking donations from people in precarious situations...

It’s surprising culturally how uncommon it is to participate in clinical research. Blood donation is something we’ve cemented as a way to give back and help, but participation in clinical tests really doesn’t have the same cultural standing.

No Abstract Provided My phone isn’t letting me copy exerpts from pdf. But the reason I’m sharing this is it’s a rather interesting peak into how pwME might be treated in China (it seems a diagnosis of “somatic depression” is likely). LINK (PDF)

(Just to be clear I’m not sharing this because I think cold water immersion helps ME, it probably leads to PEM, but because the impacts of exertion and stressors on the immune system is very interesting and might gives clues towards PEM mechanisms)

Abstract: This study aimed to identify signalling and metabolic pathways significantly impacted by alterations in cytokine and metabolic levels in response to acute cold exposure (CWI) following rest and exercise. In line with some previous studies, acute exposure to cold and exercise...

Abstract: The hemostatic system prevents and stops bleeding, maintaining circulatory integrity after injury. It directly interacts with the complement system, which is key to innate immunity. In coronavirus disease 2019 (COVID-19), dysregulation of the hemostatic and complement systems has been...

I almost feel we need to distinguish between two bits of PEM. PESE which is the worsening or triggering of symptoms, I wouldn’t be surprised if this also happens in various other diseases. PEBD? (post exertional baseline deterioration)? which is that “crash” where you have limited capacity do...

Coq10 gives me absolutely nothing. I cannot tell at all a difference between taking it and not. And my blood tests show very low levels.

This seems to be a pretty good argument in Solve ME’s favour

I think it was some stem-cell thing, the therapy being basically to stick the cells from your right arm into your left arm, which is an alt med treatment kind of thing that says it will cure 100 things but has RCTs showing it works for none. I’m possibly imaginging or misremembering this...

Simmaron does look quite interesting. I somehow had mixed them and polybio up in my head.

Incase anyone stumbles upon this in 2024 or later, the ME Association has had significant controversies recently and I wouldn’t recommend donating at this time. See thread

See Also: Which ME/CFS charity would you donate to right now for biomedical research? And: What are the best UK charities for ME? Following my receipt of a 50 USD charity gift card in a giveaway which only works with US Charities, I am left wondering what charity to spend it on. In the list of...

Fascinating. Note that the doses used commonly for apiprazole (5-30mg) and therefore likely what this study is referring to are quite different than the dose some ME patients report improvement from which is more like 0.1mg-4mg.

Abstract: Hepatic encephalopathy, defined as neuropsychiatric dysfunction secondary to liver disease, is a frequent decompensating event in cirrhosis. Its clinical impact is highlighted by a notable increase in patient mortality rates and a concomitant reduction in overall quality of life...

Yes. Ever been to a doctor and they can’t figure out what’s wrong with you, two things will be said. 1) Make sure to eat properly and exercise and reduce stress 2) Are you often anxious/stressed/depressed?

Abstract: COVID-19, a highly infectious disease, caused a worldwide pandemic in early 2020. According to the World Health Organization (WHO), COVID-19 has resulted in approximately 774 million cases and around 7 million deaths. The effects of COVID-19 are well known; however, there is a lack of...

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I sincerely hope you’re wrong. But a part of me knows you’re right.