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  1. Jonathan Edwards

    What is the Functional / Organic Distinction Actually Doing in Psychiatry and Neurology? (Preprint, 2020) Bell, Greco et al

    This is pure plagiarism. I am sure it was in a Monty Python sketch in 1977 with John Cleese as Monica Streeb-Grebeling.
  2. Jonathan Edwards

    The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread

    I agree, deeply disappointing. By all means listen to what Dr B has to say but one could have hoped for a more enlightening comment.
  3. Jonathan Edwards

    UK Times:'What if the thing that’s making you physically ill is your mind?', Feb 2020, Rumbelow [includes ME]

    I had a peep. It is too dreadful to even register for this month's free peepie. I was quite interested by Thought for Today today on BBC Radio 4 Today. A regular lady priest was agonising over the issue of whistleblowers in the context of the Chinese doctor who reported the coronavirus and got...
  4. Jonathan Edwards

    UK Times:'What if the thing that’s making you physically ill is your mind?', Feb 2020, Rumbelow [includes ME]

    I am tempted to make a Wonko-style nonsensical observation here - but only to provide a sort of 'Amen chorus' to an eternal truth. I have visions of dung beetles pushing balls of pseudoscientific dung up a sand dune to feed their larvae dressed in blue cardigans and other assorted 'chattering...
  5. Jonathan Edwards

    Prevalence of functional somatic syndromes and bodily distress syndrome in the Danish population: the DanFunD study, 2019, Petersen et al

    Which makes me wonder why as a rheumatologist seeing hundreds of new patients a year for thirty years I can recall seeing no more than a dozen people who I now realise had ME/CFS. Maybe ME/CFS is not referred specifically to rheumatologists but at least I should have seen more people with CFS...
  6. Jonathan Edwards

    Coronavirus - worldwide spread and control

    Most micro-organisms do not survive more than a few minutes at 80 Celsius (176F). As I understand it viruses of this sort tend not to like being completely dried out and away from host environment for very long anyway. 100 Celsius kills almost anything (212F) except strange spore forming...
  7. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    I don't really understand your scepticism @large donner. This is a virus that produces pneumonia bad enough to require hospital care in maybe one person in seven affected. It may kill as many as one in fifty and maybe more because the death figures ahave to be compared with the diagnosis figures...
  8. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    Worth reading the Kekule blog mentioned by Leila. Mortality from regular flu seems to be about 0.1%. For the new coronavirus the figure looks to be about 2% but if this is underestimated because of lag in diagnosis to death it might be above 10%. Strangely the MRC have put out an estimate of 18%...
  9. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    That blog looks like an excellent and unbiased assessment. The only thing I would quibble with is the idea that wearing a mask might raise ungrounded fears. I see a much bigger problem with people forgetting to be careful. Thus, yesterday evening I arrived at Heathrow and had to queue for nearly...
  10. Jonathan Edwards

    Coronavirus: Advice from ME organisations

    But Charles goes on to point out that things are getting more serious quite quickly. As I see it if everyone thinks that the risk is nearly zero then the virus is pretty well guaranteed to spread unnecessarily. I would personally advise everyone to take the risk seriously. I was amused to see...
  11. Jonathan Edwards

    BMJ Opinion: Peter Brindley and Matt Morgan: It’s time to be super heroes for scientific truth

    I am tempted to rephrase the old (unjustified as it was ) adage: Those who can understand science, do science. Those who can't become professors of the public understanding of science.
  12. Jonathan Edwards

    IgG stimulated β2 adrenergic receptor activation is attenuated in patients with ME/CFS, 2020, Hartwig et al

    I have not looked in detail but it seem as if they previously found a (very slight) increase in antibody levels to receptors in ME/CFS patients but now they find that these antibodies do nothing to the receptors, whereas ordinary people's antibodies do do something. That seems pretty confusing.
  13. Jonathan Edwards

    Potential benefits of a ketogenic diet to improve response and recovery from physical exertion in ME/CFS, 2020, Cossington et al

    If I remember correctly glycolysis means the oxygen-independent (anaerobic) breakdown of sugars to pyruvate. So it is not actually the 'burning' of sugar of aerobic respiration. I am not sure I can comment more usefully on the lactate results. Snow Leopard tends to be good on this.
  14. Jonathan Edwards

    POTS - definition, diagnosis and symptoms

    Three points that we have discussed before may be worth mentioning. Firstly, although I do not have the sources I am sure that in looking at this I found that it is recognised that some normal people show >30 bpm increase on standing and that this is not in itself diagnostic of 'POTS'...
  15. Jonathan Edwards

    'Recovery' statistics

    If someone has said 'for most people complete recovery is unusual' then it would be good to improve the English usage. Recovery is not usual or unusual for a person - it is unusual with a population.
  16. Jonathan Edwards

    Treating medically unexplained symptoms via improving access to psychological therapy (IAPT): major limitations identified, 2020, Geraghty and Scott

    Well, they will find a report, as part of the documentation of the next ME NICE guidelines, from this expert witness making it absolutely clear that the weight of evidence for CBT and GET is that they do not work. I won't mind having to justify that in a court of law under cross examination. I...
  17. Jonathan Edwards

    New MEA Guide: ME/CFS The Ten Key Aspects of Management | 05 February 2020

    I agree that a GP is likely to be better than a psychotherapist, but only to the extent that rather than 'managing ME/CFS' they may be honest enough to realise they have no clue what to do. I cannot see the basis for saying that people should be managed by GPs. They should be managed by...
  18. Jonathan Edwards

    New MEA Guide: ME/CFS The Ten Key Aspects of Management | 05 February 2020

    I am not sure I would say that. I think if I was someone who had recently developed ME/CFS I would find it confusing. The first section seems to blur two quite different points that ought to be separate. One is that it is important to have a clear idea what is likely to be wrong (making a...
  19. Jonathan Edwards

    Trial By Error: CBT and Irritable Bowel Syndrome

    I suppose you might want to deliver CBT at a bit of a distance if there is bowel trouble about. Maybe that's why they have invented this. The Monty Python script writers would have died for this stuff.
  20. Jonathan Edwards

    Trial By Error: CBT and Irritable Bowel Syndrome

    Windgassen seems an unfortunate name for anyone who wants to be taken seriously. Especially if they are in the business of bowel trouble. And they specialise in hot air.
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