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Good news if they have in fact found a pair of antibodies that work broadly (because we're running out due to viral evolution), but the availability of antibody treatment is in no way a substitute for vaccination.

I think it's basically that we have a reasonable hope that a mucosal vaccine might be better (based on animal studies), but we don't know for sure. Right now, the main factor driving transmission is evolution of the virus and it isn't clear to me how that might play out differently for a mucosal...

Definitely. It's based on whole grains, legumes, nuts, fruit and veg.

ONS says that they collected about 40% of the responses to this latest survey online (and a few by phone) and people were 30% more likely to report Long Covid online or by phone compared to in a in person interview, which is what they used before. So basically the increase in LC between the...

Right now, the most likely candidate for the next variant wave in the fall is BA.2.75, which is already growing quickly in India, Nepal and Australia. BA.2.75 is of course a descendent of BA.2, not BA.4/5, so it's not clear that a BA.4/5 vaccine would be any better than a BA.1 vaccine. In fact...

Many people get a flu vaccine every year (which is updated to 3 or 4 of the latest variants, similar to how the fall mRNA boosters will be updated to the latest variant, though they will also contain some of the original strain spike mRNA too). Flu vaccine is of course associated with lower risk...

Nath's hypothesis for what causes Long Covid is at 40:27 in the video, if you don't want to watch the whole thing. I believe this is neurological Long Covid specifically, but Nath includes exercise intolerance and fatigue in this. Very little detail, seems to be basically leakage into the brain...

Brain fog seems to be having a media moment in the last week or two. It doesn't seem helpful to me to separate out the individual symptom of brain fog from the many others that usually accompany it (as in ME). I have doubts that neurological injury is a significant driver of LC brain fog rather...

Interesting that this is from Bristol-Myers Squibb (the drug company). Patients self-identified as having CFS, though almost all said it was diagnosed by a doctor. Good to see about half of them were house- or bed-bound Viral testing was PCR of blood samples. 7 CFS with HHV6 out of 166, 1...

Abstract Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating condition that can lead to severe impairment of physical, psychological, cognitive, social, and occupational functions. The cause of ME/CFS remains incompletely understood. There is no clinical...

Yes, I think they have done some shifting in order to arrive at the conclusions they want to arrive at here. The corresponding author's tweets here make it clear that they're trying to play a gotcha game by conflating any kind of symptom at 6 months that affects the person in any way with Long...

Abstract In a national cohort of 12,788 adolescents, those reporting parents experiencing ongoing problems from COVID-19 had 1.79-fold (95%CI: 1.58-2.02) higher odds of experiencing LONG COVID 6 months after a SARS-CoV-2 PCR-test than those reporting parents without ongoing symptoms...

It's a single author paper in a junk journal from someone who concludes with a pitch for "TransdermOil TM". He seems to have written similar papers about B12 and autism, sleep disorders in children and depression. It has a bunch of comparisons between patients and controls with no p-values, 316...

This looks like complete garbage from someone who is trying to sell B12 oil.

There does seem to be a fair amount of evidence for this from the ONS data and other studies. The risk reduction due to vaccination is probably more significant, but it does seem that Omicron is less likely to lead to Long Covid. ONS found a roughly 50% reduction for double vaccinated people...

Interesting. Very different for me. It was always sustained intensity, usually an hour or more. I never had any trouble with lifting all kinds of heavy things, straining or anything like that. I would agree that working with my hands above my head was worse though, but only for sustained...

Relative hypercoagulopathy of the SARS-CoV-2 Beta and Delta variants when compared to the less severe Omicron variants is related to TEG parameters, the extent of fibrin amyloid microclots, and the severity of clinical illness. Abstract: Earlier variants of SARS-CoV-2 have been associated with...

I think you could probably, with some effort, round up enough people who were diagnosed in the past with 50% reduction in activity levels, but who have currently recovered to near normal levels of activity but still experience PEM. I'd definitely agree that it would be near impossible to...

These are probably pretty reasonable parameters for including people in studies and such, but my own experience runs somewhat counter to this. I think whatever ME is, it can be much milder than we generally think. In between a fairly significant episode as a teenager and my current sorry state...

There's actually a fair bit of research on this subject for flu, but the results vary. In NZ, they say 80% are asymptomatic based on random population level-sampling, but other studies have found lower numbers. What's interesting with Covid is that the number of asymptomatic infections...